Diabetes Mellitus News and Research

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Diabetes mellitus is a severe and debilitating chronic disease that develops in nearly 5 percent of the world’s population. People with this disease have a shortage of insulin or a reduced ability to use insulin, the hormone regulating blood glucose levels, which is normally produced by the pancreas. In the United States alone, an estimated 18 million people have diabetes, and each year about 1 million Americans are diagnosed with the disease. It is the sixth leading cause of death in the US and is responsible for over 200,000 deaths a year. Insulin-dependent (type I) diabetes accounts for around 10% of diabetics. For those patients, suffering from an inability of their pancreas to produce insulin, the only practical treatment possible is regular insulin replacement by multiple daily injections. Transplantation of a pancreas or pancreatic tissue would be beneficial to millions of such patients in that it would restore their normal ability to produce self insulin. Transplantation of human pancreas or pancreatic islets is a practiced and time-honored such therapeutic approach, but is extremely limited by the severe shortage of human donor organs. Tissera's R&D efforts in this domain are directed towards the development of a universally available and reliable source of animal fetal donor pancreatic precursor tissue, suitable for transplantation and eventual normal structural and functional growth in human diabetics.

Further Reading

New computational framework accurately predicts drug-drug and drug-food interactions

New computational framework accurately predicts drug-drug and drug-food interactions

Study finds link between pre-pregnancy fitness and lower risk of gestational diabetes

Study finds link between pre-pregnancy fitness and lower risk of gestational diabetes

Hydrogel may accelerate healing of diabetic ulcers

Hydrogel may accelerate healing of diabetic ulcers

Poor dental health may be related to increased diabetes risk

Poor dental health may be related to increased diabetes risk

Study finds low rates of preconception counseling among women of childbearing age with diabetes

Study finds low rates of preconception counseling among women of childbearing age with diabetes

Subset of immune cells critical for ensuring healthy weight gain, study shows

Subset of immune cells critical for ensuring healthy weight gain, study shows

Diabetes mellitus reclassified into 5 subtypes

Diabetes mellitus reclassified into 5 subtypes

Comparing low-fat and low-carb diets finds little difference

Comparing low-fat and low-carb diets finds little difference

Scientists visualize insulin receptor activation for the first time

Scientists visualize insulin receptor activation for the first time

Researchers find shortcomings in pregnancy and prenatal care for women with diabetes

Researchers find shortcomings in pregnancy and prenatal care for women with diabetes

New scanning technology could reduce number of biopsies on people with fatty liver disease

New scanning technology could reduce number of biopsies on people with fatty liver disease

Scientists discover the genetic cause of immune disorders

Scientists discover the genetic cause of immune disorders

Research reveals why patients with diabetes have poorer prognosis for prostate cancer

Research reveals why patients with diabetes have poorer prognosis for prostate cancer

Scientists discover how gene mutation affects T cell function to promote immune disorders

Scientists discover how gene mutation affects T cell function to promote immune disorders

Breastfeeding linked to lower risk of hypertension

Breastfeeding linked to lower risk of hypertension

Study finds higher risks for asymptomatic paroxysmal AF patients

Study finds higher risks for asymptomatic paroxysmal AF patients

Nano-encapsulation of bilirubin could enhance survival rates of pancreatic islet cells

Nano-encapsulation of bilirubin could enhance survival rates of pancreatic islet cells

First short-acting ‘follow-on’ insulin receives FDA approval to treat diabetes

First short-acting ‘follow-on’ insulin receives FDA approval to treat diabetes

Scientists use computer analysis to complete antibody blueprint

Scientists use computer analysis to complete antibody blueprint

Study reveals link of male-pattern baldness and premature graying with early heart disease

Study reveals link of male-pattern baldness and premature graying with early heart disease