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Scientists find that lipocalin 2 protein disables macrophages in bacterial pneumonia

Macrophages, also known as scavenger cells, play an important role in defending against bacteria and pathogens by activating inflammatory processes. In cases of lung inflammation (pneumonia) caused by pneumococcal bacteria, this important immune response function is hampered and blocked by the protein lipocalin 2.

22 Jul 2013

Scientists discover chain of molecular mechanisms set in motion by glucocorticoids

These scientists under the leadership of Martin Bilban from the Clinical Institute of Laboratory Medicine at the MedUni Vienna discovered a chain of molecular mechanisms, which is kick-started by the formation of glucocorticoids.

12 Jul 2013

Platelet-rich plasma holds great promise in treating knee OA

A study by researchers from Hospital for Special Surgery has shown that platelet-rich plasma (PRP) holds great promise for treating patients with knee osteoarthritis.

13 Feb 2013

Patients with COPD more likely to develop serious bacterial infections

It is well known that COPD patients run a higher risk of contracting respiratory infections. However, a new thesis from Lund University in Sweden shows that they are also at higher risk of other bacterial infections, such as tuberculosis (TB) and pneumococcal and staphylococcal infections that can cause serious illness.

16 Jan 2013

Spacemen upset sodium balance theories

Levels of salt in the body and sodium in the urine fluctuate over fixed cycles that are independent of salt intake, shows a space simulation study.

15 Jan 2013

Scientists invent scalable method to make polyhydroxylated steroids

Scientists at The Scripps Research Institute (TSRI) have achieved a feat in synthetic chemistry by inventing a scalable method to make complex natural compounds known as "polyhydroxylated steroids." These compounds, used in heart-failure medications and other drugs, have been notoriously problematic to synthesize in the laboratory.

4 Jan 2013

Widening treatment options for parotid duct stenoses

Parotidectomy should no longer be regarded as a routine treatment for parotid duct stenosis and should be indicated only in individual cases, report researchers.

16 Oct 2012

New method to precisely predict premature birth

Babies born early run a greater risk of serious complications. The researchers at the Sahlgrenska Academy, University of Gothenburg, Sweden, have now developed a method to predict if pregnant women with preterm contractions will give birth within seven days. The method offers new possibilities to delay delivery and prepare care for the premature baby.

17 Sep 2012

Optimi prototype effectively predicts people at risk of depression

The computing tool, developed by researchers at the Universitat Jaume I in Castellón, the Universitat Politècnica of València and the Universitat de València, along with professionals from the company everis, is able to predict if a person with a high-stress level is at risk of becoming depressed, based on the study of a series of physiological and psychological variables in which artificial intelligence techniques are used.

24 May 2012

Loyola’s hand surgeons see more patients with thumb arthritis

As baby boomers age, orthopedic surgeons are seeing more and more patients, especially women, who suffer from debilitating arthritis of the thumb.

4 Apr 2012

Specific precautions must be taken for individuals on longer-term oral glucocorticoid therapy

Millions of people around the world are prescribed glucocorticoids for a wide variety of inflammatory conditions, including, rheumatoid arthritis, asthma and inflammatory bowel diseases. Although they are effective and widely used, one of the potentially serious side effects of these medications is glucocorticoid-induced osteoporosis.

28 Mar 2012

African Americans more likely to develop keloid after head and neck surgery

African Americans are seven times more likely than Caucasians to develop an excessive growth of thick, irregularly shaped and raised scarring on their skin - known as a keloid - following head and neck surgery, according to a new study from Henry Ford Hospital in Detroit.

7 Mar 2012

Researchers discover HS1.2 enhancer as the cause of SLE

A "genetic accelerator" is responsible for the most severe cases of Lupus (systemic lupus erythemathosus), an autoimmune disease: the accelerator, called enhancer HS1.2, speeds up the activity of some critical genes of the immune system involved in the disease.

17 Jan 2012

New possibilities for effective treatment of psoriasis

Researchers at Link-ping University in Sweden are now launching a plan to effectively treat psoriasis.

11 Jan 2012

Indiscriminate expensive imaging has little clinical benefit in patients requiring epidural steroid injections

Johns Hopkins-led research suggests that routine MRI imaging does nothing to improve the treatment of patients who need injections of steroids into their spinal columns to relieve pain. Moreover, MRI plays only a small role in a doctor's decision to give these epidural steroid injections (ESIs), the most common procedure performed at pain clinics in the United States.

14 Dec 2011

N-acetylcysteine plus cortisone shows promise against acute alcoholic hepatitis

Acute alcoholic hepatitis is one of the most serious forms of alcoholic liver disease, affecting individuals with chronic excessive alcohol consumption, which generally equates to more than 50 grams of alcohol per day, over a period of more than three to six months. The disease is characterized by liver failure and acute jaundice (icterus), which may induce a coma through liver failure and an ensuing death rate of between 40-45% within the first six months.

11 Nov 2011

DuoCort Pharma granted marketing authorization for adrenal insufficiency drug, Plenadren in Europe

The Swedish specialty pharma company, DuoCort Pharma, announced today that the European Commission has granted a European Marketing Authorisation for Plenadren (hydrocortisone, modified release tablet), an orphan drug for treatment of adrenal insufficiency in adults, bringing these patients their first pharmaceutical innovation in over 50 years.

7 Nov 2011

Quick injection of cortisone can prevent PTSD

As soldiers return home from tours in Afghanistan and Iraq, America must cope with the toll that war takes on mental health. But the treatment of Post Traumatic Stress Disorder (PTSD) is becoming increasingly expensive, and promises to escalate as yet another generation of veterans tries to heal its psychological wounds.

4 Oct 2011

Tips to minimize risk of bug bites and related illnesses

While the image of a bug crawling on your arm or a creepy crawler snuggling up in your bed is enough to make you flinch, most bug bites are harmless and disappear on their own in a matter of days. Other insects, however, can spread disease and cause severe reactions that require medical attention.

4 Aug 2011

Study proves efficacy of cellulose powder, without any adverse effects, in treatment of hay fever for children

A cellulose powder has been used increasingly for many years against allergic rhinitis. Still, there has been a shortage of scientific evidence for its efficacy in seasonal allergic rhinitis (hay fever), particularly in children. Now, however, scientists from the Sahlgrenska Academy and the Department of Plant and Environmental Sciences at the University of Gothenburg have proven that the cellulose powder reduces symptoms of seasonal allergic rhinitis in children, without any adverse effects.

29 Jun 2011