Disease Modeling News and Research

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Hairy human skin grown from pluripotent stem cells

Building on years of groundbreaking discoveries in stem cell research, scientists from Indiana University School of Medicine and Harvard Medical School have determined how to grow hairy skin using human stem cells--developing one of the most complex skin models in the world.

4 Jun 2020

New study investigates the effect of asymptomatic COVID-19 transmission

COVID-19's rapid spread throughout the world has been fueled in part by the virus' ability to be transmitted by people who are not showing symptoms of infection.

13 May 2020

New computer modeling systems to predict spread of SARS-CoV-2 virus

Joe Mihaljevic, mathematical epidemiologist and assistant professor in Northern Arizona University's School of Informatics, Computing, and Cyber Systems, is leading a new project to create computer modeling systems to predict outcomes of the spread of the SARS-CoV-2 virus, which causes COVID-19, across four northern Arizona counties--Coconino, Navajo, Apache and Mohave.

4 May 2020

"Stratify-and shield" a potential alternative to COVID-19 lockdowns

Researchers in Scotland who have evaluated a “stratify-and shield” policy for combating coronavirus disease 2019 (COVID-19) in the UK say it is time to consider the approach as an alternative to social distancing seriously.

3 May 2020

COVID-19 Simulator shows how lifting or extending social-distancing measures will impact states

A new online tool, COVID-19 Simulator, developed by researchers at Massachusetts General Hospital and Georgia Tech can help policy makers see how lifting or extending different social-distancing measures at various times can impact each state in terms of COVID-19 cases, hospitalizations, and deaths.

29 Apr 2020

Exploring the use of stem cells for COVID-19 disease

The coronavirus disease (COVID-19) has ravaged across the, infecting more than 3.11 million people in just over four months. As the virus continues to spread, scientists are struggling to find an effective treatment for the infection. Now, a breakthrough discovery on stem cells could help in the battle against COVID-19.

28 Apr 2020

Study marks a major step towards beta cell replacement therapy

The loss of insulin-secreting beta cells by autoimmune destruction leads to type 1 diabetes. Clinical islet cell transplantation has the potential to cure diabetes, but donor pancreases are rare.

28 Apr 2020

Researchers uncover mechanism by which gene mutations potentially give rise to kidney disease

Researchers from the Center for Precision Disease Modeling at the University of Maryland School of Medicine have uncovered a mechanism that appears to explain how certain genetic mutations give rise to a rare genetic kidney disorder called nephrotic syndrome.

5 Apr 2020

OXGENE and The Native Antigen Company Announce Collaboration to Increase COVID-19 Antigen Production for Diagnostic Kits and Vaccine Development

OXGENE™ and The Native Antigen Company today announced a collaboration to scale up production of SARS-CoV-2 (COVID-19) reagents.

2 Apr 2020

Putting an end to the pandemic

From the plagues of medieval Europe to the influenza pandemic of 1918, the specter of the next public health disaster has gripped the minds of scientists, captivated the imaginations of writers and vexed conspiracy theorists.

1 Apr 2020

Organ-Chips provide human-relevant insights into diseases and toxicity mechanisms

Organs-on-Chips technology has entered the mainstream and has reached 150 installations for use by researchers across many industries, including 10 of the top 25 biopharmaceutical companies, as well as leading international academic research centers and U.S. government laboratories, including the U.S. FDA through a collaborative agreement and the U.S. Army.

20 Mar 2020

UC researchers identify populations most at risk of overdosing on opiates

Researchers at the University of Cincinnati are helping to identify those most at risk in Ohio of overdosing on opiates.

19 Mar 2020

Prize-winning research offers a promising approach to improve regenerative medicine

Joana Neves is the 2019 grand prize winner of the Sartorius & Science Prize for Regenerative Medicine & Cell Therapy, for work that offers a promising approach to improve the outcome of regenerative stem cell-based therapies aimed at delaying age-related degenerative diseases.

12 Mar 2020

Many science investigations launch to the International Space Station

A variety of science investigations, along with supplies and equipment, launch to the International Space Station on the 20th SpaceX commercial resupply services mission.

2 Mar 2020

Researchers develop multi-organ-on-a-chip for drug toxicity screening

Researchers in the US have developed a new multi-organ-on-a-chip to test how new drugs affect the human body's vital organs.

2 Mar 2020

Tulane establishes COVID-19 research program to develop a vaccine and test treatments

From working to develop one of the first nonhuman primate models for the 2019 novel coronavirus disease (COVID-19) to designing new therapeutic strategies and nanotechnology-based tests to rapidly diagnose infections, researchers at Tulane University are responding across disciplines to the emerging coronavirus epidemic.

21 Feb 2020

Scientists create world’s first model of pituitary disease using human iPS cells

Researchers at Kobe University's Graduate School of Medicine have developed the world's first congenital pituitary hypoplasia model using patient-derived iPS cells.

14 Feb 2020

The U.S. can erase cervical cancer in two decades

Cervical cancer is preventable, thanks to the development of the human papillomavirus (HPV) vaccine. Various strains of HPV, a sexually transmitted infection, play a significant role in the event of cervical cancer. Now, the U.S. can eradicate cervical cancer within the next 20 years, according to a new study.

11 Feb 2020

Renal stem cells can be isolated from urine

Researchers from the Institute for Stem Cell Research and Regenerative Medicine at the medical faculty of Heinrich Heine University-Duesseldorf under the directorship of Prof. Dr. James Adjaye have developed a protocol for the reproducible isolation and characterization of kidney stem cells, urine-derived renal progenitor cells (UdRPCs) from donors of distinct ages, gender and ethnicity.

4 Feb 2020

Gene-editing taken to advanced levels in human stem cells

A new study published in the journal Stem Cell Reports in January 2020 reports the use of an adaptation to a commonly used gene editing technology to achieve a more than 900% increase in efficiency.

30 Jan 2020