Corticosteroid News and Research

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Corticosteroids are any steroid hormones made in the adrenal cortex (the outer part of the adrenal gland). They are also made in the laboratory. Corticosteroids have many different effects in the body, and are used to treat many different conditions. They may be used as hormone replacement, to suppress the immune system, and to treat some side effects of cancer and its treatment. Corticosteroids are also used to treat certain lymphomas and lymphoid leukemias.

Advair reduces asthma-related hospitalization and emergency department visits

Advair Diskus (fluticasone propionate and salmeterol inhalation powder) was associated with fewer asthma-related hospitalizations and emergency department (ED) visits in pediatric patients when compared to the use of inhaled corticosteroids (ICS) alone, and use of Advair by pediatric and adult patients through the summer was associated with fewer hospitalizations and ED visits in the fall.

17 Mar 2008

Total ankle replacement gaining foothold in upstate New York

A procedure aimed at not only relieving pain from arthritic ankles, but providing new-found mobility for patients, is gaining a foothold in upstate New York.

13 Mar 2008

Low dose inhaled corticosteroids improve lung function in mild asthma patients

A study by the Woolcock Institute of Medical Research in Sydney is the first to demonstrate that in patients with very mild or well-controlled asthma, regular treatment with low dose ICS leads to significantly better day-to-day lung function.

11 Mar 2008

Nasal polyps from analgesics

If a patient develops respiratory problems after taking analgesics, this indicates that the active substances are poorly tolerated.

11 Mar 2008

Quality of care for inflammatory bowel disease patients can be improved

Inflammatory bowel disease (IBD) is a chronic recurrent gastrointestinal disease.

26 Feb 2008

$1-year results of bronchial thermoplasty in refractory asthma$

1-year results of bronchial thermoplasty in refractory asthma

Asthmatx, Inc. has announced the publication of data from the Research in Severe Asthma (RISA) Trial of bronchial thermoplasty in the American Journal of Respiratory and Critical Care Medicine (AJRCCM, 2007; 176:1185-1191).

12 Feb 2008

Baxter's multiple-dose vial Heparin linked to severe allergic reactions

The U.S. Food and Drug Administration announced today that Baxter Healthcare Corporation has temporarily stopped manufacturing multiple-dose vials of the injectable blood-thinning drug heparin due to reports of serious allergic reactions and hypotension (low blood pressure) in patients who receive high "bolus" doses of the drug.

11 Feb 2008

Allergic-like reactions occur in premedicated patients

Allergic-like reactions can occur in patients (both children and adults) when given gadolinium containing contrast agents, even if they have been pre-medicated with corticosteroids and antihistamines, according to a recent study conducted by researchers at the University of Michigan Health Systems in Ann Arbor.

11 Feb 2008

New discoveries on what does and doesn't affect immune system

Scientists know that a number of factors can affect the body's immune system: poor diet, certain steroids, chronic stress. Now researchers at Michigan State University have discovered that an appetite-controlling hormone also affects the immune system, while natural versions of certain steroids do not.

4 Feb 2008

FDA approves only once-daily inhaled corticosteroid for children

Schering-Plough Corporation has announced that the U.S. Food and Drug Administration (FDA) has approved ASMANEX TWISTHALER 110 mcg (mometasone furoate inhalation powder) for the maintenance treatment of asthma as a preventive therapy in patients 4 to 11 years of age.

4 Feb 2008

Severe asthma may be a different form of the disease

A multi-center research project to investigate severe asthma has found a key physiological difference between severe and non-severe forms of the disease, a finding that could help explain why those with severe asthma do not respond well to treatment.

31 Jan 2008

New therapy reduces mortality in patients with severe COPD

Patients with severe COPD may benefit more from therapy that combines salmeterol and fluticasone [SFC] than treatment with tiotropium, according to results from a long-term, multi-center study, "Investigating New Standards for Prophylaxis in Reducing Exacerbations" (INSPIRE) that directly compared the two therapies.

2 Jan 2008

Big toe injuries

With the Fall sports season winding down and the indoor sport season now underway, the importance of understanding and preventing foot injuries is top of mind for thousands of athletes around the country.

28 Dec 2007

Pain treatment in the field: Good for soldiers' comfort and better for rebuilding troop strength

Noncombat-related acute and recurrent chronic pain are the leading causes of soldier attrition in modern war, with the return-to-duty rate as low as 2 percent when these soldiers are treated outside the theaters of operation.

18 Dec 2007

Combining medications often best strategy to battle rheumatoid arthritis

For patients with rheumatoid arthritis, combining one well-known, lower cost synthetic drug with one of six biologic medications often works best to reduce joint swelling or tenderness, according to a new report funded by the Agency for Healthcare Research and Quality, part of the U.S. Department of Health and Human Services.

18 Dec 2007

Commonly available antibiotic targets difficult asthma

Hunter researchers have shown that a commonly available antibiotic can improve the quality of life of patients with difficult asthma, and may also generate significant health care savings.

18 Dec 2007

$Factors identified to predict hip fracture in postmenopausal women$

Factors identified to predict hip fracture in postmenopausal women

A clinical model that includes 11 factors has been developed to help predict the 5-year risk of hip fracture in postmenopausal women, according to a study in the November 28 issue of JAMA.

27 Nov 2007

$Model provides risk factors for hip fractures in older women$

Model provides risk factors for hip fractures in older women

Experts say there are around 329,000 hip fractures in postmenopausal women in the United States each year and up to 24% of hip fracture patients over 50 die within one year of the injury because of complications related to the injury itself or the extended recovery period.

27 Nov 2007

X-stop procedure helps relieve pain as a result of spinal stenosis

A new minimally invasive procedure is hitting its mark with certain types of low back and leg pain sufferers, significantly reducing their pain and disability.

20 Nov 2007

Combining medications often best strategy to battle rheumatoid arthritis

For patients with rheumatoid arthritis, combining one well-known, lower-cost synthetic drug with one of six biologic medications often works best to reduce joint swelling or tenderness, according to a new report by researchers at the RTI International-University of North Carolina at Chapel Hill Evidence-based Practice Center, which is sponsored by the Agency for Healthcare Research and Quality.

19 Nov 2007