Disease Modeling News and Research

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Researchers develop a cell line to address the challenges facing cellular modeling of disease

Bill Skarnes and team established and characterized a stable iPSC line, KOLF2.1J, to act as a high-quality baseline platform for modeling human disease.

3 Feb 2023

CuSTOM; Creating a healthier society by accelerating the translation of organoid technology

In this interview, we speak to Magdalena Kasendra at the CuSTOM Accelerator, about the organoid technology and how it has the power the revolutionize healthcare.

From Society for Laboratory Automation and Screening (SLAS) 1 Feb 2023

Borrowing from weather and climate science models can help us prepare for future pandemics

A new study determines how insights from the climate and weather research field can improve the forecasting of pandemics.

22 Jan 2023

Launch of FAU Stiles-Nicholson Brain Institute heralds a new era in neuroscience research, education

Florida Atlantic University celebrated the opening of the FAU Stiles-Nicholson Brain Institute at FAU's John D. MacArthur Campus in Jupiter today with a ribbon-cutting ceremony.

20 Jan 2023

Shielding measures conferred protection to pregnant individuals in early COVID-19 pandemic

Individuals who were already pregnant at the beginning of the COVID-19 pandemic had a 50 percent lower exposure to SARS-CoV-2 compared with those who became pregnant after the pandemic began and the general population, according to a new model created by Weill Cornell Medicine, NewYork-Presbyterian and University of Oxford investigators.

16 Dec 2022

Study identifies a potential pharmacological target for treating COVID-19-associated heart failure

Researchers at the University of Maryland School of Medicine's (UMSOM) Center for Precision Disease Modeling identified how a specific protein in SARS-CoV-2, the virus responsible for COVID-19, damages heart tissue. They then used a drug to reverse the toxic effects of that protein on the heart.

8 Nov 2022

Beyond vaccines: emerging technologies capable of unlocking the promise of biologically targeted mRNA therapeutics

Researchers reviewed technology advancements that will unlock the promise of biologically targeted messenger ribonucleic acid (mRNA) therapeutics beyond vaccines.

7 Nov 2022

Understanding the potential applications of stem cell research

To mark Stem Cell Awareness Day on October 12, 2022, COST is highlighting a network of researchers working to foster greater understanding about stem cell research and potential applications for millions of people suffering from incurable diseases and injury.

12 Oct 2022

New modeling system identifies potential therapeutics for autosomal recessive polycystic kidney disease

Organoids-;lab grown cells or tissues that resemble organs-;serve as a new tool for disease modeling, but researchers often have difficulty replicating the biophysical conditions in which the organs operate within the body.

22 Sep 2022

The potential for measles and rubella elimination globally

Researchers modeled the probability of eradication of measles and rubella by 2100.

19 Sep 2022

Inventia Life Science partners with Xylyx Bio to develop tissue-specific, digitally-printed bioinks for drug discovery

Inventia Life Science and Xylyx Bio today announced their strategic partnership following promising results developing more realistic, scalable, and reproducible 3D cell cultures for drug discovery and biomedical research.

From Inventia Life Science 16 Aug 2022

Human intestine-on-a-chip for modeling intestinal injury associated with a pediatric inflammatory disorder

News-Medical speaks to Dr. Cicely Fadel and Amir Bein about their latest research which involved the development of an Environmental Enteric Dysfunction (EED) Chip that reveals the effects of nutrition and genetics on disease in children

8 Aug 2022

Turning to Organ-on-a-Chip Studies for the Future of Drug Discovery

In this interview, we speak to Tom Kostrzewski, VP of Science and Technology at CN Bio, about their organ-on-a-chip product and the future of drug discovery.

From CN-Bio 3 Aug 2022

Frequent, regular rapid antigen testing plus isolation could cut COVID-19 risk among groups of people

Among oil-rig workers, shipping crews, and other groups of people who work closely together, COVID-19 can spread like wildfire. Yet trying to prevent spread with long quarantines can be just as disruptive.

15 Jul 2022

Scientists prove the “neuroprotective” function of p62 protein in a mouse model

Neurodegenerative diseases like Alzheimer’s and Parkinson’s are defined by pathogenic accumulation of toxic proteins in the brain.

1 Jul 2022

Techniques used in weather forecasting can be repurposed to assess risk of COVID-19 exposure

Techniques used in weather forecasting can be repurposed to provide individuals with a personalized assessment of their risk of exposure to COVID-19 or other viruses, according to new research published by Caltech scientists.

23 Jun 2022

Disease ecologist receives $3.5 million to take modeling to the next level with EpiMoRPH

Mathematical modeling-;which combines math, statistics, computing and data-;is a critical tool for public health professionals, who use it to study how diseases spread, predict the future course of outbreaks and evaluate strategies for controlling epidemics.

18 Jun 2022