Cytomegalovirus News and Research

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Cytomegalovirus (CMV) is a member of the herpes virus group, which includes herpes simplex virus types 1 and 2, varicella-zoster virus (which causes chickenpox), and Epstein-Barr virus (which causes infectious mononucleosis). Infection with CMV is a major cause of disease and death in immunocompromised patients, including organ transplant recipients, patients undergoing hemodialysis, patients with cancer, patients receiving immunosuppressive drugs, and HIV-infected patients. While drugs are available for treatment of these conditions, the primary drug choices carry significant side effects and warnings. Currently, there are no anti-CMV drugs indicated for treatment of primary CMV infection during pregnancy resulting in infections that can have catastrophic consequences to the newborn. Maternal-fetal transfer of CMV infection results in a fetal death rate of 12% and most survivors have permanent debilitating disorders, including mental retardation, vision loss, and sensorineural deafness.

Further Reading

Autism antibodies are not genetically determined, as parents do not exhibit them

Autism antibodies are not genetically determined, as parents do not exhibit them

Discovery may explain why people with AIDS may suffer severe infections from viruses that they would otherwise defeat

Discovery may explain why people with AIDS may suffer severe infections from viruses that they would otherwise defeat

Treatment of cytomegalovirus remains a priority in order to improve the prognosis for people with HIV-1 infection

Treatment of cytomegalovirus remains a priority in order to improve the prognosis for people with HIV-1 infection

New findings may help better understand how harmless viruses can cause severe disease among patients with weakened immune systems

New findings may help better understand how harmless viruses can cause severe disease among patients with weakened immune systems

Women exposed in adulthood to cytomegalovirus may be at greater risk of breast cancer

Women exposed in adulthood to cytomegalovirus may be at greater risk of breast cancer

$3.5 million grant to develop AIDS vaccinations

$3.5 million grant to develop AIDS vaccinations

Intranasal influenza vaccine may help induce broader immunity in children than the traditional flu shot

Intranasal influenza vaccine may help induce broader immunity in children than the traditional flu shot

CellCept linked to reduced cancer incidence

CellCept linked to reduced cancer incidence

Novel vaccine technology to suppress the growth of certain tumors

Novel vaccine technology to suppress the growth of certain tumors