Diabetes Mellitus News and Research

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Diabetes mellitus is a severe and debilitating chronic disease that develops in nearly 5 percent of the world’s population. People with this disease have a shortage of insulin or a reduced ability to use insulin, the hormone regulating blood glucose levels, which is normally produced by the pancreas. In the United States alone, an estimated 18 million people have diabetes, and each year about 1 million Americans are diagnosed with the disease. It is the sixth leading cause of death in the US and is responsible for over 200,000 deaths a year. Insulin-dependent (type I) diabetes accounts for around 10% of diabetics. For those patients, suffering from an inability of their pancreas to produce insulin, the only practical treatment possible is regular insulin replacement by multiple daily injections. Transplantation of a pancreas or pancreatic tissue would be beneficial to millions of such patients in that it would restore their normal ability to produce self insulin. Transplantation of human pancreas or pancreatic islets is a practiced and time-honored such therapeutic approach, but is extremely limited by the severe shortage of human donor organs. Tissera's R&D efforts in this domain are directed towards the development of a universally available and reliable source of animal fetal donor pancreatic precursor tissue, suitable for transplantation and eventual normal structural and functional growth in human diabetics.

Further Reading

Length of hospital stay and readmission likelihood increases by 2.9% in rural areas, review finds

Length of hospital stay and readmission likelihood increases by 2.9% in rural areas, review finds

Study investigates effects of glucose-lowering drug in preventing damage to the kidneys

Study investigates effects of glucose-lowering drug in preventing damage to the kidneys

Phase 3 ECHELON-2 clinical trial evaluating ADCETRIS plus CHP meets primary endpoint

Phase 3 ECHELON-2 clinical trial evaluating ADCETRIS plus CHP meets primary endpoint

Study aims to investigate antimicrobial resistance of uropathogenic E. coli from elderly patients

Study aims to investigate antimicrobial resistance of uropathogenic E. coli from elderly patients

FARXIGA receives positive results in Phase III DECLARE-TIMI 58 cardiovascular outcomes trial

FARXIGA receives positive results in Phase III DECLARE-TIMI 58 cardiovascular outcomes trial

CHMP issues positive opinion supporting use of Trelegy Ellipta in broader group of COPD patients

CHMP issues positive opinion supporting use of Trelegy Ellipta in broader group of COPD patients

New study reveals mechanisms that lead to cognitive decline in Type 2 diabetes

New study reveals mechanisms that lead to cognitive decline in Type 2 diabetes

Study aims to investigate risk factors for PPCs in surgical patients with gastric cancer

Study aims to investigate risk factors for PPCs in surgical patients with gastric cancer

EC approves update of INVOKANA and VOKANAMET labeling to include changes to indication statement

EC approves update of INVOKANA and VOKANAMET labeling to include changes to indication statement

Mothers with gestational diabetes mellitus have elevated risk of postpartum depression symptoms

Mothers with gestational diabetes mellitus have elevated risk of postpartum depression symptoms

Experts present arguments both against and supporting sugar consumption

Experts present arguments both against and supporting sugar consumption

Tandem Diabetes Care introduces t:slim X2 Insulin Pump with Basal-IQ Technology in the US

Tandem Diabetes Care introduces t:slim X2 Insulin Pump with Basal-IQ Technology in the US

Obesity in PTSD patients accounts for increased risk of type 2 diabetes mellitus

Obesity in PTSD patients accounts for increased risk of type 2 diabetes mellitus

New nuclear medicine test could improve care of patients with type 1 diabetes

New nuclear medicine test could improve care of patients with type 1 diabetes

Two new studies could improve treatment for patients with diabetes

Two new studies could improve treatment for patients with diabetes

CNDA approves KEYTRUDA for treatment of advanced melanoma

CNDA approves KEYTRUDA for treatment of advanced melanoma

Phase 3 study of KEYTRUDA monotherapy meets primary endpoint

Phase 3 study of KEYTRUDA monotherapy meets primary endpoint

Ferring announces FDA approval of ZOMACTON for injection in four new pediatric indications

Ferring announces FDA approval of ZOMACTON for injection in four new pediatric indications

People with type 2 diabetes more likely to suffer from breathlessness, restrictive lung disease

People with type 2 diabetes more likely to suffer from breathlessness, restrictive lung disease

Irregular metabolism of branched-chain amino acids may cause progression of type 2 diabetes

Irregular metabolism of branched-chain amino acids may cause progression of type 2 diabetes