DNA Methylation News and Research

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DNA methylation is a type of chemical modification of DNA that can be inherited and subsequently removed without changing the original DNA sequence. As such, it is part of the epigenetic code and is also the most well characterized epigenetic mechanism.

Exploring epigenetic modifications and the use of vitamin D therapy in COVID-19

Researchers examined the role of epigenetic modifications of the host cell gene expression in determining the pathophysiology of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and explored the use of vitamin D as a therapeutic agent against coronavirus disease 2019 (COVID-19).

19 Oct 2022

Epigenetic changes related to Parkinson's disease are different in men and women, study says

The epigenetic changes linked to Parkinson's disease – a nervous system disorder that afflicts nearly 1 million Americans – are different in men and women, according to a new Rutgers study published in NPJ Parkinson's Disease.

18 Oct 2022

Study offers new insights into other melanomas not caused by the effects of UV radiation

A group of researchers based in Brazil and France have managed to discover markers left by exposure to sunlight in the genomes of people who suffer from cutaneous melanoma.

11 Oct 2022

Men are biologically older than women, study finds

A study at the University of Jyväskylä found that men are biologically older than women. The observed sex difference is partially explained by men's more frequent smoking and larger body size.

10 Oct 2022

Veterans with PTSD and other psychiatric disorders are at greater risk for early death

Psychiatric symptoms and diagnoses increase risk for premature morbidity and mortality. Now a new study has found that trauma-exposed Veterans with post-traumatic stress disorder and externalizing psychiatric disorders, like substance use disorders and antisocial personality disorder, are at greater risk for early death.

26 Sep 2022

Research brings us closer to optimizing treatments for children with retinoblastoma

Retinoblastoma is a cancer of the eye that occurs in infants and toddlers and can lead to loss of vision, loss of one or both eyes, and even death.

26 Sep 2022

A good night's sleep promotes immunity

In a recent study published in the Journal of Experimental Medicine, researchers in the United States used mice models to understand how sleep fragmentation affects immunological responses and the epigenetic modifications of hematopoietic stem and progenitor cells (HSPCs). They also conducted a sleep restriction trial in humans to determine HPSC programming and hematopoiesis.

25 Sep 2022

UCLA scientists receive $10 million to shed light on the developing brain's cellular infrastructure

Two scientists at the David Geffen School of Medicine at UCLA have been awarded nearly $10 million from the National Institutes of Health's Brain Research Through Advancing Innovative Neurotechnologies (BRAIN) Initiative for research projects that aim to shed light on the developing brain's cellular infrastructure to better understand brain disorders.

22 Sep 2022

Salk scientists launch a new Center for Multiomic Human Brain Cell Atlas with $126 million NIH grant

With a five-year, $126 million grant from the National Institutes of Health, a team led by Salk Institute scientists has launched a new Center for Multiomic Human Brain Cell Atlas.

22 Sep 2022

The effect of cannabis exposure on the entire sperm DNA methylome in rats

A new study examines how cannabis use among men could cause heritable effects on male fertility.

14 Sep 2022

Final results of the PATHFINDER study by GRAIL on multi-cancer early detection tests announced

A new press release announced the results of their interventional PATHFINDER study on the early detection of cancer using multi-cancer early detection (MCED) blood tests.

13 Sep 2022

Prenatal exposure to air pollution increases risk of childhood allergic rhinitis and asthma

In a recent study published in the Journal of Allergy and Clinical Immunology, researchers assessed the impact of prenatal exposure to air pollution on immune perturbations.

8 Sep 2022

Low-dose ketamine is safe and effective to treat children with ADNP syndrome, study suggests

Results of a small, but unique research study, led by researchers from the Seaver Autism Center for Research and Treatment at Mount Sinai and published online in Human Genetics and Genomic Advances, suggest that low-dose ketamine is generally safe, well-tolerated and effective to treat clinical symptoms in children diagnosed with ADNP syndrome (also known as Helsmoortel-VanDerAa syndrome), a rare neurodevelopmental disorder caused by mutations in the activity dependent neuroprotective protein (ADNP) gene.

6 Sep 2022

DNA Methylation News and Research

Further Reading

Exploring epigenetic modifications and the use of vitamin D therapy in COVID-19

Epigenetic changes related to Parkinson's disease are different in men and women, study says

Study offers new insights into other melanomas not caused by the effects of UV radiation

Men are biologically older than women, study finds

Veterans with PTSD and other psychiatric disorders are at greater risk for early death

Research brings us closer to optimizing treatments for children with retinoblastoma

A good night's sleep promotes immunity

UCLA scientists receive $10 million to shed light on the developing brain's cellular infrastructure

Salk scientists launch a new Center for Multiomic Human Brain Cell Atlas with $126 million NIH grant

The effect of cannabis exposure on the entire sperm DNA methylome in rats

Final results of the PATHFINDER study by GRAIL on multi-cancer early detection tests announced

Prenatal exposure to air pollution increases risk of childhood allergic rhinitis and asthma

Low-dose ketamine is safe and effective to treat children with ADNP syndrome, study suggests

Facial recognition algorithms show genetic similarities in genetically unrelated look-alike humans

Strong facial similarity in people is linked with shared genetic variants

BCG vaccine produces a "trained immunity response" which lasts more than a year

Elevated insulin resistance, advanced cell aging associated with childhood poverty

Tissue nanotransfection technology can serve as a non-viral, topical, gene-editing delivery device, research shows

New high-throughput genomic array offers an in-depth view of the mouse epigenome

Damon Runyon Cancer Research Foundation names five new Damon Runyon Clinical Investigators

DNA Methylation eBook

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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