Developmental Disorder News and Research

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Psychotropic medications common among children with ASD: Research

Behavioral interventions typically are the first line of treatment to manage unwanted behaviors in children with autism spectrum disorders. If behaviors do not improve, medications frequently are added to the mix.

3 May 2010

ATN study shows prevalence of GI symptoms in children with ASD

Parents of children and adolescents with autism spectrum disorders sometimes report that their children suffer from gastrointestinal symptoms, such as diarrhea and constipation. However, studies on how prevalent these symptoms are have had conflicting results.

3 May 2010

Children with developmental regression at increased risk for more severe autism: Study

Kennedy Krieger Institute announced today new study results showing that when and how autism symptoms appear in the first three years of life has vital implications to a child's developmental, diagnostic, and educational outcomes.

21 Apr 2010

Study: Chromosomal microarray analysis detects genetic changes related to ASDs better than standard tests

A large study from Children's Hospital Boston and the Boston-based Autism Consortium finds that a genetic test that samples the entire genome, known as chromosomal microarray analysis, has about three times the detection rate for genetic changes related to autism spectrum disorders (ASDs) than standard tests. Publishing in the April issue of Pediatrics (and online March 15), the authors urge that CMA become part of the first-line genetic work-up for ASDs.

15 Mar 2010

Genetic test for autism: Transgenomic licenses exclusive intellectual property from IntegraGen

Transgenomic, Inc. announced today that it has licensed on an exclusive U.S. basis intellectual property from IntegraGen SA that will enable Transgenomic to develop and commercialize a genetic test designed to assess the risk of autism in children who have older siblings diagnosed with an autism spectrum disorder. Under the agreement Transgenomic will develop the test in the Company's CAP-accredited and CLIA-certified laboratory, and anticipates launching the new test in the second quarter of 2010. Financial terms of the agreement were not disclosed.

24 Feb 2010

Nascent symptoms of autism in infants emerge during latter part of first year of life

A study of the development of autism in infants, comparing the behavior of the siblings of children diagnosed with autism to that of babies developing normally, has found that the nascent symptoms of the condition - a lack of shared eye contact, smiling and communicative babbling - are not present at 6 months, but emerge gradually and only become apparent during the latter part of the first year of life.

16 Feb 2010

Learning Lab of Brentwood to present free seminar on ADHD in Brentwood

The Learning Lab of Brentwood will present a free seminar, ADHD Kids: Getting Along Socially, on Thursday February 18 from 12:00-1:30 PM at the Maryland Farms YMCA in Brentwood.

12 Feb 2010

Autism Speaks: Ten most significant autism research achievements in 2009

Autism Speaks, the world's largest autism science and advocacy organization has released its annual list of the 10 most significant research achievements to have impacted autism during the previous year. Every year, Autism Speaks documents the progress made toward its mission to discover the causes and treatment for autism spectrum disorders, and compiles a list of the 10 most significant research achievements to have impacted autism during the previous year.

10 Feb 2010

APA releases proposed draft diagnostic criteria for DSM-5

The American Psychiatric Association today released the proposed draft diagnostic criteria for the fifth edition of Diagnostic and Statistical Manual of Mental Disorders (DSM). The draft criteria represent content changes under consideration for DSM, which is the standard classification of mental disorders used by mental health and other health professionals, and is used for diagnostic and research purposes.

10 Feb 2010

Advanced paternal age increases autism risk only when the mother is younger

Advanced maternal age is linked to a significantly elevated risk of having a child with autism, regardless of the father's age, according to an exhaustive study of all births in California during the 1990s by UC Davis Health System researchers. Advanced paternal age is associated with elevated autism risk only when the father is older and the mother is under 30, the study found.

9 Feb 2010

Research suggests growth factor gene plays a central role in palate development

Cleft palate has been linked to dozens of genes. During their investigation of one of these genes, researchers at Washington University School of Medicine in St. Louis were surprised to find that cleft palate occurs both when the gene is more active and when it is less active than normal.

3 Feb 2010

GMC's findings against Dr. Wakefield unjust and a threat to researchers investigating autism

Parents of children with autism around the world are calling the findings against Dr. Andrew Wakefield in the UK's General Medical Council (GMC) unjust and a threat to researchers investigating autism as a medical condition. The verdict comes less than a month after an article in the journal Pediatrics urged further study of a link between gastrointestinal disturbances and autism originally pointed out by Dr. Wakefield in 1988.

29 Jan 2010

New Tel Aviv University study shows early intervention could prevent mind altering disorder

The onset of schizophrenia is not easy to predict. Although it is associated with as many as 14 genes in the human genome, the prior presence of schizophrenia in the family is not enough to determine whether one will succumb to the mind-altering condition. The disease also has a significant environmental link.

29 Jan 2010

Common variations in genes associated with microcephaly may explain differences in brain size

A group of Norwegian and American researchers have shown that common variations in genes associated with microcephaly - a neuro-developmental disorder in which brain size is dramatically reduced - may explain differences in brain size in healthy individuals as well as in patients with neurological and psychiatric disorders.

22 Dec 2009

Early intervention for young children with autism improves IQ, communication and social interaction

A novel early intervention program for very young children with autism - some as young as 18 months - is effective for improving IQ, language ability, and social interaction, a comprehensive new study has found.

30 Nov 2009

Children with ASD have problem with handwriting: Study

Handwriting skills are crucial for success in school, communication, and building children's self-esteem. The first study to examine handwriting quality in children with autism spectrum disorders (ASD) has uncovered a relationship between fine motor control and poor quality of handwriting in children with ASD, according to research published in the November 10, 2009, issue of Neurology-, the medical journal of the American Academy of Neurology.

10 Nov 2009

Kennedy Krieger Institute announces the results of largest ever twin study of ASDs

Kennedy Krieger Institute announced today new study results from the largest ever twin study that confirm the role genetics plays in autism spectrum disorders (ASDs), but also suggest that environmental factors play a role.

6 Oct 2009

New findings reinforce the urgency of autism as a major global public health crisis

Autism Speaks together with Autism Speaks Canada, North America's largest autism science and advocacy organization, today responded to a new study published in the American Academy of Pediatrics' journal Pediatrics that found a parent-reported autism prevalence rate of one in every 91 American children, including one in 58 boys.

6 Oct 2009

New insight into human ciliopathy

In the September 1st issue of G&D, Dr. Karen Oegema (UCSD) and colleagues identify the molecular basis of the lethal developmental disorder, hydrolethalus syndrome, and reveal that hydrolethalus syndrome actually belongs to the emerging class of human ciliopathy diseases.

4 Aug 2009

Autism discovery may explain why disorder strikes boys four times more than girls

UCLA scientists have discovered a variant of a gene called CACNA1G that may increase a child's risk of developing autism, particularly in boys. The journal Molecular Psychiatry publishes the findings in its May 19 advance online edition.

19 May 2009