Demyelination News and Research

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A demyelinating disease is any disease of the nervous system in which the myelin sheath of neurons is damaged. This impairs the conduction of signals in the affected nerves, causing impairment in sensation, movement, cognition, or other functions depending on which nerves are involved.

Treatment for neurological diseases often no longer effective enough in the later stages

Neurological diseases often begin with an inflammatory process and the degradation of the so-called myelin layer, which surrounds the nerve fibers (axons) like a protective insulating layer.

28 Sep 2022

Neurological manifestations associated with monkeypox infection

A new study presents current information regarding the neurological presentations and complications of monkeypox infection.

5 Sep 2022

The currently available evidence on viral-induced parkinsonism

A new review attempts to summarize all known about the relationship between viral illness and parkinsonian disorders to facilitate further research.

31 Aug 2022

Study confirms link between Epstein-Barr virus and multiple sclerosis

Researchers investigate the association between Epstein-Barr virus infection and multiple sclerosis.

26 Jul 2022

Oral administration of rapamycin increases β-amyloid buildup in Alzheimer's disease mouse model

Researchers from The University of Texas Health Science Center at San Antonio (UT Health San Antonio) have found that oral administration of rapamycin to an Alzheimer's disease mouse model causes an increase in beta (β)-amyloid protein plaques. β-amyloid buildup is a hallmark of Alzheimer's disease.

7 Jun 2022

Using diffusion-weighted MRI to visualize brain inflammation in vivo for the first time

Research of the laboratories led by Dr. Silvia de Santis and Dr. Santiago Canals, both from the Institute of Neurosciences UMH-CSIC (Alicante, Spain), has made it possible to visualize for the first time and in great detail brain inflammation using diffusion-weighted Magnetic Resonance Imaging.

27 May 2022

Administration of a lipid reduces inflammation associated with multiple sclerosis in mice

A team led by the Institut de Neurociències at the Universitat Autònoma de Barcelona managed to reduce chronic inflammation associated with multiple sclerosis in mice thanks to the administration of a type of lipid that mediates inflammation.

27 Apr 2022

Cow's milk protein can trigger inflammation in multiple sclerosis sufferers

Multiple sclerosis sufferers often complain of more severe disease symptoms after consuming dairy products. Researchers at the Universities of Bonn and Erlangen-Nuremberg have now found a possible cause for this.

1 Mar 2022

Researchers demonstrate the powerful gene silencing effects of HDO technology

T and B lymphocytes, which are part of a group of immune cells commonly called white blood cells, work together to eliminate foreign invaders in the body such as viruses.

28 Feb 2022

Researchers discover how pre-transplant chemotherapy facilitates the replacement of microglial cells

More than 50,000 bone marrow-derived stem cell transplants are performed worldwide each year to treat a wide range of conditions, including brain diseases.

21 Feb 2022

The long-term neurologic consequences of COVID-19

A team of researchers recently provided insights into central nervous system consequences of the coronavirus disease 2019 (COVID-19) in a perspective paper published in the Science journal.

24 Jan 2022

Scientists show how cold could alleviate multiple sclerosis symptoms

In evolutionary biology, the "Life History Theory", first proposed in the 1950s, postulates that when the environment is favorable, the resources used by any organism are devoted for growth and reproduction.

25 Oct 2021

SARS-CoV-2 infection may prompt Guillain-Barré syndrome

A new paper in Brain, published by Oxford University Press, indicates that a COVID-19 infection may prompt Guillain-Barré syndrome.

23 Sep 2021

Restoring cholesterol levels could be a new therapeutic approach for diseases linked to TDP-43 protein

Researchers in Singapore have discovered that brain cells cannot maintain the cholesterol-rich myelin sheath that protects and insulates neurons in the absence of a protein called TDP-43.

4 Aug 2021

World Brain Day 2021: An interview with Professor Alan Thompson

In commemoration of World Brain Day 2021, News-Medical spoke to renowned neurology expert Professor Alan Thompson about his incredible career in brain research.

21 Jul 2021

New research may offer clues to why MS patients develop progressive disability

Did you know multiple sclerosis (MS) means multiple scars? New research shows that the brain and spinal cord scars in people with MS may offer clues to why they developprogressive disability but those with related diseases where the immune system attacks the central nervous system do not.

19 Jul 2021

Researchers discover two new types of glial cells in the brain

Neurons, nerve cells in the brain, are central players in brain function. However, a key role for glia, long considered support cells, is emerging.

14 Jun 2021

Study identifies how SARS-CoV-2 enters and infects the brain

A recent preclinical study led by Anja Kipar of the University of Zurich and the University of Liverpool found evidence of the virus infecting and eventually provoking cell death in microglia and immune cells — but not neurons. The viral-induced apoptosis in these brain cells may explain why some long-haulers experience ‘brain fog’ months after recovery.

21 Apr 2021

Researchers develop a classification scheme for neuromyelitis optica spectrum disorder

Researchers in the Department of Neurology at Tohoku University, which is led by professor Masashi Aoki, have developed a classification scheme for neuromyelitis optica spectrum disorder, a rare autoimmune disease that until recently was thought to be a type of multiple sclerosis (MS).

15 Apr 2021

Study identifies key gene associated with age-related brain deterioration

A new study led by the University of Portsmouth has identified that one of the major factors of age-related brain deterioration is the loss of a substance called myelin.

10 Mar 2021