Dendrimer News and Research

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Nanocomposite labeled cancer cells can be targeted and destroyed using lasers

A nanocomposite particle can be constructed so that it has a mix of properties that would not otherwise happen in nature.

22 May 2007

Nanoparticles rely on 'velcro effect' to target tumor cells

One of the basic tenets of targeted nanoparticle drug delivery is putting multiple targeting molecules on a nanoparticle surface will improve the ability of nanoparticles to stick to their targeted cell and deliver their drug cargos to the appropriate diseased cell.

20 Feb 2007

Second-generation dendrimer disintegrates upon command

Dendrimers, highly branched, spherical polymers, have demonstrated their utility as drug and imaging agent delivery vehicles for use in detecting and treating cancer, with several dendrimer-based agents nearing human clinical trials.

29 Jan 2007

Dendrimer-based targeted delivery of an apoptotic sensor in cancer cells

Taking a critical step toward the development of a multifunctional nanoscale anticancer agent that can detect cancer, treat it, and then report on the success or failure of that treatment, investigators at the University of Michigan have developed a nanoscale sensor of cell death.

22 Jan 2007

Dendrimer-encapsulated camptothecins

With an eye toward developing a delivery vehicle for anticancer agents that are poorly soluble in water, a research team at Boston University and the Research Triangle Institute (RTI) has developed a biocompatible dendrimer that wraps itself around water-insoluble drugs.

8 Jan 2007

Nanotechnology continues to advance anticancer gene therapy

Given that cancer is a disease in which genetic errors play a major role, it should come as no surprise that many experts envision a time when gene therapy will play an equally important role in the treatment of cancer.

20 Nov 2006

A single dose of doxorubicin-functionalized bow-tie dendrimer cures mice bearing C-26 colon carcinomas

In a dramatic demonstration of the power of nanotechnology, a team of investigators has designed a nanoscale, polymeric drug delivery vehicle that when loaded with a widely used anticancer agent cures colon cancer in mice with a single dose.

13 Nov 2006

Nanotechnology used to smuggle a powerful chemotherapeutic drug inside tumor cells

University of Michigan scientists have created the nanotechnology equivalent of a Trojan horse to smuggle a powerful chemotherapeutic drug inside tumor cells - increasing the drug's cancer-killing activity and reducing its toxic side effects.

15 Jun 2005

Starpharma launches new start-up biotechnology company

Starpharma Holdings Limited today announced the establishment of a start-up biotechnology company (as a foundation shareholder).

15 Mar 2005

Astronaut's eyes may become windows on the bloodstream

Our eyes may become more than windows of the soul if a multidisciplinary team of University of Michigan researchers succeeds with a clever combination of nanoparticles and ultrafast pulsed laser to see individual cells as they zip past in the bloodstream.

29 Nov 2004

Australian nanotech Starpharma to develop a second generation microbicide for the prevention of infection by HIV

Melbourne-based nanotechnology company Starpharma will lead a consortium to develop a second generation microbicide for the prevention of infection by HIV and other sexually transmitted diseases (STDs).

30 Sep 2004

Carbohydrate-binding proteins are becoming extremely useful in curing various illnesses

Researchers are beginning to see the potential for breakthrough in healthcare through glycomics, which studies carbohydrates, proteins and their interactions. In fact, these carbohydrates are moving beyond their regular roles as sugar storage bins.

28 Apr 2004