Dexamethasone News and Research

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"Smart" sutures can detect inflammation and release drugs

Inspired by sutures developed thousands of years ago, MIT engineers have designed "smart" sutures that can not only hold tissue in place, but also detect inflammation and release drugs.

16 May 2023

Anticoronavirals: the development of COVID-19 therapies and the challenges that remain

Researchers highlighted the pace of development of COVID-19 therapies during the pandemic and the challenges that hinder the widespread availability of anticoronavirals.

8 May 2023

Novel immunotherapy appears to be safe, well tolerated by children with relapsed brain tumors

The first in-human-study of a new immunotherapy that blocks a natural enzyme tumors commandeer for their protection was well tolerated by children with relapsed brain tumors and enabled many to have unexpected months of a more normal life, researchers say.

25 Apr 2023

Researchers develop a backpack-based myeloid cell therapy for MS patients

Multiple sclerosis (MS) is a devastating autoimmune disease that destroys the protective myelin covering around nerves, disrupting communication between the brain and body, and causing patients' ability to move and function to progressively decline.

21 Apr 2023

Early use of dexamethasone associated with reduced mortality in hospitalized COVID-19 requiring breathing support

In a recent study published in the journal JAMA Network Open, researchers examined the clinical use of dexamethasone for hospitalized patients with coronavirus disease 2019 (COVID-19) respiratory illness and explored the heterogeneity of treatment outcomes across different subgroups.

19 Apr 2023

Case report on Nocardia pseudobrasiliensis and SARS-CoV-2 concomitant infection

In a recent case report published in the U.S. Centers for Disease Control and Prevention’s (CDC) journal Emerging Infectious Diseases, researchers reported a case of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and Nocardia pseudobrasiliensis concomitant infection.

27 Mar 2023

Candida auris infection without epidemiologic links to a prior outbreak

The Centers for Disease Control and Prevention (CDC) has classified Candida auris (C. auris) as an urgent public threat due to its role in elevating mortality, its ability to persist in hospital environments, and the high possibility of developing pan-drug resistance.

23 Mar 2023

Using nanoparticles to encapsulate the medication may make corneal grafts more successful

Corneal transplants can be the last step to returning clear vision to many patients suffering from eye disease. Each year, approximately 80,000 corneal transplantations take place in the U.S. Worldwide, more than 184,000 corneal transplantation surgeries are performed annually.

23 Mar 2023

The impact of specific comorbidities and overall multimorbidity on the three mechanistically distinct phases of COVID-19

Researchers studied the impact of comorbidities in the three distinct phases of COVID-19.

21 Feb 2023

New insights into the driving factors of COVID-19 dynamics in England

In a recent study posted to the medRxiv* preprint server, researchers provided quantitative estimates of population-level drivers of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission and infection severity by fitting coronavirus disease 2019 (COVID-19) epidemiological surveillance data from England into dynamic transmission models.

15 Feb 2023

Combined glucocorticoid steroids and statin therapy may be safer for the treatment of preterm birth

Potentially life-saving steroids commonly given to preterm babies also increase the risk of long-term cardiovascular problems, but a new study in rats has found that if given in conjunction with statins, their positive effects remain while the potential negative side-effects are 'weeded out'.

2 Feb 2023

New scan reliably detects primary aldosteronism, a common cause of hypertension

In a recent article, researchers performed a prospective within-patient clinical trial, Is Metomidate superior to AVS in predicting ouTComes from adrenalectomy in primary Hyperaldosteronism (MATCH) in the United Kingdom (UK) in primary aldosteronism (PA) patients. These patients suffered from high blood pressure caused by a steroid hormone, aldosterone.

19 Jan 2023

Scientists explore efficacy of small molecule drugs against severe COVID-19 in vitro

Researchers evaluated the efficacy of small molecule drugs against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in vitro.

29 Dec 2022

IU researchers uncover new ways to prevent serious side effects for breast cancer patients

Researchers at Indiana University School of Medicine are learning more about ways to prevent serious side effects from chemotherapy used to treat breast cancer patients.

20 Dec 2022

No benefit of low dose apixaban following acute COVID-19

The HEAL-COVID trial compared the efficacy of Apixaban to standard care in adults who have recently recovered from severe COVID-19.

14 Dec 2022

Study examines whether cortisone-like medicine can reduce pain after total knee arthroplasty

Results from a study by Henry Ford Health orthopedic researchers is the latest of several high-powered studies geared toward effectively managing pain and decreasing opioids use after total knee replacement surgery.

5 Dec 2022

Exploring clinical characteristics and outcomes of hospitalized COVID-19 patients

Researchers described the clinical characteristics and outcomes of patients hospitalized with coronavirus disease 2019 (COVID-19) in the Netherlands.

24 Nov 2022

Study aims to develop broad-spectrum antivirals against SARS-CoV-2 via drug repurposing strategies

This study aims to determine which FDA-approved compound(s) can be repurposed as a broad-spectrum antiviral drug(s) against SARS-CoV-2 and variants.

24 Nov 2022

Outcomes from an Australian COVID-19 virtual ward during Omicron wave

In a recent study posted to the medRxiv* preprint server, researchers in Australia characterized hospitalization volumes, patient epidemiological and clinical outcome data of patients admitted to virtual wards during the predominance of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant of concern (VOC) BA.1 sub-VOC and the Omicron BA.2 sub-VOC.

8 Nov 2022

Most echocardiography screenings for fetal congenital heart block fail to follow guidelines

New research presented this week at ACR Convergence 2022, the American College of Rheumatology's annual meeting, found that most echocardiography screening for fetal congenital heart block in anti-Ro- and anti-La-positive pregnancies did not follow recommended guidelines in one academic medical center.

8 Nov 2022

Dexamethasone News and Research

"Smart" sutures can detect inflammation and release drugs

Anticoronavirals: the development of COVID-19 therapies and the challenges that remain

Novel immunotherapy appears to be safe, well tolerated by children with relapsed brain tumors

Researchers develop a backpack-based myeloid cell therapy for MS patients

Early use of dexamethasone associated with reduced mortality in hospitalized COVID-19 requiring breathing support

Case report on Nocardia pseudobrasiliensis and SARS-CoV-2 concomitant infection

Candida auris infection without epidemiologic links to a prior outbreak

Using nanoparticles to encapsulate the medication may make corneal grafts more successful

The impact of specific comorbidities and overall multimorbidity on the three mechanistically distinct phases of COVID-19

New insights into the driving factors of COVID-19 dynamics in England

Combined glucocorticoid steroids and statin therapy may be safer for the treatment of preterm birth

New scan reliably detects primary aldosteronism, a common cause of hypertension

Scientists explore efficacy of small molecule drugs against severe COVID-19 in vitro

IU researchers uncover new ways to prevent serious side effects for breast cancer patients

No benefit of low dose apixaban following acute COVID-19

Study examines whether cortisone-like medicine can reduce pain after total knee arthroplasty

Exploring clinical characteristics and outcomes of hospitalized COVID-19 patients

Study aims to develop broad-spectrum antivirals against SARS-CoV-2 via drug repurposing strategies

Outcomes from an Australian COVID-19 virtual ward during Omicron wave

Most echocardiography screenings for fetal congenital heart block fail to follow guidelines

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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