CpG News and Research

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Facial recognition algorithms show genetic similarities in genetically unrelated look-alike humans

In a new study, researchers identified look-alike humans who were genetically unrelated using facial recognition (FR) algorithms for multi-omics studies.

25 Aug 2022

Assessing immunization capacity of vaccine platforms with DNA origami harboring SARS-CoV-2 receptor binding domain

Researchers demonstrated that vaccine frameworks containing deoxyribonucleic acid (DNA) origami possessing SARS-CoV-2 receptor-binding domain induce strong protective immunity.

8 Aug 2022

Charged nanoparticles combined with a vaccine effective in eliminating melanoma tumors in mice

Cancers in humans have all sorts of ways to survive and thrive: Cells and tumors alike engage in devious means to deflect, deceive, and evade detection by our bodies’ immune systems.

20 Jul 2022

COVID-19 vaccination with bacterial peptide conjugated to receptor-binding domain elicits potent immune response

In a new study, researchers assessed the efficiency of immunization with a bacterial peptide conjugated to the SARS-CoV-2 receptor-binding domain against SARS-CoV-2 infection.

6 Jul 2022

Safety and efficacy of SCB-2019 COVID vaccine candidate as a ChAdOx1-S booster

In a recent study posted to the medRxiv* pre-print server, researchers evaluated the immunogenicity of booster doses of alum-adjuvanted SCB-2019 vaccine candidate's three formulations.

6 Jun 2022

Recombinant protein vaccine stands up to SARS-CoV-2 variants

A study by researchers in Texas describes a mouse model in which a subunit vaccine with alum-CpG adjuvant was tested for its ability to induce a broadly neutralizing antibody response against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

18 May 2022

Only some coronaviruses found to have pandemic-causing potential

In a new study, scientists focused on resolving the mystery of why some coronaviruses have the potential of causing a pandemic while others do not.

18 May 2022

Study identifies cancer biomarkers based on a type of genetic modification

Biomarkers are often used during the management of cancer to guide treatment decisions and predict patient outcomes. However, it is often difficult to identify appropriate biomarkers that can be consistently reproduced and are easily analyzed with limited patient specimens.

18 May 2022

An assessment of COVID-19 vaccine safety during pregnancy

In a recent study posted to the Preprints with The Lancet* SSRN preprint server, researchers evaluated the safety of currently administered coronavirus disease 2019 (COVID-19) vaccines in child-bearing women.

7 Apr 2022

Phase 2 trial evaluates the safety and immunogenicity of two doses of the SARS-CoV-2 vaccine MVC-COV1901 in adolescents

A recent study evaluated the safety and immunogenicity of a COVID-19 vaccine in a phase II trial.

21 Mar 2022

Potential Covid-19 vaccine may offer an inexpensive, easy-to-store alternative to RNA vaccines

While many people in wealthier countries have been vaccinated against Covid-19, there is still a need for vaccination in much of the world.

16 Mar 2022

Current progress in SARS-CoV-2 vaccine candidates

In a new study, researchers illustrated the current progress and obstacles in COVID-19 vaccine development.

7 Mar 2022

The need for a holistic and unbiased approach to develop a more universal vaccine for coronaviruses

Researchers emphasized the need to take on a holistic and unbiased approach to develop a universal vaccine for coronaviruses, including SARS-CoV-2, which is a biomedical priority during the ongoing COVID-19 pandemic.

28 Feb 2022

Traditional Chinese medicine can be an effective radiosensitizer for patients with nasopharyngeal carcinoma

Treatment of nasopharyngeal carcinoma (NPC), a group of cancers that originate in the nose and throat, is made complicated by their unique position. Radiation therapy is often the main curative treatment for NPC. However, some patients are resistant to radiation therapy.

25 Feb 2022

Exploring the potential of mosaic RBD nanoparticles to fight SARS-CoV-2

Researchers explore the potential of mosaic receptor-binding domain nanoparticles in protective immunity against SARS-CoV-2

22 Feb 2022

Intranasal vaccine with nanoparticles offers strong protection against influenza viruses

An influenza vaccine administered through the nose and constructed with nanoparticles that enhance immune response offers strong protection against different influenza virus strains, according to researchers in the Institute for Biomedical Sciences at Georgia State University.

29 Jan 2022

New pathways responsible for hepatocellular carcinoma identified

Hepatocellular carcinoma (HCC) is the most common type of primary liver cancer. It is one of leading causes of cancer-related deaths globally, with more than 700,000 new cases and 600,000 estimated HCC deaths each year.

18 Jan 2022

Defensosomes can act as decoys to protect against SARS-CoV-2

In a new study, researchers from New York University have been examining the ability of defensosomes to combat SARS-CoV-2 infection.

22 Dec 2021

Booster shots improve CD8+ T cell response to SARS-CoV-2 in animal model

In a new study, published on the bioRxiv* preprint server, scientists showed in a mice model that three doses of the same synthetic peptide vaccine, eliciting an exclusive CD8+ T cell response against one SARS-CoV-2 Spike epitope, protected against lethal SARS-CoV-2 infection, in the absence of neutralizing antibodies. Researchers also showed that the third dose resulted in superior generation of effector-memory T cells in the circulation and tissue-resident memory T (TRM) cells.

20 Dec 2021

Epigenetic clocks have potential as biomarkers of COVID-19 vaccine responses

New findings have important implications for research into the impact of COVID-19 and the mRNA vaccination on epigenetic aging in the immune system.

7 Dec 2021

CpG News and Research

Facial recognition algorithms show genetic similarities in genetically unrelated look-alike humans

Assessing immunization capacity of vaccine platforms with DNA origami harboring SARS-CoV-2 receptor binding domain

Charged nanoparticles combined with a vaccine effective in eliminating melanoma tumors in mice

COVID-19 vaccination with bacterial peptide conjugated to receptor-binding domain elicits potent immune response

Safety and efficacy of SCB-2019 COVID vaccine candidate as a ChAdOx1-S booster

Recombinant protein vaccine stands up to SARS-CoV-2 variants

Only some coronaviruses found to have pandemic-causing potential

Study identifies cancer biomarkers based on a type of genetic modification

An assessment of COVID-19 vaccine safety during pregnancy

Phase 2 trial evaluates the safety and immunogenicity of two doses of the SARS-CoV-2 vaccine MVC-COV1901 in adolescents

Potential Covid-19 vaccine may offer an inexpensive, easy-to-store alternative to RNA vaccines

Current progress in SARS-CoV-2 vaccine candidates

The need for a holistic and unbiased approach to develop a more universal vaccine for coronaviruses

Traditional Chinese medicine can be an effective radiosensitizer for patients with nasopharyngeal carcinoma

Exploring the potential of mosaic RBD nanoparticles to fight SARS-CoV-2

Intranasal vaccine with nanoparticles offers strong protection against influenza viruses

New pathways responsible for hepatocellular carcinoma identified

Defensosomes can act as decoys to protect against SARS-CoV-2

Booster shots improve CD8+ T cell response to SARS-CoV-2 in animal model

Epigenetic clocks have potential as biomarkers of COVID-19 vaccine responses

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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