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SARS-CoV-2 BA.1 and BA.2 breakthrough infections likely protect against BA.4 infection

Omicron BTIs induce durable neutralizing immune responses by recalling cross-reactive and vaccine-induced memory B lymphocytes.

1 Mar 2023

Study reveals synergistic impact of estrogen and intestinal dysbiosis on pulmonary fibrosis

In a recent study published in Cells, researchers evaluated idiopathic pulmonary fibrosis (IPF) pathophysiological differences by sex and intestinal microbiome.

1 Mar 2023

Critical COVID-19 infection characterized by a shift from naïve T cell phenotypes to an expansion of cytotoxic CD4+ T lymphocyte subsets

Researchers immunophenotyped T lymphocyte responses among unvaccinated individuals, representative of the entire spectrum of the clinical presentation of COVID-19.

28 Feb 2023

Study supports the concept of atherosclerosis as a T-cell autoimmune disease targeting the arterial wall

Researchers assessed T-cell tolerance checkpoints observed in atherosclerosis.

27 Feb 2023

NQO2 gene as a novel potential target in Parkinson’s disease

A new study under review at the journal Scientific Reports and currently available on the Research Square* preprint server aimed to analyze the toxic effects of 6OHDA along with a related role of NQO2 in murine and human astrocytes.

23 Feb 2023

Study indicates that macrophages that reside in the lymph nodes contribute to the initial Zika virus spread

Researchers mapped Zika virus infections in the lymph nodes to determine how the Zika virus enters from different points in the skin and disseminates through the body.

20 Feb 2023

Jamaican fruit bat's response to SARS-CoV-2 adapted to human

In a recent study posted to the bioRxiv* server, researchers examined the vulnerability of Jamaican fruit bats (Artibeus jamaicensis) to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

15 Feb 2023

Whole-genome CRISPR activation for the identification of host factors controlling cellular interactions with SARS-CoV-2

Researchers found that LRRC15, a TLR-related cell surface receptor, blocked SARS-CoV-2 spike binding.

13 Feb 2023

Casein-based diet found to protect diabetic mice against autoimmunity

Researchers studied diet-commensal microbial interactions in autoimmunity.

10 Feb 2023

Cellular and humoral responses and the safety of recombinant and inactivated SARS-CoV-2 vaccines in chronic kidney disease patients

Researchers investigated the B cell and humoral immune responses elicited against inactivated and recombinant SARS-CoV-2 vaccines and their safety profiles in patients with CKD.

8 Feb 2023

Proteomics reveals a distinct IFN-driven plasma cytokine response to COVID-19 in infants and young children

Researchers assesses immune responses to SARS-CoV-2 shortly after birth using a multi-omics approach.

5 Feb 2023

Researchers report a heterologous vaccination strategy against IBV in Chickens

Researchers reported on the immunogenicity of a heterologous vaccine regimen against IBV, comprising prime doses of QAC-encapsulated plasmid and a booster dose of MVA.

2 Feb 2023

New study suggests Omicron BA.1 breakthrough infection drives long-term remodeling of memory B cell repertoire in vaccinated populations

A recent study posted on the bioRxiv* preprint server has longitudinally characterized the MBC repertoire and humoral response after Omicron BA.1 breakthrough infection in individuals vaccinated with the COVID-19 mRNA vaccine.

1 Feb 2023

Researchers devise a novel potential IBD treatment strategy that eliminates pathogenic T cells and encourages the proliferation of regulatory T cells

Researchers investigated the CAMCI strategy as an immunotherapeutic option for inflammatory bowel disease.

31 Jan 2023

Study finds link between tumor microbiome and immune system in sarcoma patients

In a significant new study, UC Davis Comprehensive Cancer Center researchers have uncovered a link between a patient's microbiome and their immune system that can potentially be used to improve the treatment of soft tissue sarcoma.

30 Jan 2023

Children's tonsils are major sites of prolonged SARS-CoV-2 infection

A recent study evaluates the presence of SARS-CoV-2 in children’s tonsils during the COVID-19 pandemic.

29 Jan 2023

Combination of targeted therapies with immunotherapy addresses treatment resistance in pancreatic cancer

A team of investigators at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine has shown for the first time that a combination of targeted therapies with immunotherapy addresses one of the major reasons pancreatic cancer is so notoriously treatment resistant.

26 Jan 2023

Researchers use multiplexed 3D imaging to perform molecular and morphological assessments of colorectal cancers

Researchers used multiplexed and three-dimensional imaging with machine-based learning and spatial statistics to perform molecular and morphological assessments of colorectal cancers (CRC).

24 Jan 2023

Researchers discover the gene responsible for radiation resistance in mutant IDH1 glioma

It's a good news, bad news story. Patients whose brain tumors have a mutated enzyme called IDH1 typically live longer than those without the mutation.

24 Jan 2023

Researchers identify potent pan-sarbecovirus antibodies from non-human primates vaccinated with an AS03 adjuvanted subunit SARS-CoV-2 vaccine

Researchers assessed the effectiveness of pan-sarbecovirus-neutralizing antibodies against SARS-CoV-2.

24 Jan 2023

Cytometry News and Research

SARS-CoV-2 BA.1 and BA.2 breakthrough infections likely protect against BA.4 infection

Study reveals synergistic impact of estrogen and intestinal dysbiosis on pulmonary fibrosis

Critical COVID-19 infection characterized by a shift from naïve T cell phenotypes to an expansion of cytotoxic CD4+ T lymphocyte subsets

Study supports the concept of atherosclerosis as a T-cell autoimmune disease targeting the arterial wall

NQO2 gene as a novel potential target in Parkinson’s disease

Study indicates that macrophages that reside in the lymph nodes contribute to the initial Zika virus spread

Jamaican fruit bat's response to SARS-CoV-2 adapted to human

Whole-genome CRISPR activation for the identification of host factors controlling cellular interactions with SARS-CoV-2

Casein-based diet found to protect diabetic mice against autoimmunity

Cellular and humoral responses and the safety of recombinant and inactivated SARS-CoV-2 vaccines in chronic kidney disease patients

Proteomics reveals a distinct IFN-driven plasma cytokine response to COVID-19 in infants and young children

Researchers report a heterologous vaccination strategy against IBV in Chickens

New study suggests Omicron BA.1 breakthrough infection drives long-term remodeling of memory B cell repertoire in vaccinated populations

Researchers devise a novel potential IBD treatment strategy that eliminates pathogenic T cells and encourages the proliferation of regulatory T cells

Study finds link between tumor microbiome and immune system in sarcoma patients

Children's tonsils are major sites of prolonged SARS-CoV-2 infection

Combination of targeted therapies with immunotherapy addresses treatment resistance in pancreatic cancer

Researchers use multiplexed 3D imaging to perform molecular and morphological assessments of colorectal cancers

Researchers discover the gene responsible for radiation resistance in mutant IDH1 glioma

Researchers identify potent pan-sarbecovirus antibodies from non-human primates vaccinated with an AS03 adjuvanted subunit SARS-CoV-2 vaccine

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Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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