DNA Methylation News and Research

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DNA methylation is a type of chemical modification of DNA that can be inherited and subsequently removed without changing the original DNA sequence. As such, it is part of the epigenetic code and is also the most well characterized epigenetic mechanism.

Newest vitamin B3 family member has beneficial effects on mitochondria in the human muscle

The newest vitamin B3 family member, nicotinamide riboside (NR) has been found to have beneficial effects on mitochondria in the human muscle.

8 Feb 2023

A high-throughput screening assay for small molecule inhibitors of the antigen aminopeptidase ERAP1

The January 2023 issue of SLAS Discovery contains a collection of four full-length articles and one technical brief covering cancer research, high-throughput screening (HTS) assay development and other drug discovery exploration.

27 Jan 2023

Researchers review the association between endogenous retrovirus reactivation and aging

Researchers explored the role of endogenous retrovirus (ERV) reactivation in the aging process.

24 Jan 2023

Immunological interactions between asthma, obesity, and the microbiota

This study summarizes the mechanisms associated with obesity-aggravated asthma.

18 Jan 2023

Research explores the utility of epigenetically predicted BMI

DNA methylation is an accurate predictor of current BMI and a poor predictor of future BMI.

18 Jan 2023

Epigenetic alternations associated with common genital malformation in male babies

An alarming increase in the occurrence of the most common genital malformation in male babies, hypospadias, is likely due to environmental factors, such as toxicant exposure, which alter epigenetic programming in a forming penis.

18 Jan 2023

The loss of epigenetic information accelerates the aging process

A new study in the journal Cell aimed to determine whether epigenetic changes are a cause of mammalian aging.

15 Jan 2023

Unique mass spectrometry-based approach to study specific changes in DNA after replication

A new method to study specific changes in DNA after replication has been published as a technical report in Nature Cell Biology.

12 Jan 2023

What is the association between acute lymphoblastic leukemia and congenital cytomegalovirus infection?

Researchers evaluated the relationship between congenital cytomegalovirus (cCMV) infection and acute lymphoblastic leukemia (ALL).

11 Jan 2023

Study links epigenetic biological aging and aberrations in neural oscillatory activity in people with HIV

A new research paper was published in Aging (listed as "Aging (Albany NY)" by MEDLINE/PubMed and "Aging-US" by Web of Science) Volume 14, Issue 24, entitled, "Epigenetic aging is associated with aberrant neural oscillatory dynamics serving visuospatial processing in people with HIV."

6 Jan 2023

'Epigenetic fingerprints' of prenatal alcohol exposure could be biomarkers to detect developmental disorders

Alcohol exposure in early pregnancy can change gene function during the tightly regulated embryonic development, and consequently cause developmental disorders - especially neurodevelopmental disorders.

3 Jan 2023

DNAm measures of biological aging linked with neuropsychologically-validated cognitive decline in midlife

A new research paper was published in Aging (listed as "Aging (Albany NY)" by MEDLINE/PubMed and "Aging-US" by Web of Science) Volume 14, Issue 23, entitled, "DNA methylation-based measures of biological aging and cognitive decline over 16-years: preliminary longitudinal findings in midlife."

30 Dec 2022

Impact of epigenetics on the clinical management of cancer patients

Dr. Manel Esteller and Dr. Verónica Dávalos, researchers at the Josep Carreras Leukaemia Research Institute, describe in a new article the impact of epigenetics on cancer treatment and how it has become a crucial tool to improve early detection, predict disease progression and become a target for new treatments.

22 Dec 2022

Consistent exercise linked to beneficial epigenetic changes, twin-study shows

Consistent exercise can change not just waistlines but the very molecules in the human body that influence how genes behave, a new study of twins indicates.

6 Dec 2022

Colorectal cancer doesn’t wait - DNA methylation tests facilitate earlier treatment

In this interview, Yantao Li and Zhe Wang, Director of Cancer Early Screening Products and the Product Director of Oncology at BGI Genomics, talks to NewsMedical about colorectal cancer (CRC), including why incidences are important and the importance of screening.

From BGI Genomics 6 Dec 2022

AI tool can reliably classify difficult-to-diagnose nasal cavity tumors

Although tumors in the nasal cavity and the paranasal sinus are confined to a small space, they encompass a very broad spectrum with many tumor types.

29 Nov 2022

What genes are associated with asthma exacerbations?

In a new study, researchers reviewed the genomics, transcriptomics, and epigenetics of asthma exacerbations (AEs).

29 Nov 2022

Unique resource for identifying new biomarkers of environmental exposures in early life

Researchers now have a unique resource for identifying new biomarkers of environmental exposures in early life and understanding their health effects.

22 Nov 2022

Study shows biological link between muscle weakness and acceleration in biological age

Everyone ages at a different pace. That's why two 50-year-olds, despite living the same number of years, may have different biological ages – meaning that a host of intrinsic and extrinsic factors have caused them to age at varying paces with different levels of risk for disease and early death.

10 Nov 2022

The epigenetic alterations of monocytes in severe COVID-19

Researchers performed DNA methylation analysis on monocytes in the peripheral blood samples obtained from severe COVID-19 patients.

28 Oct 2022

DNA Methylation News and Research

Further Reading

Newest vitamin B3 family member has beneficial effects on mitochondria in the human muscle

A high-throughput screening assay for small molecule inhibitors of the antigen aminopeptidase ERAP1

Researchers review the association between endogenous retrovirus reactivation and aging

Immunological interactions between asthma, obesity, and the microbiota

Research explores the utility of epigenetically predicted BMI

Epigenetic alternations associated with common genital malformation in male babies

The loss of epigenetic information accelerates the aging process

Unique mass spectrometry-based approach to study specific changes in DNA after replication

What is the association between acute lymphoblastic leukemia and congenital cytomegalovirus infection?

Study links epigenetic biological aging and aberrations in neural oscillatory activity in people with HIV

'Epigenetic fingerprints' of prenatal alcohol exposure could be biomarkers to detect developmental disorders

DNAm measures of biological aging linked with neuropsychologically-validated cognitive decline in midlife

Impact of epigenetics on the clinical management of cancer patients

Consistent exercise linked to beneficial epigenetic changes, twin-study shows

Colorectal cancer doesn’t wait - DNA methylation tests facilitate earlier treatment

AI tool can reliably classify difficult-to-diagnose nasal cavity tumors

What genes are associated with asthma exacerbations?

Unique resource for identifying new biomarkers of environmental exposures in early life

Study shows biological link between muscle weakness and acceleration in biological age

The epigenetic alterations of monocytes in severe COVID-19

DNA Methylation eBook

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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