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Study reveals early death predictors in COVID-19 patients with cardiac injury

Announcing a new article publication for Cardiovascular Innovations and Applications journal. The activation of immune and thrombotic biomarkers at admission, and their ability to predict cardiac injury and mortality patterns in COVID-19, remains unclear.

26 Feb 2024

Natural killer cells lead the charge in cancer treatment innovation

Review synthesizes research on NK cells' role in cancer immunity and their potential in therapeutics through bioengineering, immune checkpoint inhibitors, and cell engagers, highlighting ongoing preclinical and clinical trials.

22 Feb 2024

Elevated IFN-γ levels linked to long COVID, study finds

Researchers find elevated IFN-γ levels in long COVID patients, with symptom improvement correlating with decreased IFN-γ, suggesting it as a potential biomarker and target for therapeutic intervention.

22 Feb 2024

MD Anderson acquires cell therapy safety technology from Bellicum Pharmaceuticals

The University of Texas MD Anderson Cancer Center today announced it has acquired certain assets from Bellicum Pharmaceuticals, Inc. related to the CaspaCIDe switch platform and the GoCAR platform.

22 Feb 2024

New study pinpoints key markers for Long COVID diagnosis

Study identifies elevated serologic responses and memory CD8+ T cell clonal expansion as key markers of Long COVID, offering insights into its pathology and potential diagnostic approaches.

18 Feb 2024

Smoking, infection, and BMI found to significantly sway immune response, study shows

Study reveals how smoking, CMV latent infection, and BMI significantly influence cytokine release, impacting immune response variability and potentially affecting disease risk.

14 Feb 2024

Black cumin: Ancient superseed with modern health benefits

Review discusses the multifaceted role of Nigella sativa in treating cardiometabolic diseases, highlighting its bioactive components like thymoquinone, which contribute to its antioxidant, anti-inflammatory, and anti-dyslipidemic properties.

13 Feb 2024

Mediterranean and vegetarian diets boost heart health by improving novel CVD markers

Study reveals that both lacto-ovo vegetarian and Mediterranean diets positively impact apolipoprotein levels and cardiovascular disease risk factors, with Mediterranean diet showing a more substantial effect on apolipoprotein levels, particularly in women and older individuals with fewer CVD risk factors.

13 Feb 2024

Cytokine interferon-gamma can be a disease-modifying therapeutic target in multiple system atrophy

Multiple system atrophy is a rare and fatal neurodegenerative disease, where insoluble inclusions of the protein alpha-synuclein appear in oligodendrocyte cells of the brain.

12 Feb 2024

Olive oil's secret weapon against Alzheimer's: phenolic compounds

A comprehensive review in the International Journal of Molecular Sciences highlights the potential of extra-virgin olive oil and its phenolic compounds in preventing and treating Alzheimer's disease through various mechanisms, including reducing amyloid-beta accumulation and neuroinflammation.

12 Feb 2024

Pregnant women show significant immune system changes linked to gut microbiome

How gut microbiota and metabolite changes relate to immune function during pregnancy.

12 Feb 2024

Hope for relapsed myeloma: Preclinical and clinical evidence for ruxolitinib's efficacy

A new research perspective was published in Oncotarget's Volume 15 on February 5, 2024, entitled, "Preclinical and clinical evaluation of the Janus Kinase inhibitor ruxolitinib in multiple myeloma."

8 Feb 2024

Monash-led study unveils potential long-term treatment for lupus

Researchers assessed Smith (Sm)-specific regulatory T cells (Tregs) efficacy in halting lupus nephritis (LN) by engineering and testing epitope-targeted Tregs for systemic lupus erythematosus (SLE) treatment.

8 Feb 2024

Study shines light on partial endothelial-to-mesenchymal transition in the tumor microenvironment

Endothelial-mesenchymal transition (EndoMT, also termed as EndMT), a biological process resulting in the formation of mesenchymal (or lineage-committed) phenotypes from endothelial cells (lining blood vessels), plays a crucial role in tumor progression.

7 Feb 2024

Gut microbiota alterations may influence immune system changes during pregnancy

During pregnancy, a woman's immune system changes dramatically but researchers don't yet understand all the underlying mechanisms.

7 Feb 2024

New cell therapy shows promise for critically ill COVID-19 patients with ARDS

Promising trial results indicate that a new type of cell therapy could improve the prognosis of those who are critically ill with acute respiratory distress syndrome (ARDS) resulting from severe Covid-19.

6 Feb 2024

SARS-CoV-2 fragments found to mimic immune system peptides, fueling inflammation

Study reveals SARS-CoV-2 fragments mimic immune peptides, potentially driving the virus's inflammatory response, offering insights into COVID-19's severe inflammation mechanisms.

5 Feb 2024

CRISPR-Cas9 gene-editing tool repairs defective T cells to treat rare hereditary disease

Some hereditary genetic defects cause an exaggerated immune response that can be fatal. Using the CRISPR-Cas9 gene-editing tool, such defects can be corrected, thus normalizing the immune response, as researchers led by Klaus Rajewsky from the Max Delbrück Center now report in "Science Immunology."

2 Feb 2024

Long COVID and ME/CFS share isimilarities in immune system dysfunction, study finds

A study led by UMass Chan Medical School viral immunologists Liisa Selin, MD, PhD, and Anna Gil, PhD, discovered similarities in immune system dysfunction as a potential biomarker among people living with long COVID and myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS).

1 Feb 2024

Circulatory cholesterol levels are inversely linked to mortality of patients with sepsis and critical illness

The association between biomarkers of cholesterol homeostasis and mortality in critically ill patients.

1 Feb 2024

Cytokine News and Research

Study reveals early death predictors in COVID-19 patients with cardiac injury

Natural killer cells lead the charge in cancer treatment innovation

Elevated IFN-γ levels linked to long COVID, study finds

MD Anderson acquires cell therapy safety technology from Bellicum Pharmaceuticals

New study pinpoints key markers for Long COVID diagnosis

Smoking, infection, and BMI found to significantly sway immune response, study shows

Black cumin: Ancient superseed with modern health benefits

Mediterranean and vegetarian diets boost heart health by improving novel CVD markers

Cytokine interferon-gamma can be a disease-modifying therapeutic target in multiple system atrophy

Olive oil's secret weapon against Alzheimer's: phenolic compounds

Pregnant women show significant immune system changes linked to gut microbiome

Hope for relapsed myeloma: Preclinical and clinical evidence for ruxolitinib's efficacy

Monash-led study unveils potential long-term treatment for lupus

Study shines light on partial endothelial-to-mesenchymal transition in the tumor microenvironment

Gut microbiota alterations may influence immune system changes during pregnancy

New cell therapy shows promise for critically ill COVID-19 patients with ARDS

SARS-CoV-2 fragments found to mimic immune system peptides, fueling inflammation

CRISPR-Cas9 gene-editing tool repairs defective T cells to treat rare hereditary disease

Long COVID and ME/CFS share isimilarities in immune system dysfunction, study finds

Circulatory cholesterol levels are inversely linked to mortality of patients with sepsis and critical illness

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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