Corticosteroid News and Research

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Corticosteroids are any steroid hormones made in the adrenal cortex (the outer part of the adrenal gland). They are also made in the laboratory. Corticosteroids have many different effects in the body, and are used to treat many different conditions. They may be used as hormone replacement, to suppress the immune system, and to treat some side effects of cancer and its treatment. Corticosteroids are also used to treat certain lymphomas and lymphoid leukemias.

Nonsurgical treatment options effective for sufferers of chronic rhinosinusitis

For sufferers of chronic rhinosinusitis, surgery is often the only treatment option due to the severity of their condition.

15 Oct 2019

Tips to manage symptoms and flare-ups in children with eczema

Atopic dermatitis (also known as eczema) is a common skin condition in babies. It affects up to 25% of children, and an estimated 60% of people with eczema develop it during their first year of life.

10 Oct 2019

Triple-drug combo inhaler for asthmatics with poor symptom control

New research shows that asthmatics who have poor symptom control could be benefited by using a three-drug combination inhaler. The standard treatment for these patients is a two-drug combination of an inhaled corticosteroid (ICS) and a long acting beta 2 agonist (LABA). The third ingredient added to the mix is a long acting muscarinic antagonist, add the researchers. This combination successfully improved lung function and reduced exacerbations of asthma wrote the researchers.

1 Oct 2019

New clinical practice guideline published for adults with community acquired pneumonia

The American Thoracic Society and the Infectious Diseases Society of America have published an official clinical guideline on the diagnosis and treatment of adults with community acquired pneumonia (CAP) in the ATS's Oct. 1 American Journal of Respiratory and Critical Care Medicine.

1 Oct 2019

Study assesses treatment options in African Americans with poorly controlled asthma

A new study of African Americans with poorly controlled asthma, found differences in patients' responses to commonly used treatments. Contrary to what researchers had expected, almost half of young children in the study responded differently than older children and adults, and than white children in prior studies.

1 Oct 2019

Clinical trial to evaluate efficacy and safety of new treatment for giant cell arteritis

An international, multicenter phase II clinical trial is evaluating the efficacy and safety of mavrilimumab co-administered with a 26-week corticosteroid taper in patients with giant cell arteritis.

26 Sep 2019

Two uveitis drugs perform similarly in a head-to-head clinical trial

Methotrexate and the more expensive mycophenolate mofetil performed similarly in a head-to-head clinical trial that compared the two drugs for treating noninfectious uveitis, an eye disease that accounts for up to 15% of blindness in the U. S.

11 Sep 2019

Wild birds help shed light on stress resilience in humans

Stress is a common everyday experience, particularly in the world today. A new study might open the doors for the prevention and treatment of stress disorders, thanks to wild songbirds.

21 Jul 2019

$FDA grants accelerated approval to new treatment for refractory multiple myeloma$

FDA grants accelerated approval to new treatment for refractory multiple myeloma

Today, the U.S. Food and Drug Administration granted accelerated approval to Xpovio (selinexor) tablets in combination with the corticosteroid dexamethasone for the treatment of adult patients with relapsed refractory multiple myeloma who have received at least four prior therapies and whose disease is resistant to several other forms of treatment, including at least two proteasome inhibitors, at least two immunomodulatory agents, and an anti-CD38 monoclonal antibody.

3 Jul 2019

First treatment approved by FDA for chronic rhinosinusitis with nasal polyps

The U.S. Food and Drug Administration today approved Dupixent (dupilumab) to treat adults with nasal polyps (growths on the inner lining of the sinuses) accompanied by chronic rhinosinusitis (prolonged inflammation of the sinuses and nasal cavity).

26 Jun 2019

New intervention shows promise for relief of shoulder pain in wheelchair users with spinal cord injury

A New Jersey team of researchers has reported the successful, long-term relief of chronic refractory shoulder pain in a wheelchair user with spinal cord injury following a single injection of autologous, micro-fragmented adipose tissue into the affected shoulder joint.

