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Researchers investigate SARS-CoV-2 specific inflammatory response

New research can confirm that while some of the response from monocytes to SARS-CoV-2 is generic to virus infection, most of it SARS-CoV-2 specific, especially proinflammatory responses.

7 Jan 2022

Researchers explore novel strategy to improve the reprogramming efficiency of human fibroblasts

Not too long ago the idea of taking, for instance a skin cell and transforming it into a muscle cell was unthinkable. About 10 years ago, however, revolutionary research showed that it is indeed possible to reprogram differentiated adult cells into other types fully capable of conducting new functions.

6 Jan 2022

After SARS-CoV-2 booster dose memory B cells adapt to Omicron

Memory B cells never forget recurrent viral exposures and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is no exception, according to a new medRxiv* preprint study.

5 Jan 2022

Production of molecular probes of spike and subdomains for all SARS-CoV-2 variants

Researchers designed molecular probes of diverse SARS-CoV-2 variants and evaluated their antibody binding specificity.

3 Jan 2022

T-cell responses to SARS-CoV-2 Omicron variant confer protection to vaccinated individuals

Researchers ascertain whether the SARS-CoV-2 Omicron variant evades cellular immunity.

3 Jan 2022

Researchers investigate the effect of emerging SARS-CoV-2 mutations on ACE2 binding

Now in new research, scientists from the University of Leicester have been investigating how these mutations alter the affinities of RBDs to ACE2.

28 Dec 2021

Study hints subtle differences in the quality of immune response based on COVID-19 severity

Infection-fighting B cells retain better memory of the coronavirus spike protein in University Hospital patients who recover from less-severe cases of COVID-19 than in those recovering from severe COVID-19, a new study suggests.

24 Dec 2021

Importance of booster vaccine doses for maintaining protection against the SARS-CoV-2 Omicron variant

A new study shows that although the Omicron variant exhibits significant immune escape compared to other SARS-CoV-2 variants, antibody neutralization can be largely restored with booster doses of mRNA vaccines.

22 Dec 2021

Defensosomes can act as decoys to protect against SARS-CoV-2

In a new study, researchers from New York University have been examining the ability of defensosomes to combat SARS-CoV-2 infection.

22 Dec 2021

Molecular mechanism of SARS-Cov-2-induced thrombosis

Researchers demonstrate that the exposure of platelets to the SARS-CoV-2 spike protein promotes their activation and adhesion.

21 Dec 2021

Severe COVID-19 found to be associated with disrupted intestinal Peyer’s patches

A new study demonstrates significantly altered structure and cellularity of Peyer’s patches in deceased COVID-19 patients.

21 Dec 2021

Booster shots improve CD8+ T cell response to SARS-CoV-2 in animal model

In a new study, published on the bioRxiv* preprint server, scientists showed in a mice model that three doses of the same synthetic peptide vaccine, eliciting an exclusive CD8+ T cell response against one SARS-CoV-2 Spike epitope, protected against lethal SARS-CoV-2 infection, in the absence of neutralizing antibodies. Researchers also showed that the third dose resulted in superior generation of effector-memory T cells in the circulation and tissue-resident memory T (TRM) cells.

20 Dec 2021

Cytometry News and Research

Researchers investigate SARS-CoV-2 specific inflammatory response

Researchers explore novel strategy to improve the reprogramming efficiency of human fibroblasts

After SARS-CoV-2 booster dose memory B cells adapt to Omicron

Production of molecular probes of spike and subdomains for all SARS-CoV-2 variants

T-cell responses to SARS-CoV-2 Omicron variant confer protection to vaccinated individuals

Researchers investigate the effect of emerging SARS-CoV-2 mutations on ACE2 binding

Study hints subtle differences in the quality of immune response based on COVID-19 severity

Importance of booster vaccine doses for maintaining protection against the SARS-CoV-2 Omicron variant

Defensosomes can act as decoys to protect against SARS-CoV-2

Molecular mechanism of SARS-Cov-2-induced thrombosis

Severe COVID-19 found to be associated with disrupted intestinal Peyer’s patches

Booster shots improve CD8+ T cell response to SARS-CoV-2 in animal model

Lung memory B-cells provide primary protection against SARS-CoV-2 reinfection

Reduced antibody-mediated neutralization by the SARS-CoV-2 Omicron variant

Cell surface expression of SARS-CoV-2 nucleocapsid protein and its role in immunity

Omicron evades immunity more than other SARS-CoV-2 variants

New mRNA vaccine platform provides stronger protection against SARS-CoV-2 delta variant

Novel immunotherapy shows promise for children, young adults with recurrent AML

Infant immune system beats the adult immune system at fighting off new pathogens

Immune responses against SARS-CoV-2 Delta variant after BNT162b2 vaccination in people living with HIV

Flow Cytometry eBook

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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