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Research reveals molecular clues associated with traumatic brain injury

New research led by scientists at Arizona State University has revealed some of the first detailed molecular clues associated with one of the leading causes of death and disability, a condition known as traumatic brain injury (TBI).

23 Jul 2022

New microbiome-based predictive models to forecast human health outcomes

A new approach that uses artificial intelligence (AI) shows how to use microorganisms in the body and molecules in cells to predict human health outcomes, according to Penn State College of Medicine and University of Texas Southwestern Medical Center researchers.

19 Jul 2022

Researchers report genomic profiling from more than 110,000 tumors

Researchers analyzed data from the latest public release of the GENIE project of the American Association for Cancer Research.

19 Jul 2022

Rice lab’s microbial community profiling software effectively identifies bacterial species

Part of a gene is better than none when identifying a species of microbe. But for Rice University computer scientists, part was not nearly enough in their pursuit of a program to identify all the species in a microbiome.

30 Jun 2022

Scientists identify new genetic disease that delays children's intellectual development

Scientists have identified a new genetic disease, which causes some children's brains to develop abnormally, resulting in delayed intellectual development.

24 Jun 2022

Understanding how diet and the microbiome impact colorectal cancer rates

While recommended screenings beginning at age 45 have helped decrease colorectal cancer cases in older adults, cancer rates are continuing to increase in younger populations.

14 Jun 2022

Infants in industrialized nations have fewer gut bacteria that efficiently digest breast milk

The guts of infants are nearly sterile at birth, but they become a community of trillions of microbial cells, known as the microbiome, by the time they reach adulthood.

13 Jun 2022

Genomic analysis provides a deeper understanding of DCIS biology

A new study led by the global Cancer Grand Challenges PRECISION team, including researchers from The University of Texas MD Anderson Cancer Center, shifts the long-held belief that all invasive breast cancers following ductal carcinoma in situ (DCIS) arise from the original DCIS lesion.

9 Jun 2022

Infiltrating gliomas are shaped by genetic evolution and microenvironment, finds study

Researchers have discovered that infiltrating gliomas, a common brain and spinal cord tumor, are shaped by their genetic evolution and microenvironment, a finding that could lead to more targeted treatments.

9 Jun 2022

Study offers recommendations for improving statistical inference in population genomics

The second century Alexandrian astronomer and mathematician Claudius Ptolemy had a grand ambition. Hoping to make sense of the motion of stars and the paths of planets, he published a magisterial treatise on the subject, known as the Almagest.

6 Jun 2022

Combinations of multiple genetic factors play a role in the broad spectrum of autism

Autism Spectrum Disorder (ASD) is referred to as a "spectrum" because clinical features of ASD range from mild social impairments in some people to severe intellectual disability or epilepsy in others.

3 Jun 2022

New study uncovers the impact of genetic mutations on lifelong blood cell production

New research has uncovered how genetic mutations hijack the production of blood cells in different periods of life.

1 Jun 2022

Novel genetic test enables earlier, more accurate diagnosis of primary immunodeficiency disorders

Primary immunodeficiency disorders (PID) can result in chronic and sometimes life-threatening infections. More than 450 PIDs have been described, but timely and accurate diagnoses remain a challenge.

23 May 2022

Researchers show the feasibility of a comprehensive sequencing approach in pediatric and young adult cancers

New findings from researchers at Memorial Sloan Kettering Cancer Center (MSK) and published today in the journal Nature Communications report the results of using a comprehensive sequencing approach on 114 pediatric, adolescent, and young adult patients with solid tumors.

18 May 2022

Better understanding of hybrid parasite strains could improve Chagas disease diagnosis

Researchers at Karolinska Institutet in Sweden have mapped how the parasite Trypanosoma cruzi forms new variants that are more effective at evading the immune system and causing disease.

10 May 2022

UCI researchers reveal new details about a key enzyme that makes DNA sequencing possible

In a paper published today in Sciences Advances, researchers in the Department of Chemistry and the Department of Physics & Astronomy at the University of California, Irvine revealed new details about a key enzyme that makes DNA sequencing possible.

12 Mar 2022

Could oropharyngeal microflora predict COVID-19 patients' need for respiratory support?

Researchers identify oropharyngeal bacteria and metabolic pathways that are predictive of the need for respiratory support in COVID-19 patients.

7 Mar 2022

New DNA test can quickly and accurately identify a range of hard-to-diagnose genetic diseases

A new DNA test, developed by researchers at the Garvan Institute of Medical Research in Sydney and collaborators from Australia, UK and Israel, has been shown to identify a range of hard-to-diagnose neurological and neuromuscular genetic diseases quicker and more-accurately than existing tests.

4 Mar 2022

mRNA vaccines found to generate neutralizing antibodies against SARS-CoV-2 Omicron variant

A new study assessed the immunogenicity of messenger-ribonucleic acid vaccines to generate cross-reactive neutralizing antibodies against the SARS-CoV-2 Omicron variant in convalescent COVID-19 patients.

1 Mar 2022

Exploring Oxford nanopore technology-based on-site SARS-CoV-2 genome sequencing

In a new study, researchers performed genomic sequencing of SARS-CoV-2-infected samples and aimed to identify the dominant variant, assess the mutation profile, and determine the sample-to-sequence turnover time.