Diabetic Nephropathy News and Research

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Diabetic nephropathy is kidney disease or damage that results as a complication of diabetes.

Mapping the genomic landscape of Type 2 diabetes

In the largest genome-wide association study to date on Type 2 diabetes, a team of international researchers, co-led by a University of Massachusetts Amherst genetic epidemiologist, has located 1,289 genetic markers associated with Type 2 diabetes (145 of which are newly identified) and generated risk scores for diabetes complications.

19 Feb 2024

Natural compounds show promise in modulating heme breakdown, offering new therapeutic avenues

Study explores the impact of natural compounds on bilirubin production and heme catabolic pathway modulation, highlighting their potential in treating neurodegenerative and cardiovascular diseases.

3 Jan 2024

Hederasaponin C may be a protective measure and novel therapeutic strategy for diabetic nephropathy

Announcing a new publication for Acta Materia Medica journal. There is great demand for the development of novel efficient therapeutic strategies or preventative measures to alleviate the life-threatening complications of type 2 diabetes.

21 Dec 2023

Citrus compounds show zesty promise in type 2 diabetes management

Citrus compounds show promise in type 2 diabetes management, reducing blood glucose and mitigating metabolic complications without a clear threshold in humans for bioflavonoid efficacy.

2 Nov 2023

Simple fingerprick blood test could help identify millions of people with undiagnosed diabetes

In 2019, there were almost 14 thousand diabetes-related deaths in the UK. That number looks set to rise. Britain currently has 4.3 million registered diabetics, but new analysis from London Medical Laboratory has revealed there are likely to be over one million Brits suffering from undiagnosed type 2 diabetes.

30 Sep 2023

New research sheds light on gut-kidney axis in diabetes and diabetic nephropathy

Researchers explored gut microbiota composition to evaluate the association between the microbes and diabetic clinical phenotypes.

2 Aug 2023

Is there a correlation between acute and chronic red wine intake and health?

Researchers examined the correlations between acute and chronic red wine (RW) intake and health.

18 Apr 2023

Insulin resistance increases retinopathy and nephropathy risk in young type 1 diabetics

A study published in the journal Cardiovascular Diabetology describes the relationship between estimated glucose disposal rate (eGDR) and retinopathy or kidney disease in young adults with type 1 diabetes.

22 Mar 2023

Researchers shine new light on a potential target for the treatment of diabetic nephropathy

The kidneys perform a critical role in the body by removing waste and excess fluid in the form of urine. In a condition known as diabetic nephropathy, complications from diabetes disrupt the ability of the kidneys to function properly.

15 Mar 2023

Japanese study reveals increase in incidence rates of renal replacement therapy attributed to nephrosclerosis

A new Japanese study reveals that the age-standardized incidence rates of end-stage kidney disease (ESKD) requiring renal replacement therapy (RRT) due to chronic glomerulonephritis and diabetic nephropathy has decreased, while rates due to nephrosclerosis have increased considerably between 2006 and 2020.

23 Dec 2022

Scientists identify group of genes shared between COVID-19 and diabetic kidney disease

Scientists identified five hub genes that might be associated with severe COVID-19 outcomes in patients with diabetic kidney disease.

17 Oct 2022

Studies to explore whether achieving beneficial ketone levels can improve metabolic health of military service members

A series of upcoming studies will explore whether the grind of active-duty military life and veterans' disproportionately high incidence of chronic illness could be tamed by lifestyle interventions designed to achieve a metabolic state of nutritional ketosis.

7 Sep 2022

Obesity may negatively affect kidney function in women with type 2 diabetes

Obesity may negatively affect kidneys function in people with type 2 diabetes, particularly in women, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

22 Feb 2022

Researchers link elevated levels of galectin-1 with increased risk of type 2 diabetes

Researchers at the University of Gothenburg now associate elevated levels of the protein galectin-1 with increased risk of developing type 2 diabetes about 18 years later.

8 Nov 2021

Injecting mice with pulmonary endothelial cells can reverse symptoms of emphysema

Researchers at Weill Cornell Medicine and NewYork-Presbyterian in New York have discovered that injecting mice with pulmonary endothelial cells-the cells that line the walls of blood vessels in the lung-can reverse the symptoms of emphysema.

21 Jul 2021

Study reveals mechanisms by which SGLT2 inhibitors produce renoprotective effect

SGLT2 inhibitors (gliflozins) were developed as oral antidiabetics. They enhance urinary glucose excretion by inhibiting SGLT-2 (sodium-dependent glucose co-transporter-2) in the renal tubuli.

8 Jun 2021

New enzyme may help curb chronic kidney disease

University of South Australia researchers have identified an enzyme that may help to curb chronic kidney disease, which affects approximately 700 million people worldwide.

4 May 2021

New review supports stricter control of HbA1C levels among children with type 1 diabetes

Diabetes is characterized by elevated levels of sugar or glucose (hyperglycemia) in the blood. This occurs due to the lack of the hormone insulin in type 1 diabetes, and to reduced insulin levels in combination with insulin resistance in type 2 diabetes.

15 Jan 2021

Phase 2 clinical trial to examine the effects of razuprotafib on COVID-19 patients

Researchers at the University of Cincinnati and UC Health will host a Phase 2 clinical trial (NCT04511650) to examine the effects of a drug that targets blood vessel inflammation and injury in patients with COVID-19.

22 Sep 2020

Large-scale analysis of Alport syndrome reveals the effectiveness of existing treatments

A large-scale analysis of the clinical characteristics of Alport syndrome in Japanese patients has revealed that the effectiveness of existing treatment with ACE inhibitors and/or angiotensin receptor blockers (RAS inhibitors) varies depending on the type of mutation in the syndrome's causal gene (COL4A5).

7 Aug 2020