DNA Replication News and Research

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DNA replication, the basis for biological inheritance, is a fundamental process occurring in all living organisms to copy their DNA. This process is "semiconservative" in that each strand of the original double-stranded DNA molecule serves as template for the reproduction of the complementary strand. Hence, following DNA replication, two identical DNA molecules have been produced from a single double-stranded DNA molecule. Cellular proofreading and error-checking mechanisms ensure near perfect fidelity for DNA replication.
Study shows R9-caPep compound blocks PCNA actions in neuroblastoma cells

Study shows R9-caPep compound blocks PCNA actions in neuroblastoma cells

Protein expression predicts postop NSCLC recurrence, survival

Protein expression predicts postop NSCLC recurrence, survival

Scientists uncover surprising link between brain development and gene tied to breast cancer

Scientists uncover surprising link between brain development and gene tied to breast cancer

Stowers team reports genome-wide analysis of genes that drive cell division in multicellular organism

Stowers team reports genome-wide analysis of genes that drive cell division in multicellular organism

Researchers discover protein for treatment of anaplastic thyroid carcinoma

Researchers discover protein for treatment of anaplastic thyroid carcinoma

NUS researchers discover promising treatment for anaplastic thyroid carcinoma

NUS researchers discover promising treatment for anaplastic thyroid carcinoma

Researchers detail how psoralen blocks signaling pathway of HER2-positive cancers

Researchers detail how psoralen blocks signaling pathway of HER2-positive cancers

Pfizer’s palbociclib Phase 2 trial achieves primary endpoint in patients with advanced breast cancer

Pfizer’s palbociclib Phase 2 trial achieves primary endpoint in patients with advanced breast cancer

International study develops refined method to identify individuals at risk for certain inherited cancer

International study develops refined method to identify individuals at risk for certain inherited cancer

Activation of protein P300 plays central role in DNA repair in hippocampal neurons

Activation of protein P300 plays central role in DNA repair in hippocampal neurons

Scientists unveil novel piece of puzzle of cancer cell DNA repair mechanisms

Scientists unveil novel piece of puzzle of cancer cell DNA repair mechanisms

Researchers discover new human enzyme that facilitates DNA repair during DNA copying process

Researchers discover new human enzyme that facilitates DNA repair during DNA copying process

A*STAR scientists discover potential target to weed out progression of cancer

A*STAR scientists discover potential target to weed out progression of cancer

Research findings could offer new insights into how defective cells can multiply in diseases

Research findings could offer new insights into how defective cells can multiply in diseases

Gene mutation offers clues to development of diverse neurological disorders

Gene mutation offers clues to development of diverse neurological disorders

New research explains how DNA strands repair themselves

New research explains how DNA strands repair themselves

Study: Changes in expression of various isoforms might play role in cancer development

Study: Changes in expression of various isoforms might play role in cancer development

Researchers discover role played by epigenetic factors in senescence and age-related diseases

Researchers discover role played by epigenetic factors in senescence and age-related diseases

Michigan researchers use TACC supercomputers to understand DNA bending, repair mechanisms

Michigan researchers use TACC supercomputers to understand DNA bending, repair mechanisms