Depressive Disorder News and Research

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Study explores the potential of robotic-assisted TMS for depression

In a recent study published in the Scientific Reports, a group of researchers evaluated the efficiency, therapeutic efficacy, and patient perceptions of a custom robotic system for transcranial magnetic stimulation (TMS) coil placement in treating depression compared to traditional manual methods.

31 Aug 2023

Spending on mental health services rose by 53% during the COVID-19 pandemic

Spending on mental health services among Americans with private health insurance has surged since the beginning of the COVID-19 pandemic, continuing to rise even as the use of telehealth has plateaued, according to a new study.

25 Aug 2023

Depression survivors spend more time processing negative information

People who have recovered from a major depressive episode, when compared with individuals who have never experienced one, tend to spend more time processing negative information and less time processing positive information, putting them at risk for a relapse, according to research published by the American Psychological Association.

21 Aug 2023

ADHD diagnosis in childhood vs adulthood: is there a difference in genetic architecture?

Researchers investigated whether individuals diagnosed with ADHD during childhood vs adulthood differed in terms of unique and shared genetic and functional architectures.

9 Aug 2023

Is a Western diet a risk factor for major depressive disorder?

Researchers investigated whether the Western diet (WD) was a risk element for major depressive disorder (MDD) patients.

8 Aug 2023

Similarities in gene expression between post-mortem and living human brains

Researchers compare human prefrontal cortex gene expression between living and post-mortem samples.

7 Aug 2023

GABA-modulating treatments could help tackle cognitive, affective symptoms associated with depression

Depression is a complex condition correlated with multiple differences in brain function and mechanisms. A new paper spanning known data about the neurotransmitter GABA and its principal receptors showcases evidence of the receptors' importance in depression and potential as therapeutic targets.

3 Aug 2023

Uncommon genetic allele variants may play a vital role in treatment-resistant depression, finds study

The association between treatment-resistant depression and uncommon functional genetic alleles.

3 Aug 2023

Sex differences in depression: Including transgender and intersex populations in mental health research

In 2016, recognizing that lack of research in female animals was hampering the success of treatments for mood disorders, the National Institutes of Health (NIH) changed its policy for basic research to include sex as a biological variable for basic research, a move that triggered an explosion of research into sex differences.

1 Aug 2023

Research reveals surprising genetic overlap between neurological and psychiatric disorders

Researchers compared the shared genetic risk and biological foundations of neurological and mental illnesses.

1 Aug 2023

Trial evaluates purine P2X7 receptor antagonist JNJ-54175446 in patients with major depressive disorder

Researchers investigated the safety and pharmacokinetics of JNJ-54175446 in a double-blind, multicenter, randomized controlled trial (RCT).

31 Jul 2023

MUSC study to determine optimal dose of transcranial magnetic stimulation for MCI

With more than $3.7 million in funding from the National Institute on Aging, Medical University of South Carolina neuropsychologist Andreana Benitez, Ph.D., of the Department of Neurology in the College of Medicine will lead a phase II clinical trial to determine the optimal dose of transcranial magnetic stimulation, or TMS, needed to improve symptoms for patients with depression and mild cognitive impairment, or MCI.

28 Jul 2023

Amotivation and anhedonia play a crucial role in determining the social functioning of schizophrenia patients

Dr. Raymond Chan's team from the Institute of Psychology of the Chinese Academy of Sciences and his collaborators have recently shown that amotivation and anhedonia, rather than expressive dysfunction, play a crucial role in determining the social functioning of schizophrenia patients.

27 Jul 2023

Insights into the pathophysiological mechanisms governing neuropsychiatric symptoms of multiple sclerosis

Researchers pursued insights into the pathophysiological mechanisms governing neuropsychiatric symptoms of MS.

21 Jul 2023

Study finds highly specific polygenic signatures across multidimensional symptoms of bipolar disorder

Researchers analyzed the relationships between polygenic liability for bipolar disorder, schizophrenia, and major depressive disorder.

13 Jul 2023

Do the benefits of dog ownership on cardiovascular disease and diabetes extend to US military Veterans?

A study finds that dog ownership reduces the risk of cardiometabolic disease among US military veterans.

12 Jul 2023

Abnormal cortical folding linked to major depressive disorder

Major depressive disorder (MDD) is a complex and debilitating metal illness. Given its complex and widespread nature, MDD has been a subject of intense medical research.

10 Jul 2023

Depression after TBI may not be the same as depression related to other causes, study suggests

A new study led by Shan Siddiqi, MD, from Brigham and Women’s Hospital, a founding member of the Mass General Brigham healthcare system, suggests that depression after traumatic brain injury (TBI) could be a clinically distinct disorder rather than traditional major depressive disorder, with implications for patient treatment.

10 Jul 2023

TBI-associated depression may be a distinct disorder

A new study led by Shan Siddiqi, MD, from Brigham and Women's Hospital, a founding member of the Mass General Brigham healthcare system, suggests that depression after traumatic brain injury (TBI) could be a clinically distinct disorder rather than traditional major depressive disorder, with implications for patient treatment.

5 Jul 2023

New biomarker for major depressive disorder identified

In appearance, the human brain's outermost layer, called the cortex, is a maze of tissue folds. The peaks or raised surfaces of these folds, called gyri, play an important role in the proper functioning of the brain.

4 Jul 2023