DNA Sequencing News and Research

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Scientists increase potency of HIV-1 antibody, identify new ways to develop vaccines

Much like coronavirus, circulating HIV-1 viruses mutate into diverse variants that pose challenges for scientists developing vaccines to protect people from HIV/AIDS.

12 Mar 2021

Rare Disease Day: Illumina shines a spotlight on people living with rare diseases

With a mission of empowering the rare disease community, Illumina has today partnered with medical researchers and families to highlight the importance of genomic sequencing and to shine the spotlight on the 300 million people worldwide living with a rare disease.

8 Mar 2021

Multidrug-resistant S. aureus strains may be spreading between pigs, farmworkers in North Carolina

DNA sequencing of bacteria found in pigs and humans in rural eastern North Carolina, an area with concentrated industrial-scale pig-farming, suggests that multidrug-resistant Staphylococcus aureus strains are spreading between pigs, farmworkers, their families and community residents, and represents an emerging public health threat, according to a study led by researchers at the Johns Hopkins Bloomberg School of Public Health.

5 Mar 2021

Identification of neutralizing IFNL3 autoantibodies in severe COVID-19 cases

Scientists have recently developed a novel alternative molecular display technology called Molecular Indexing of Proteins by Self Assembly (MIPSA). Their research explains how this technology overcomes the critical disadvantages of PLATO and other full-length protein array technologies.

5 Mar 2021

New, more reliable testing program rolled-out to hospital staff to curb Covid transmission rates

Frontline staff at Norfolk and Norwich University Hospitals are among the first in the country to benefit from the rollout of more accurate saliva tests in a bid to curb Covid transmission rates.

25 Feb 2021

World's largest resource of genome variation data on malaria parasites released

Genome variation data on more than 7,000 malaria parasites from 28 endemic countries is released today (24 February) in Wellcome Open Research.

24 Feb 2021

Plant breeding can help increase crop productivity, reduce human malnutrition

Your morning cereal or oatmeal. The bread on your sandwich. The corn chips for your snack, and the cookies for dessert. Not one would be possible with the humblest of ingredients: the seed.

17 Feb 2021

Lewy body dementia may share similar genetic profiles with Alzheimer's disease

In a study led by National Institutes of Health (NIH) researchers, scientists found that five genes may play a critical role in determining whether a person will suffer from Lewy body dementia, a devastating disorder that riddles the brain with clumps of abnormal protein deposits called Lewy bodies.

17 Feb 2021

Simple blood test can detect a wide range of diseases

In diagnostic medicine, biopsies, where a sample of tissue is extracted for analysis, is a common tool for the detection of many conditions. But this approach has several drawbacks - it can be painful, doesn't always extract the diseased tissue, and can only be used in a sufficiently advanced disease stage, making it, in some cases, too late for intervention.

9 Feb 2021

Ancestral components of human gut microbiota are fundamental to health

Neanderthals' gut microbiota already included some beneficial micro-organisms that are also found in our own intestine.

5 Feb 2021

Genetic changes linked to neurodevelopmental disabilities, cerebral palsy

Researchers have discovered a strong link between genetic changes known to cause neurodevelopmental disabilities and cerebral palsy.

2 Feb 2021

Study uncovers rare genetic syndrome caused by mutations in gene SATB1

Advances in DNA sequencing have uncovered a rare syndrome which is caused by variations in the gene SATB1.

28 Jan 2021

Innovative breakthrough promises to diagnose DNA rearrangement mutations

Doctors are increasingly using genetic signatures to diagnose diseases and determine the best course of care, but using DNA sequencing and other techniques to detect genomic rearrangements remains costly or limited in capabilities.

28 Jan 2021

A single genetic test can identify the presence and cause of mismatch repair deficiency

Researchers have developed a new integrated genetic/epigenetic DNA-sequencing protocol known as MultiMMR that can identify the presence and cause of mismatch repair (MMR) deficiency in a single test from a small sample of DNA in colon, endometrial, and other cancers.

21 Jan 2021

Researchers identify a simple way to eliminate sequencing errors produced by portable DNA sequencer

Researchers have found a simple way to eliminate almost all sequencing errors produced by a widely used portable DNA sequencer, potentially enabling scientists working outside the lab to study and track microorganisms like the SARS-CoV-2 virus more efficiently.

13 Jan 2021

Researchers develop improved process for large-scale electron microscopy to visualize small structures

How are networks of neurons connected to make functional circuits? This has been a long-standing question in neuroscience. To answer this fundamental question, researchers from Boston Children's Hospital and Harvard Medical School developed a new way to study these circuits and in the process learn more about the connections between them.

12 Jan 2021

Researchers trace back the evolutionary history of antibiotic resistance genes

By comparing thousands of bacterial genomes, scientists in Gothenburg, Sweden have traced back the evolutionary history of antibiotic resistance genes.

7 Jan 2021

New selective method for DNA sequencing could enable quicker diagnosis of rare diseases

Scientists at the University of Nottingham have made a major breakthrough in genome sequencing, which will enable them to search for the underlying causes of diseases in human DNA quicker than ever before.

30 Nov 2020

Somatic mutation may act as a natural gene therapy in patients with rare autosomal disease

Researchers affiliated with the Center for Cell-Based Therapy in Ribeirão Preto, Brazil, have identified for the first time a non-hereditary mutation in blood cells from a patient with GATA2 deficiency, a rare autosomal disease caused by inherited mutations in the gene that encodes GATA-binding protein 2 (GATA2).

17 Nov 2020

Single clinical laboratory test can rapidly detect serious infections

UC San Francisco scientists have developed a single clinical laboratory test capable of zeroing in on the microbial miscreant afflicting patients hospitalized with serious infections in as little as six hour.

11 Nov 2020