Coronavirus News and Research

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Reduced expression of interleukin 8 and interferon-gamma cytokines identified in long COVID

In a new study, researchers compared serum cytokine expression among healthy individuals and those with PASC [post-acute sequelae of coronavirus disease 2019 (COVID-19)].

10 Oct 2022

Effect of COVID-19 mRNA vaccination on COVID-19 severity during Omicron BA.4 and BA.5 predominance periods

In a new study, researchers estimated the association of first-generation messenger ribonucleic acid (mRNA) vaccines (BNT162b2, mRNA-1273) with coronavirus disease 2019 (COVID-19)-related medical encounters.

10 Oct 2022

Silver nanoparticle and polyurethane composite provides potential coating options to limit fomite transmission of SARS-CoV-2

In a new study, researchers synthesized and evaluated a silver and polyurethane nanocomposite surface coating material that exhibits antiviral activity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

7 Oct 2022

Histone mimicry by SARS-CoV-2 protein disrupts epigenetic regulation of host cells

Researchers demonstrated that the SARS-CoV-2 protein functions as a histone mimic to disrupt the epigenetic regulation of host cells.

7 Oct 2022

Study evaluates efficacy of a candidate SARS-CoV-2 subunit vaccine to protect endangered black-footed-ferrets

In a new study, researchers assessed the safety, efficacy, and immunogenicity of a candidate SARS-CoV-2 subunit vaccine in black-footed ferrets (BFF), and investigated the susceptibility of these endangered North American mammals to the virus.

7 Oct 2022

The effect of ORF3c, a SARS-CoV-2 accessory protein, on cellular innate immune responses, autophagy, and lung cell mitochondrial metabolism

Researchers explored the role of the ORF3c, a SARS-CoV-2 accessory protein not so extensively studied as yet.

7 Oct 2022

Neonatal mice-based model established that allows for the transmission of clinical SARS-CoV-2 isolates

Researchers established a neonatal mice model that enabled SARS-CoV-2 transmission.

7 Oct 2022

The magnitude and duration of the protective effect of prior infection and hybrid immunity against Omicron infection and severe disease

Researchers reviewed the duration and magnitude of the protective effect of previous SARS-CoV-2 infections and hybrid immunity against SARS-CoV-2 Omicron variant of concern infections and COVID-19 severity.

7 Oct 2022

Study using human and animal-derived cell lines suggests human origin of SARS-CoV-2 Omicron variant

Researchers examined the replicative capacity of seven SARS-CoV-2 isolates in 17 cell lines to understand their phenotypic variations and host range.

7 Oct 2022

COVID‐19 pathology across different tissues

Researchers investigated COVID-19 pathophysiology in multiple tissues, including the lungs, kidneys, heart, and brain, for a deeper understanding of its acute and long‐term symptoms.

7 Oct 2022

Exploring the biomarker profiles in severe COVID-19

In new research, researchers estimated the D-dimer levels and characterized lymphocyte subsets and cytokine profiles in severe coronavirus disease 2019 (COVID-19) patients.

7 Oct 2022

Vaccine-induced neutralizing and non-neutralizing antibody activity against SARS-CoV-2

A new study demonstrated that vaccine-induced antibody functions against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) diminish with age.

7 Oct 2022

Acute kidney injury in hospitalized COVID-19 patients

In a new study, researchers examined the phenotypes of acute kidney injury (AKI) in hospitalized coronavirus disease 2019 (COVID-19) patients.

7 Oct 2022

Study suggests an immunological benefit of combining previous natural infection with vaccination against COVID-19 using a combination of different vaccine platforms

Researchers explored SARS-CoV-2-targeted immune responses among COVAC1 participants who received a novel saRNA vaccine followed by the mRNA BNT162b2 vaccine BNT162b2 vaccine, with or without prior COVID-19 history.

7 Oct 2022

Successful rollout of vaccine has led to dramatic reduction in long COVID clinic referrals

Referrals to Cambridge's long COVID clinic fell dramatically in the period August 2021 to June 2022, which researchers say is likely due to the successful rollout of the vaccine.

7 Oct 2022

MSU researchers use big data and AI to identify existing drugs to fight new COVID-19 variants

MSU researchers are using big data and AI to identify current drugs that could be applied to treat new COVID-19 variants.

6 Oct 2022

Scientists investigate the antibody titers post-mRNA COVID-19 booster vaccine in the elderly

The coronavirus 2019 disease (COVID-19) pandemic has affected millions worldwide and claimed multiple lives.

6 Oct 2022

Clinical trials of novel COVID-19 vaccine developed in Brazil to begin soon

Testing on humans of a novel COVID-19 vaccine developed in Brazil will begin this year. It performed well in animal trials, as reported in an article published in August in Nature Communications.

6 Oct 2022

KHN’s ‘What the Health?’: Looking ahead to the lame-duck session

When the lame-duck Congress returns to Washington after Election Day, it will face a long list of health items needing attention before the end of the year, including setting overall spending for health programs and averting a series of Medicare payment cuts to health care providers.

6 Oct 2022

The present and future role of nurses in the new digital health era

Researchers reviewed nursing practices and additional skills required to be mastered by nurses in the digital health revolution, with the use of digital technologies exponentially increasing during the COVID-19 pandemic.

6 Oct 2022

Coronavirus News and Research

Reduced expression of interleukin 8 and interferon-gamma cytokines identified in long COVID

Effect of COVID-19 mRNA vaccination on COVID-19 severity during Omicron BA.4 and BA.5 predominance periods

Silver nanoparticle and polyurethane composite provides potential coating options to limit fomite transmission of SARS-CoV-2

Histone mimicry by SARS-CoV-2 protein disrupts epigenetic regulation of host cells

Study evaluates efficacy of a candidate SARS-CoV-2 subunit vaccine to protect endangered black-footed-ferrets

The effect of ORF3c, a SARS-CoV-2 accessory protein, on cellular innate immune responses, autophagy, and lung cell mitochondrial metabolism

Neonatal mice-based model established that allows for the transmission of clinical SARS-CoV-2 isolates

The magnitude and duration of the protective effect of prior infection and hybrid immunity against Omicron infection and severe disease

Study using human and animal-derived cell lines suggests human origin of SARS-CoV-2 Omicron variant

COVID‐19 pathology across different tissues

Exploring the biomarker profiles in severe COVID-19

Vaccine-induced neutralizing and non-neutralizing antibody activity against SARS-CoV-2

Acute kidney injury in hospitalized COVID-19 patients

Study suggests an immunological benefit of combining previous natural infection with vaccination against COVID-19 using a combination of different vaccine platforms

Successful rollout of vaccine has led to dramatic reduction in long COVID clinic referrals

MSU researchers use big data and AI to identify existing drugs to fight new COVID-19 variants

Scientists investigate the antibody titers post-mRNA COVID-19 booster vaccine in the elderly

Clinical trials of novel COVID-19 vaccine developed in Brazil to begin soon

KHN’s ‘What the Health?’: Looking ahead to the lame-duck session

The present and future role of nurses in the new digital health era

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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