Diabetes Mellitus News and Research

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Diabetes mellitus is a severe and debilitating chronic disease that develops in nearly 5 percent of the world’s population. People with this disease have a shortage of insulin or a reduced ability to use insulin, the hormone regulating blood glucose levels, which is normally produced by the pancreas. In the United States alone, an estimated 18 million people have diabetes, and each year about 1 million Americans are diagnosed with the disease. It is the sixth leading cause of death in the US and is responsible for over 200,000 deaths a year. Insulin-dependent (type I) diabetes accounts for around 10% of diabetics. For those patients, suffering from an inability of their pancreas to produce insulin, the only practical treatment possible is regular insulin replacement by multiple daily injections. Transplantation of a pancreas or pancreatic tissue would be beneficial to millions of such patients in that it would restore their normal ability to produce self insulin. Transplantation of human pancreas or pancreatic islets is a practiced and time-honored such therapeutic approach, but is extremely limited by the severe shortage of human donor organs. Tissera's R&D efforts in this domain are directed towards the development of a universally available and reliable source of animal fetal donor pancreatic precursor tissue, suitable for transplantation and eventual normal structural and functional growth in human diabetics.

Further Reading

Researchers uncover mechanism that leads to disorders in pancreatic development, infant diabetes

Researchers uncover mechanism that leads to disorders in pancreatic development, infant diabetes

Research suggests using combined OGTT and HbA1C tests to screen children at high risk of diabetes

Research suggests using combined OGTT and HbA1C tests to screen children at high risk of diabetes

World's leading heart failure congress sets new record for abstract submissions

World's leading heart failure congress sets new record for abstract submissions

Higher nut intake may help reduce risk of CVD, total cancer and all-cause mortality

Higher nut intake may help reduce risk of CVD, total cancer and all-cause mortality

TUM scientists show how diabetes damages small blood vessels around the heart

TUM scientists show how diabetes damages small blood vessels around the heart

New approach shows promise to prevent, treat cholesterol gallstone disease

New approach shows promise to prevent, treat cholesterol gallstone disease

FDA approves new nasal spray for adults who overproduce urine at night

FDA approves new nasal spray for adults who overproduce urine at night

AGA creates Obesity Practice Guide for effective weight management in obese patients

AGA creates Obesity Practice Guide for effective weight management in obese patients

Majority of physicians have poor knowledge of Charcot neuroarthropathy, survey finds

Majority of physicians have poor knowledge of Charcot neuroarthropathy, survey finds

World's largest GWAS on proteomics uncovers molecular mechanisms of complex diseases

World's largest GWAS on proteomics uncovers molecular mechanisms of complex diseases

Researchers provide new data and prospects for links between gut microbiota and depression

Researchers provide new data and prospects for links between gut microbiota and depression

Single high-fat meal can change energy metabolism of the liver, study finds

Single high-fat meal can change energy metabolism of the liver, study finds

Increased levels of physical activity linked to decreased insulin resistance, inflammation biomarkers

Increased levels of physical activity linked to decreased insulin resistance, inflammation biomarkers

Islets from rat-grown mouse pancreases can help reverse disease in diabetic mice

Islets from rat-grown mouse pancreases can help reverse disease in diabetic mice

Study finds new link between short sleep during pregnancy and gestational diabetes mellitus

Study finds new link between short sleep during pregnancy and gestational diabetes mellitus

Chemical modification improves release and availability of insulin, research shows

Chemical modification improves release and availability of insulin, research shows

Scientists isolate and characterize therapy-resistant dormant leukemia cells

Scientists isolate and characterize therapy-resistant dormant leukemia cells

Detecting inflammation in diabetic patients

Detecting inflammation in diabetic patients

New drug receives FDA approval to reduce risk of cardiovascular death in adults with diabetes

New drug receives FDA approval to reduce risk of cardiovascular death in adults with diabetes

Results of high-impact clinical trials could improve kidney-related medical care

Results of high-impact clinical trials could improve kidney-related medical care