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Novogen partners with Genea Biocells to accelerate testing for neurodegenerative diseases

Novogen Limited, an oncology drug development company, today announced a collaboration with Australian company, Genea Biocells, to accelerate testing of their super-benzopyran (SBP) drugs for degenerative diseases of the nervous system and muscles.

5 May 2014

Researcher to recieve 2014 EMBO Gold Medal at FEBS-EMBO Meeting

EMBO today announced Sophie Martin of the University of Lausanne, Switzerland, as the winner of the 2014 EMBO Gold Medal. The award acknowledges her work to understand the molecular events that define the organization and development of the cell.

25 Apr 2014

Study provides better understanding of intestinal pathologies associated with inherited, infectious diseases

The "brush border" - a densely packed array of finger-like projections called microvilli - covers the surfaces of the cells that line our intestines.

17 Apr 2014

Study proposes new model for understanding how proteins bind together to facilitate cell movement

Cell movement plays an important role in a host of biological functions from embryonic development to repairing wounded tissue. It also enables cancer cells to break free from their sites of origin and migrate throughout the body.

17 Apr 2014

Researchers reveal how cells respond to mechanical manipulation

The push and pull of physical force can cause profound changes in the behavior of a cell. Two studies from researchers working at the UNC Lineberger Comprehensive Cancer Center reveal how cells respond to mechanical manipulation

10 Apr 2014

Research finding sheds more light on cancer development and metastasis

10 Apr 2014

Study uncovers one way that p53 acts to prevent cancer cell invasion

The tumor suppressor p53 does all it can to prevent oncogenes from transforming normal cells into tumor cells by killing defective cells or causing them to become inactive.

25 Mar 2014

Scientists discover new protein that drive metastasis of cancer cells

An international team of researchers led by scientists at The Wistar Institute have discovered and defined LIMD2, a protein that can drive metastasis, the process where tumors spread throughout the body.

11 Mar 2014

Rare and de novo mutations flesh out schizophrenia picture

Two studies in Nature show that rare disruptive and de novo mutations may contribute to the pathophysiology of schizophrenia.

6 Feb 2014

Extracts from birch tree helps damaged skin around wounds to regenerate more quickly

Extracts from the birch tree have served for centuries as a traditional means of helping the damaged skin around wounds to regenerate more quickly. Prof. Dr. Irmgard Merfort from the Institute of Pharmaceutical Sciences of the University of Freiburg and her team have now explained the molecular mechanism behind the wound-healing effect of an extract from the outer white layer of the tree's bark.

24 Jan 2014

Researcher reveals how temperature impacts development of embryos

In nature, animals face a broad range of temperatures, and at times the heat can become taxing. When it becomes too hot to survive, some animals can simply migrate to more favorable climates, but what if you are a mere embryo confined within an egg and cannot escape the heat?

6 Jan 2014

Acetylon Pharmaceuticals presents positive interim data from two ricolinostat clinical trials at ASH 2013

Acetylon Pharmaceuticals, Inc., the leader in the development of selective histone deacetylase inhibitors for enhanced therapeutic outcomes, today announced that positive interim clinical data from the two proof-of-concept clinical trials with selective HDAC6 inhibitor, ricolinostat (ACY-1215), were presented at the 55th Annual Meeting of the American Society of Hematology in New Orleans, LA.

9 Dec 2013

Research: Motor proteins transport mRNA to get where it is needed, prevent diseases

Scientists have found that mRNA may travel one way down a cell, then board another, aptly named motor protein, and head in the opposite direction to get where it ultimately needs to be.

27 Nov 2013

MGH investigators identify molecule that plays key role in the breakdown of kidney filter

One of the most devastating side effects of diabetes is kidney failure, and one of the earliest signs of kidney damage is a disruption of the organ's filtering capacity. Diabetes patients who develop kidney failure must go on dialysis, seriously limiting their quality of life and placing them at significantly increased risk of death. The incidence of kidney disease is increasing with rising rates of obesity-associated type 2 diabetes, but very little progress has been made towards protecting the kidney's filter barrier during the past 50 years.

16 Nov 2013

Study reveals that specific protein may assist breast cancer cells in metastasizing

A new study by University of Kentucky Markey Cancer Center researchers Min Chen and Kathleen O'Connor shows that a specific protein may assist breast cancer cells in metastasizing.

29 Oct 2013

Discovery sheds light on how forces outside of cells get translated into internal signals

Johns Hopkins researchers used suction to learn that individual "molecular muscles" within cells respond to different types of force, a finding that may explain how cells "feel" the environment and appropriately adapt their shapes and activities.

21 Oct 2013

Clarified role of signal-relay proteins may help explain spread of cancer

Cell biologists at The Johns Hopkins University have teased apart two integral components of the machinery that causes cells to move. Their discovery shows that cellular projections, which act as hands to help a cell "crawl," are apparently always initiated by a network of message-relaying proteins inside the cell.

21 Oct 2013

Researchers define role of vinculin protein in enabling cell mobility

Researchers at the University of North Carolina and the National Institutes for Health have defined the role of the protein vinculin in enabling cell movement.

16 Aug 2013

Osteoarthritis research: an interview with Dr Deborah Mason, Cardiff University

Osteoarthritis is an extremely common condition affecting about 8 million people in the UK. The elderly are particularly susceptible, with up to 45% of people over 65 years, having the disease.

14 Aug 2013

Research couple receives 2013 Khalid Iqbal Lifetime Achievement Award for Alzheimer's study

The research couple receives the "2013 Khalid Iqbal Lifetime Achievement Award" for its role as pioneers in investigating the role of tau in Alzheimer's disease. The award ceremony was held yesterday (10:45 am US EST) within the framework of the "Alzheimer's Association International Conference (AAIC 2013)" in Boston (USA).

17 Jul 2013