Dehydroepiandrosterone News and Research

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Dehydroepiandrosterone is a substance being studied in the prevention of cancer. It is a type of steroid. Also called DHEA.

Biological mechanisms contribute to stress resilience

It is important to understand what biological mechanisms contribute to an individual’s capacity to be resilient under conditions of extreme stress, such as those regularly experienced by soldiers, police, and firefighters.

5 Aug 2009

Dietary supplements with steroids pose health risks

Three cases of patients suffering from the adverse affects of steroid-enriched dietary supplements have been reported by researchers at Henry Ford Hospital.

4 Aug 2009

DHEA supplement combined with vitamin D and calcium significantly improves spinal bone density in older women

"The results of our study are very promising. Similar studies have demonstrated much smaller benefits for bone than we found. However, calcium and vitamin D deficiencies, which are present in half of older adults, may have prevented DHEA from improving bone density in the earlier studies," said Edward Weiss, Ph.D., associate professor of nutrition and dietetics at Saint Louis University's Doisy College of Health Sciences and lead author of the study.

12 May 2009

Samaritan Pharmaceuticals granted IND from FDA for HIV drug

Samaritan Pharmaceuticals has announced that it has filed an IND (Investigational New Drug) application for SP-6310 in the treatment of HIV-infected patients with abnormal cortisol levels.

8 Jul 2008

Women with hgher levels of DHEAS have better cognitive function

Women with naturally higher levels of the hormone precursor DHEAS were found to have better cognitive function than women with lower levels, according to a new study appearing in the March issue of the Journal of Clinical Endocrinology & Metabolism (JCEM).

22 Feb 2008

Nationwide survey reports a high rate of concern about body image in both boys and girls

A nationwide survey of more than 10,000 adolescents, published in the August issue of Pediatrics, reports a high rate of concern about body image in both boys and girls, and finds that adolescents with such concerns are much more likely to use hormones and dietary supplements to enhance their physique.

1 Aug 2005

Sex hormone levels not linked to low sexual desire

No single androgen (sex hormone) level was found to be predictive of low sexual function in women, according to a study in the July 6 issue of JAMA.

6 Jul 2005

Study links TNF to androgen deficiency in rheumatoid arthritis patients and suggest a novel pathway in inflammation

A protein involved in multiple cell functions, tumor necrosis factor (TNF) is perhaps best known for provoking destructive inflammation. Recently, drugs blocking the action of TNF have shown promise in the early treatment of rheumatoid arthritis (RA).

2 Jun 2005

Over-the-counter DHEA hormonal therapy may be an effective treatment for depression

The over-the-counter hormonal therapy known as DHEA may be an effective treatment of midlife-onset minor and major depression, according to a study in the February issue of The Archives of General Psychiatry. DHEA (dehydroepiandrosterone), an adrenal androgen and neurosteroid is available as a supplement in the U.S.

7 Feb 2005

Sex hormones modulate brain damage in multiple sclerosis

Abnormalities in sex hormone levels may contribute to the damage to brain tissue typical of multiple sclerosis, indicates research in the Journal of Neurology Neurosurgery and Psychiatry.

16 Jan 2005

Dietary supplement DHEA could play a role in reducing abdominal fat in elderly men and women

Preliminary research indicates that the dietary supplement DHEA could play a role in reducing abdominal fat in elderly men and women with age-related decreases in DHEA levels, according to a study in the November 10 issue of JAMA.

10 Nov 2004

Higher levels of certain hormones may be associated with stress

Higher levels of certain hormones may be associated with stress, and can influence a person's ability to cope with the negative effects of stress, according to an article in the August issue of the Archives of General Psychiatry, one of the JAMA/Archives journals.

2 Aug 2004

Estrogen therapy may help bone density, muscle mass, sexual function, memory, and psychological wellbeing in postmenopausal women

Research in monkeys suggests that long-term use of estrogen therapy may reduce levels of androgens – hormones involved in maintaining bone density, muscle mass, sexual function, memory, and psychological wellbeing in postmenopausal women.

14 May 2004

Risk of prostate cancer greater in men over 50 with high levels of testosterone

Men over 50 years of age with high blood levels of testosterone have an increased risk of prostate cancer, according to a study by researchers at Johns Hopkins and the National Institute on Aging. The finding throws some doubt on the safety of testosterone replacement therapy, the investigators say.

11 May 2004

Dietary supplement may improve immune function in the elderly

A recent clinical study has demonstrated that 7-oxo Dehydroepiandrosterone taken orally twice daily by healthy adults over a period of one month augments several key T-cell mediated immune function parameters compared to placebo administration.

20 Apr 2004