Diabetes Mellitus News and Research

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Diabetes mellitus is a severe and debilitating chronic disease that develops in nearly 5 percent of the world’s population. People with this disease have a shortage of insulin or a reduced ability to use insulin, the hormone regulating blood glucose levels, which is normally produced by the pancreas. In the United States alone, an estimated 18 million people have diabetes, and each year about 1 million Americans are diagnosed with the disease. It is the sixth leading cause of death in the US and is responsible for over 200,000 deaths a year. Insulin-dependent (type I) diabetes accounts for around 10% of diabetics. For those patients, suffering from an inability of their pancreas to produce insulin, the only practical treatment possible is regular insulin replacement by multiple daily injections. Transplantation of a pancreas or pancreatic tissue would be beneficial to millions of such patients in that it would restore their normal ability to produce self insulin. Transplantation of human pancreas or pancreatic islets is a practiced and time-honored such therapeutic approach, but is extremely limited by the severe shortage of human donor organs. Tissera's R&D efforts in this domain are directed towards the development of a universally available and reliable source of animal fetal donor pancreatic precursor tissue, suitable for transplantation and eventual normal structural and functional growth in human diabetics.
Pregnancy at 40 and beyond is an independent risk factor for stillbirth

Pregnancy at 40 and beyond is an independent risk factor for stillbirth

High blood pressure in pregnancy may lead to heart disease

High blood pressure in pregnancy may lead to heart disease

Pioglitazone may help slow progression of artery wall thickening

Pioglitazone may help slow progression of artery wall thickening

Gout is a significant independent risk factor of heart attack

Gout is a significant independent risk factor of heart attack

Exercise for type 2 diabetes mellitus

Exercise for type 2 diabetes mellitus

Shock wave lithotripsy for renal calculi patients may increase the risk of hypertension and diabetes

Shock wave lithotripsy for renal calculi patients may increase the risk of hypertension and diabetes

New technique of corporeal excavation

New technique of corporeal excavation

Hysterectomy at the time of abdominal sacral colpopexy is associated with increased risk of mesh erosion in women on estrogen therapy

Hysterectomy at the time of abdominal sacral colpopexy is associated with increased risk of mesh erosion in women on estrogen therapy

Type 1 diabetes results from selective destruction of pancreatic islet beta cells

Type 1 diabetes results from selective destruction of pancreatic islet beta cells

Adolescents who live in poverty are more likely to be overweight

Adolescents who live in poverty are more likely to be overweight

Signaling pathways required for expansion of insulin-producing beta cells

Signaling pathways required for expansion of insulin-producing beta cells

Urgent effort underway to learn how diabetes increases heart disease risk

Urgent effort underway to learn how diabetes increases heart disease risk

Short acting insulin analogues versus regular human insulin in patients with diabetes mellitus

Short acting insulin analogues versus regular human insulin in patients with diabetes mellitus

Type 2 diabetics' urine acidity increases risk for kidney stones

Type 2 diabetics' urine acidity increases risk for kidney stones

Researchers reverse juvenile diabetes in animal model

Researchers reverse juvenile diabetes in animal model

Procedure cures some diabetic mice, but not in the way previously reported

Procedure cures some diabetic mice, but not in the way previously reported

Early periodontal treatment leads to lower medical costs

Early periodontal treatment leads to lower medical costs

Major biomarker candidates for Alzheimer's disease explored

Major biomarker candidates for Alzheimer's disease explored

Relationship between periodonta treatment and overall cost of care for several diseases

Relationship between periodonta treatment and overall cost of care for several diseases

Relationship between periodontal disease, obesity and insulin

Relationship between periodontal disease, obesity and insulin