Cytokines

Cytokine is a substance that is made by cells of the immune system. Some cytokines can boost the immune response and others can suppress it. Cytokines can also be made in the laboratory by recombinant DNA technology and used in the treatment of various diseases, including cancer.

What are Cytokines?

The term "cytokine" is derived from a combination of two Greek words - "cyto" meaning cell and "kinos" meaning movement. Cytokines are cell signalling molecules that aid cell to cell communication in immune responses and stimulate the movement of cells towards sites of inflammation, infection and trauma.

Cytokine Effects

Cytokine Nomenclature

Cytokine Classification

Cytokine Receptors

Inflammatory Cytokines and Depression

Latest Cytokines News and Research

Aging affects immune response and virus dynamics in COVID-19 patients, study finds

A study examining 1031 hospitalized COVID-19 patients found that aging significantly impacts immune responses, viral dynamics, and the nasal microbiome, with older adults experiencing more severe disease symptoms and delayed viral clearance.

18 Apr 2024

Breast milk's secret weapon against RSV revealed in new study

Researchers explored how human milk oligosaccharides (HMOs) protect infants from respiratory syncytial virus (RSV), suggesting that these components in breast milk may prevent or reduce the severity of RSV infections through multiple mechanisms including gut microbiome modulation and direct antiviral actions.

15 Apr 2024

Study reveals how SARS-CoV-2 hijacks lung cells to drive COVID-19 severity

Researchers identified how SARS-CoV-2 targets and manipulates specific lung cells, using innovative techniques to trace the virus's impact on the cells' gene expression, revealing insights into early COVID-19 pathogenesis.

14 Apr 2024

Research sheds light on post-sepsis immune suppression mechanism

Severe sepsis from bacterial or viral infections can be life-threatening and even people recovering from severe sepsis may experience long-lasting effects on the immune system, making them more susceptible to recurrent infections.

13 Apr 2024

Geraniol alleviates cognitive decline in D-galactose-induced aging mice

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 6, entitled, "Geraniol attenuates oxidative stress and neuroinflammation-mediated cognitive impairment in D galactose-induced mouse aging model."

12 Apr 2024

Treating gum disease during AFib blanking period could reduce recurrence risk

Study evaluates whether treating periodontitis during the blanking period after atrial fibrillation (AF) ablation reduces AF recurrence, revealing that comprehensive periodontal care may significantly diminish recurrence rates by addressing inflammation linked to periodontitis.

12 Apr 2024

Gut bacteria play a pivotal role in obesity's impact on body fat metabolism

Review explores the complex interplay between gut microbiota dysregulation in obesity and its impacts on white and brown adipose tissue metabolism, focusing on direct and indirect effects on mitochondria, highlighting potential avenues for obesity treatment through microbiota-focused strategies.

11 Apr 2024

Maternal influences on food allergy prevention: A closer look at diet and environment

Review assesses how maternal diet and environmental factors during pregnancy influence the prevention of food allergies in offspring, underlining the importance of a balanced diet and questioning the efficacy of allergen avoidance.

9 Apr 2024

The complex relationship between obesity and male reproductive function

Authors have analyzed current evidence on the impact of obesity on the male reproduction system.

9 Apr 2024

Gut-friendly psychobiotics could brighten moods and fight depression

Review uncovers that psychobiotics may offer supportive treatment for depression by restoring gut microbiome balance and positively influencing the microbiome-gut-brain axis, which is crucial for mental health and well-being.

8 Apr 2024

Interferon-beta deficiency alters brain response in neuroHIV mouse model

NeuroHIV refers to the effects of HIV infection on the brain or central nervous system and, to some extent, the spinal cord and peripheral nervous system.

4 Apr 2024

Study highlights anti-inflammatory properties of herbal medicine, Erigeron breviscapus to treat osteoarthritis

Researchers explored using Erigeron breviscapus (EB) as a treatment for osteoarthritis (OA).

4 Apr 2024

New technique reveals insights into gut cell dynamics during inflammation

Cells within the intestines perform various roles including nutrient absorption, sensing, and maintaining homeostasis.

2 Apr 2024

An ActRIIA fusion protein got FDA approved for PAH treatment

On March 26th, the US FDA granted approval for Merck’s WINREVAIR™ (sotatercept-csrk), marking a significant milestone in pulmonary arterial hypertension (PAH) treatment. PAH, characterized by elevated blood pressure in the arteries connecting the heart and lungs, poses a grave risk of heart failure.

From Sino Biological Inc. 28 Mar 2024

Dietary vitamin A shows promise in Alzheimer's disease intervention, study finds

Study explored the impact of dietary vitamin A on gut microbiota and intestinal transcriptome, revealing its potential in Alzheimer's disease (AD) pathology and cognitive functions in mice.

28 Mar 2024

New insights into the exacerbation of psoriasis through specific genetic defects

The inflammatory potential of tissue-resident regulatory T cells in a murine gain of function model.

27 Mar 2024

Study reveals trigonelline as a therapeutic agent for mitochondrial dysfunction in aging

Sarcopenia is the age-related decline in skeletal muscle due to the wasting of myofiber.

26 Mar 2024

Study suggests treating anxiety and depression significantly reduces ER visits and rehospitalizations among heart disease patients

A new study looks at this area in order to provide evidence for key recommendations in the treatment of such patients.

22 Mar 2024

Lactate's role in driving cancer cachexia uncovered

Study highlights the significant role of lactate in promoting cancer cachexia via activation of the adipose-specific G-protein-coupled receptor 81 (GPR81), suggesting new therapeutic targets for this condition.

20 Mar 2024

Exposure to high heat may increase inflammation and interfere with immune system functions

Short-term exposure to higher heat may increase inflammation and interfere with normal immune system functions in the body, which may, in turn, increase susceptibility to infections and accelerate the progression of cardiovascular disease, according to preliminary research to be presented at the American Heart Association's Epidemiology and Prevention│Lifestyle and Cardiometabolic Scientific Sessions 2024, March 18- 21, in Chicago.

19 Mar 2024