Dendritic Cell

Dendritic Cells are a special type of immune cell that is found in tissues, such as the skin, and boosts immune responses by showing antigens on its surface to other cells of the immune system. A dendritic cell is a type of phagocyte and a type of antigen-presenting cell (APC).

What are Dendritic Cells?

Dendritic cells are a type of antigen-presenting cell (APC) that form an important role in the adaptive immune system.

Types of Dendritic Cells

Dendritic Cell Life Cycle

Dendritic Cells and Cytokines

Dendritic Cells and HIV

Latest Dendritic Cell News and Research

New trials show promise for immune checkpoint blockers in early-stage lung cancer

A dendritic cell (DC) vaccine targeting patient-specific neoantigens to patients with resected non-small cell lung cancer (NSCLC).

18 Apr 2024

CPRIT awards MD Anderson 16 grants to support cancer research and prevention

The University of Texas MD Anderson Cancer Center today was awarded 16 grants totaling over $25.5 million from the Cancer Prevention and Research Institute of Texas (CPRIT) in support of cancer screening, early detection and prevention programs, faculty recruitment, and groundbreaking cancer research across all areas of the institution.

21 Feb 2024

How immune cells shape our earliest breaths

Study profiles the development of immune cells in human lungs during embryonic and fetal stages, revealing their influence on epithelial cell fate and lung development.

1 Jan 2024

New optimized vaccine approach targets Hepatitis C virus variability

A method to design vaccines for highly variable viruses like the hepatitis C virus.

12 Dec 2023

Revolutionary advances in psoriasis treatment: unveiling new therapeutic approaches

Psoriasis etiopathogenesis and treatment.

29 Nov 2023

Short-chain fatty acids produced by intestinal bacteria play role in dendritic cell elongation

Dendritic cells play a key role in the mammalian immune system. These cells are present throughout the human body and are known to capture foreign bodies, i.e., antigens, using extendable "arms" called dendrites.

30 Oct 2023

Pitt scientists develop new approach to reduce side effects of organ transplants

Giving living donor liver transplant recipients an infusion of immune cells derived from their donor a week before transplantation is feasible, safe – and may lead to recipients being successfully weaned off immunosuppressant medications without rejecting the transplanted organ.

11 Oct 2023

Radiation therapy combined with two types of immunotherapy could be effective against cold tumors

Researchers at Weill Cornell Medicine have discovered that radiation therapy combined with two types of immunotherapy-;one that boosts T cells, and another that boosts dendritic cells-;can control tumors in preclinical models of triple negative breast cancer, a cancer type that's typically resistant to immunotherapy alone.

25 Sep 2023

ACT and personalized cancer vaccine combo shows efficacy in ovarian cancer patients

A Ludwig Cancer Research study has shown that combining adoptive T cell therapy (ACT) with an innovative, personalized cancer vaccine under development at the Lausanne Branch of the Ludwig Institute for Cancer Research can benefit patients with late-stage, drug-resistant ovarian cancer.

21 Sep 2023

Unlocking the secret soldiers: How dendritic cells could revolutionize cancer immunotherapy

A recent review in the journal Immunity delves into the crucial role of dendritic cells (DCs) in shaping T-cell responses in cancer, highlighting their importance in both priming anti-tumor immunity and in ongoing immune interactions within tumors. The findings underscore the potential of DCs as key targets for next-generation cancer immunotherapies.

18 Sep 2023

Dectin-1 stimulation promotes pro-inflammatory response in HIV-positive individuals

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 16, entitled, "Dectin-1 stimulation promotes a distinct inflammatory signature in the setting of HIV-infection and aging."

31 Aug 2023

Glycans and GBPs: How their interplay shapes immunity in infection and autoimmune diseases

Researchers discuss the regulatory roles of glycans and glycan-binding proteins in modulating immune responses.

21 Aug 2023

Dendritic cells found to kill CD47-deficient T cells

Researchers at Kobe University discovered an entirely new and unexpected mechanism by which the immune system can get rid of cells lacking molecules that identify them as part of the self in mice.

8 Aug 2023

Neoantigen discovery sheds light on cancer immunogenicity

Researchers reported a proteogenomic approach to investigate fresh solid melanoma tumor material.

4 Aug 2023

New insights into dendritic cell biology could lead to improved cancer therapies

The cells of the immune system circulate mainly in the blood and migrate into the body's tissues after an inflammation. Some types of immune cells, however, are permanently located in the tissues, where they come together to form three-dimensional networks.

17 Jul 2023

Study shows how glutamine can help or hinder cancer-killing activity

Scientists at St. Jude Children's Research Hospital found immune and tumor cells compete over glutamine, a major nutrient in their local environment, with significant implications for anti-cancer activity.

5 Jul 2023

How does space affect the immune system of astronauts?

Research explores the effects of microgravity and radiation on the immune system in space conditions. It emphasizes the need to understand these effects for future long-duration space missions and highlights knowledge gaps for further investigation.

2 Jul 2023

New nanoparticle could improve the delivery of mRNA-based vaccines

Johns Hopkins Medicine scientists say they have developed a nanoparticle -; an extremely tiny biodegradable container -; that has the potential to improve the delivery of messenger ribonucleic acid (mRNA)-based vaccines for infectious diseases such as COVID-19, and vaccines for treating non-infectious diseases including cancer.

28 Jun 2023

2023 PCRF grant recipients announced for exploring new, safer treatments for pediatric cancers

The Pediatric Cancer Research Foundation, a nonproﬁt focused on transforming pediatric cancer care by accelerating research breakthroughs, today announced the 19 recipients of its 2023 research grants.

26 May 2023

Study pinpoints how gut microbes boost the body's response to cancer immunotherapy

Cancer immunotherapy has transformed the treatment of many types of cancer. Yet, for reasons that remain poorly understood, not all patients get the same benefit from these powerful therapies.

4 May 2023

Dendritic Cell

Overview

Types of Dendritic Cells

Dendritic Cell Life Cycle

Dendritic Cells and Cytokines

Feature Articles

Dendritic Cells and HIV

Latest Dendritic Cell News and Research

New trials show promise for immune checkpoint blockers in early-stage lung cancer

CPRIT awards MD Anderson 16 grants to support cancer research and prevention

How immune cells shape our earliest breaths

New optimized vaccine approach targets Hepatitis C virus variability

Revolutionary advances in psoriasis treatment: unveiling new therapeutic approaches

Short-chain fatty acids produced by intestinal bacteria play role in dendritic cell elongation

Pitt scientists develop new approach to reduce side effects of organ transplants

Radiation therapy combined with two types of immunotherapy could be effective against cold tumors

ACT and personalized cancer vaccine combo shows efficacy in ovarian cancer patients

Unlocking the secret soldiers: How dendritic cells could revolutionize cancer immunotherapy

Dectin-1 stimulation promotes pro-inflammatory response in HIV-positive individuals

Glycans and GBPs: How their interplay shapes immunity in infection and autoimmune diseases

Dendritic cells found to kill CD47-deficient T cells

Neoantigen discovery sheds light on cancer immunogenicity

New insights into dendritic cell biology could lead to improved cancer therapies

Study shows how glutamine can help or hinder cancer-killing activity

How does space affect the immune system of astronauts?

New nanoparticle could improve the delivery of mRNA-based vaccines

2023 PCRF grant recipients announced for exploring new, safer treatments for pediatric cancers

Study pinpoints how gut microbes boost the body's response to cancer immunotherapy

Immunology eBook

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

Dendritic Cell

Overview

Feature Articles

Dendritic Cells and HIV

Latest Dendritic Cell News and Research

Immunology eBook

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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