Cortisol is a hormone made by the adrenal cortex (the outer layer of the adrenal gland). It helps the body use glucose (a sugar), protein, and fats. Cortisol made in the laboratory is called hydrocortisone. It is used to treat many conditions, including inflammation, allergies, and some cancers. Cortisol is a type of glucocorticoid hormone.
Today, The Endocrine Society released a new clinical practice guideline on the diagnosis and treatment of congenital adrenal hyperplasia (CAH). The guideline features a series of evidence-based clinical recommendations developed by an expert task force.
Researchers at The University of Western Ontario have provided the first direct evidence using a biological marker, to show chronic stress plays an important role in heart attacks.
If your body releases cortisol with fixed regularity then you can cope with stress better, says NWO-funded researcher Angela Sarabdjitsingh. She investigated the rhythm of corticosterone production in rats. This rat hormone is comparable to the human stress hormone cortisol. Rats deal considerably less well with stress if the pattern of corticosterone release changes. An irregular release pattern is a characteristic of chronic stress and stress-related diseases. It might therefore be possible to treat these by restoring the rhythm.
All humans are synchronised to the rhythmic light-dark changes that occur on a daily basis. Rhythms in physiological and biochemical processes and behavioural patterns persist in the absence of all external 24-hour signals from the physical environment, with a period that is close to 24 hours
Being married has often been associated with improving people's health, but a new study suggests that having that long-term bond also alters hormones in a way that reduces stress.
People suffering from diabetes-related foot ulcers show different rates of healing according to the way they cope and their psychological state of mind, according to new research by a health psychologist at The University of Nottingham.
A remote Canadian island is being used to simulate isolated space flight conditions for a NASA-funded medical research study that could produce important information to assist astronauts in potential long duration flights to Mars or an asteroid.
MDMA (-3,4-methylenedioxymethamphetamine, also known as Ecstasy), may one day offer hope for individuals with posttraumatic stress disorder (PTSD), even people for whom other treatments have failed. Clinical trial results out today in the Journal of Psychopharmacology, published by SAGE, suggests that MDMA can be administered to subjects with PTSD without evidence of harm and could offer sufferers a vital window with reduced fear responses where psychotherapy can take effect.
Rebuilding schools after Hurricane Katrina and providing supportive environments and relationships have helped many children reduce their levels of overall trauma from the hurricane that devastated the Gulf Coast in August 2005, according to a new study. A second study found that girls had distinct stress reactions from boys in the aftermath of the storm.
Now, in the first such study in living humans, researchers at UCLA suggest a cause, and it's not psychological, but physical: atrophy of a specific region of the hippocampus, a critical part of the brain involved in mood and memory, among other functions.
Marianne Kraugerud's doctoral research has led to the discovery that individual variants of the environmental pollutants PCB and PFC can affect several of the body's hormone systems in a more complex way than previously supposed. Humans and animals are constantly exposed to these toxins through the food they eat and the air they breathe. Kraugerud concludes that the impact of these pollutants should be taken into account when carrying out risk appraisals of PCB and PFC.
New research shows that a unique strain of laboratory mice characterized at Penn State University has behavioral, hormonal, and neurochemical characteristics that are similar to those of human patients with drug-resistant forms of depression.
Vitae Pharmaceuticals, Inc., an integrated discovery and development company, today announced that it has earned a $14 million clinical milestone payment from Boehringer Ingelheim, one of the world's 20 leading pharmaceutical companies. Vitae's 11beta-hydroxysteroid dehydrogenase (HSD)-1 is targeted for the treatment of diabetes and metabolic syndrome-related diseases in a strategic alliance with Boehringer Ingelheim. The payment recognizes Boehringer Ingelheim's recent advancement of a small molecule inhibitor of 11beta-HSD-1 into Phase I clinical trials.
For anyone who knows the racing, "misfiring" brain associated with today's multitasking lifestyles, finding a safe, effective remedy to achieve calm can be a challenge. Women-run Rainbow Light® Nutritional Systems, a leader in natural nutrition for nearly 30 years, has developed a breakthrough remedy to calm the "busy brain" that can impair mental clarity and cause restless sleep.
Linagliptin phase III data were presented for the first time this week at the 70th Scientific Sessions of the American Diabetes Association (ADA), showing that this investigational compound, a dipeptidyl peptidase (DPP)-4 inhibitor, achieved significant, sustained and clinically meaningful reductions in blood glucose as measured by haemoglobin A1c (HbA1c), fasting plasma glucose (FPG), and postprandial glucose (PPG) concentrations.(1-6) Linagliptin is being investigated by Boehringer Ingelheim as a once-daily oral treatment in type 2 diabetes.
Data from four pivotal Phase III clinical trials demonstrate that linagliptin achieved statistically significant and sustained reductions in blood sugar as measured by hemoglobin A1c, fasting plasma glucose and postprandial glucose. Boehringer Ingelheim Pharmaceuticals, Inc. is investigating the dipeptidyl peptidase 4 inhibitor as an oral once-daily tablet, as monotherapy and combination therapy, to treat type 2 diabetes.
Merck today announced that the U.S. Food and Drug Administration (FDA) has approved DULERA® (mometasone furoate and formoterol fumarate dihydrate) Inhalation Aerosol, a new fixed-dose combination asthma treatment for patients 12 years of age and older. DULERA is not indicated for the relief of acute bronchospasm. DULERA combines an inhaled corticosteroid (mometasone furoate) with a long-acting beta2-agonist (formoterol fumarate).
Treatments for mental illnesses are based on medicines and on therapies. Nevertheless it is not being done much to develop effective systems to prevent the appearance of such illnesses. In January starts the European initiative OPTIMI to contribute to the early detection of depression. The research group Labpsitec of the Department of Basic and Clinical Psychology and Psychobiology at the Universitat Jaume I of Castellón, takes part in the project with the design of evaluation strategies for people in situation of risk.
A new study at the University of Alabama at Birmingham confirms the relationship between depression and abdominal obesity, which has been linked to an increased risk for cancer and cardiovascular disease.
When we get angry, the heart rate, arterial tension and testosterone production increases, cortisol (the stress hormone) decreases, and the left hemisphere of the brain becomes more stimulated. This is indicated by a new investigation lead by scientists from the University of Valencia that analyses the changes in the brain's cardiovascular, hormonal and asymmetric activation response when we get angry.
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