Cyclophosphamide News and Research

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Cyclophosphamide is a drug that is used to treat many types of cancer and is being studied in the treatment of other types of cancer. It is also used to treat some types of kidney disease in children. Cyclophosphamide attaches to DNA in cells and may kill cancer cells. It is a type of alkylating agent. Also called CTX and Cytoxan.

Cyclophosphamide is a synthetic alkylating agent chemically related to the nitrogen mustards with antineoplastic and immunosuppressive activities. In the liver, cyclophosphamide is converted to the active metabolites aldophosphamide and phosphoramide mustard, which bind to DNA, thereby inhibiting DNA replication and initiating cell death.
TESE surgical technique can help men with childhood cancer experience parenthood

TESE surgical technique can help men with childhood cancer experience parenthood

15 Mar 2011
New PTLD Guideline highlighted at NCCN Annual Conference

New PTLD Guideline highlighted at NCCN Annual Conference

14 Mar 2011
FDA approves BENLYSTA for active, autoantibody-positive systemic lupus erythematosus

FDA approves BENLYSTA for active, autoantibody-positive systemic lupus erythematosus

10 Mar 2011
Human Genome Sciences receives FDA approval for Benlysta to treat lupus

Human Genome Sciences receives FDA approval for Benlysta to treat lupus

9 Mar 2011
Solasia, ZIOPHARM enter license and collaboration agreement for darinaparsin product

Solasia, ZIOPHARM enter license and collaboration agreement for darinaparsin product

7 Mar 2011
Allos reaches SPA agreement with FDA for FOLOTYN Phase 3 trial in PTCL

Allos reaches SPA agreement with FDA for FOLOTYN Phase 3 trial in PTCL

4 Mar 2011
Less-toxic combination of immune-based drug and chemotherapy drug produce long-term remissions in CLL

Less-toxic combination of immune-based drug and chemotherapy drug produce long-term remissions in CLL

25 Feb 2011
Phase II results of VELCADE in patients with aggressive lymphoma published in Journal of Clinical Oncology

Phase II results of VELCADE in patients with aggressive lymphoma published in Journal of Clinical Oncology

5 Feb 2011
Amgen, Pfizer present Enbrel new trial results against psoriasis at 69th AAD meeting in New Orleans, LA

Amgen, Pfizer present Enbrel new trial results against psoriasis at 69th AAD meeting in New Orleans, LA

5 Feb 2011
Genentech, Biogen announce FDA approval of Rituxan to treat follicular lymphoma

Genentech, Biogen announce FDA approval of Rituxan to treat follicular lymphoma

28 Jan 2011
ZIOPHARM's darinaparsin receives EMA COMP orphan drug designation for treatment of peripheral T-cell lymphoma

ZIOPHARM's darinaparsin receives EMA COMP orphan drug designation for treatment of peripheral T-cell lymphoma

20 Jan 2011
FOLOTYN Phase 2 peripheral T-cell lymphoma study results published in Journal of Clinical Oncology

FOLOTYN Phase 2 peripheral T-cell lymphoma study results published in Journal of Clinical Oncology

20 Jan 2011
Intrexon Corporation, ZIOPHARM enter partnership to develop, commercialize DNA-based therapeutics

Intrexon Corporation, ZIOPHARM enter partnership to develop, commercialize DNA-based therapeutics

7 Jan 2011
Dosing initiated in combination Phase I study of palifosfamide with etoposide and cisplatin/carboplatin in SCLC

Dosing initiated in combination Phase I study of palifosfamide with etoposide and cisplatin/carboplatin in SCLC

29 Dec 2010
Response Genetics presents two gene expression analysis for personalized cancer tharapy selection

Response Genetics presents two gene expression analysis for personalized cancer tharapy selection

14 Dec 2010
GeparQuinto study data on bevacizumab plus chemotherapy in early breast cancer to be presented at 33rd CTRC-AACR

GeparQuinto study data on bevacizumab plus chemotherapy in early breast cancer to be presented at 33rd CTRC-AACR

13 Dec 2010
Xeloda may reduce recurrence of faster growing breast cancers: Study

Xeloda may reduce recurrence of faster growing breast cancers: Study

13 Dec 2010
Novelos NOV-002 demonstrates positive results in Phase 2 neoadjuvant breast cancer trial

Novelos NOV-002 demonstrates positive results in Phase 2 neoadjuvant breast cancer trial

13 Dec 2010
Researchers present Phase III study of neoadjuvant therapy with trastuzumab and lapatinib for early breast cancer

Researchers present Phase III study of neoadjuvant therapy with trastuzumab and lapatinib for early breast cancer

13 Dec 2010
Obesity is associated with worse outcomes in patients with ER-positive/HER2-negative disease

Obesity is associated with worse outcomes in patients with ER-positive/HER2-negative disease

10 Dec 2010

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