Cytokine News and Research

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Age, genetic disposition play important role in susceptibility to Lyme disease

People react very differently to an infection with the Borrelia bacterium that causes Lyme disease.

7 Nov 2016

TPU scientists developing bioactive coating for medical implants

A group of young scientists from Tomsk Polytechnic University are developing a bioactive coating for medical implants. Due to its properties, it will be able to "convince" the body not to reject the artificial bones and joints.

2 Nov 2016

Researchers identify protein linked to negative effects of senescence

Cellular senescence is a state in which normal healthy cells do not have the ability to divide. Senescence can occur when cancer-causing genes are activated in normal cells or when chemotherapy is used on cancer cells.

1 Nov 2016

Study identifies potential pathway to improve rate at which the body burns calories

Researchers say they have identified a potential pathway in our muscle tissue to improve the rate at which our bodies burn calories.

1 Nov 2016

Study sheds new insights on immune cells involved in fighting dengue virus infection

India suffers from the highest number of dengue infections in the world, but there are few studies, if any, to understand the immune cells involved in fighting the virus.

21 Oct 2016

Anti-inflammatory drugs may improve severity of depressive symptoms, study finds

Anti-inflammatory drugs similar to those used to treat conditions such as rheumatoid arthritis and psoriasis could in future be used to treat some cases of depression, concludes a review led by the University of Cambridge, which further implicates our immune system in mental health disorders.

18 Oct 2016

Penn researchers identify new immune system mechanism to fight against infections

The innate immune system serves as a first-line defense, responding to infections almost immediately after a pathogen makes its way into the body.

17 Oct 2016

Study suggests possibility for small molecule drug/antibody combinatorial therapy to treat neuroblastoma

A study by a multidisciplinary team of researchers from The Saban Research Institute of Children's Hospital Los Angeles sheds further light on the role of the cytokine TGFβ1 in the growth of neuroblastoma, and suggests the possibility for a small molecule drug/antibody combinatorial therapy to treat this cancer.

12 Oct 2016

Researchers describe novel host-oriented therapeutic approach for preventing lethal immune responses

Staphylococcal and streptococcal infections affect millions of individuals each year. They are a leading cause of sepsis and account for many cases of pneumonia and post-surgical infections.

8 Oct 2016

Can vitamin D reduce asthma attacks? An interview with Professor Adrian Martineau

In the past vitamin D was just thought to be important in regulating calcium homeostasis and bone health as vitamin D deficiency is best known for causing rickets in children and osteomalacia in adults.

4 Oct 2016

Research identifies potential treatment target for chemoresistant cancer cells

A team of researchers has discovered that chemoresistant lung cancer cells suppress immune functions and strengthen resistance to chemotherapy by producing interleukin-34 (IL-34)—a type of cytokine.

3 Oct 2016

Novel immunotherapy shows promise against AML in clinical trial

A new type of immunotherapy shows promise against cases of acute myeloid leukemia (AML) that recur after treatment or that never respond to therapy in the first place.

21 Sep 2016

VIB-Ghent University research provides insights into septic shock

Researchers at VIB and Ghent University have discovered an important mechanism of sepsis, an overreaction of the body's immune system to an infection.

14 Sep 2016

Right dose of CAR T cells and lymphodepletion can achieve good response rates for NHL patients

In a paper published today in Science Translational Medicine, researchers from Fred Hutchinson Cancer Research Center shared data from an early-phase study of patients with advanced non-Hodgkin lymphoma (NHL) who received JCAR014, a Chimeric Antigen Receptor (CAR) T cell treatment, and chemotherapy.

9 Sep 2016

Novel approach may help combat kidney disease in diabetic patients

A new strategy may help halt the progression of kidney disease in patients with diabetes.

9 Sep 2016

Fiocruz to start phase II clinical trials of novel vaccine for schistosomiasis

The Oswaldo Cruz Foundation at Rio de Janeiro, Brazil, will start the phase II clinical trials of a vaccine for schistosomiasis, called 'Sm14 Vaccine'.

26 Aug 2016

Research findings pave way to effective strategies for treatment of visceral leishmaniasis

A study shows that stimulating the production of interleukin-17A (IL-17A), one of the cytokines released by cells of the immune system, can be an effective strategy for the treatment of visceral leishmaniasis, considered one of the six most important parasitic diseases affecting humans.

25 Aug 2016