12 Jun 2019

New immunosuppressive regimens may improve outcomes for kidney transplant patients

Preliminary results from a $5.2 million clinical trial led by University of Cincinnati researchers show that the immunosuppressive drug belatacept can help safely and effectively treat kidney transplant patients without the negative long-term side effects of traditional immunosuppressive regimens, the study's leaders announced this week.

6 Jun 2019

Dyson-Hudson receives grant to study effectiveness of new treatment for shoulder pain

Trevor Dyson-Hudson, MD, director of the Center for Spinal Cord Injury Research at Kessler Foundation, was awarded a $549,000 grant by the New Jersey Commission on Spinal Cord Research.

31 May 2019

Innovative treatment improves vision of a patient suffering from melanoma-associated retinopathy

Innovative treatment has improved the vision of a patient suffering from a rare cancer-related syndrome affecting the eye, new research in the journal JAMA Ophthalmol reports.

30 Apr 2019

Sweden shows greatest improvement in saving extremely preterm babies

The survival rate among extremely preterm babies has greatly improved in Sweden, a country that offers top-class neonatal care, a study led from Karolinska Institutet published in the esteemed journal JAMA reports.

27 Mar 2019

Drug that prevents respiratory ailments in preemies reduces healthcare costs

A new study from researchers at Columbia University Vagelos College of Physicians and Surgeons shows that a drug given to some pregnant women to prevent severe respiratory ailments in preterm newborns reduces healthcare costs.

14 Mar 2019

Exposure to antenatal corticosteroid therapy associated with reduced fetal growth

Infants exposed to antenatal corticosteroid therapy to accelerate lung maturation have a clinically significant reduction in birth size, according to a new of study of 278,508 births published this week in PLOS Medicine by Alina Rodriguez of the University of Lincoln and Imperial College London, UK, and colleagues.

28 Feb 2019

Preterm babies whose mother's received steroid treatment have lower birth weight

Steroid injections given to mothers at risk of giving birth prematurely are linked to babies being born with lower body weights.

26 Feb 2019

Machine learning technique helps predict which asthma patients respond to corticosteroid therapy

Physicians will be able to predict which of their patients with severe asthma are likely to benefit from treatment with systemic corticosteroids -- and which might only suffer their side effects -- with help from a dozen clinical variables researchers have identified using machine learning techniques.

20 Feb 2019

Fish oil does not appear to provide therapeutic benefits for obese teens with uncontrolled asthma

Fish oil does not appear to improve asthma control in adolescents and young adults with uncontrolled asthma who are overweight or obese, according to new research published online in the Annals of the American Thoracic Society.

25 Jan 2019

Corticosteroid News and Research

Nonsurgical treatment options effective for sufferers of chronic rhinosinusitis

Tips to manage symptoms and flare-ups in children with eczema

Triple-drug combo inhaler for asthmatics with poor symptom control

New clinical practice guideline published for adults with community acquired pneumonia

Study assesses treatment options in African Americans with poorly controlled asthma

Clinical trial to evaluate efficacy and safety of new treatment for giant cell arteritis

Two uveitis drugs perform similarly in a head-to-head clinical trial

Wild birds help shed light on stress resilience in humans

FDA grants accelerated approval to new treatment for refractory multiple myeloma

First treatment approved by FDA for chronic rhinosinusitis with nasal polyps

New intervention shows promise for relief of shoulder pain in wheelchair users with spinal cord injury

New immunosuppressive regimens may improve outcomes for kidney transplant patients

Dyson-Hudson receives grant to study effectiveness of new treatment for shoulder pain

Innovative treatment improves vision of a patient suffering from melanoma-associated retinopathy

Sweden shows greatest improvement in saving extremely preterm babies

Drug that prevents respiratory ailments in preemies reduces healthcare costs

Exposure to antenatal corticosteroid therapy associated with reduced fetal growth

Preterm babies whose mother's received steroid treatment have lower birth weight

Machine learning technique helps predict which asthma patients respond to corticosteroid therapy

Fish oil does not appear to provide therapeutic benefits for obese teens with uncontrolled asthma

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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