Dopaminergic News and Research

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Scientists identify new therapeutic target for depression

Depression is one of the most widespread disorders that affects society, according to the World Health Organization. In fact, it is estimated that 4 million people are affected in Spain.

22 May 2019

Southern Research team aims to discover new, safer antimalarial medicines

Scientists at Southern Research's Drug Discovery division have joined the fight against malaria through efforts aimed at discovering new drugs and improving the safety and efficacy of current antimalarial medicines.

22 May 2019

Neonatal exposure to nicotine alters neurons, predisposes brain to addiction in adulthood

Neonatal exposure to nicotine alters the reward circuity in the brains of newborn mice, increasing their preference for the drug in later adulthood, report researchers at University of California San Diego School of Medicine in a study published "in press" April 24, 2019 in Biological Psychiatry.

22 May 2019

Fruit fly study shows role of unexplored neural circuit in modulating memory strength

Learning to avoid negative experiences requires an interplay of two distinct brain circuits, one to interpret "Yikes!" and drive learning, and the other, unexpectedly, to dial in the strength of that memory, a new fruit fly study shows.

15 May 2019

Damaged mitochondria use 'eat me' signals for mitophagy

When mitochondria become damaged, they avoid causing further problems by signaling cellular proteins to degrade them.

12 Apr 2019

Researchers discover several genes linked to increased use of alcohol and tobacco

The use of alcohol and tobacco is closely linked to several diseases, and is a contributing factor in many deaths.

21 Feb 2019

Study finds neuromelanin-sensitive MRI as potential biomarker for psychosis

Researchers have shown that a type of magnetic resonance imaging -- called neuromelanin-sensitive MRI is a potential biomarker for psychosis.

18 Feb 2019

UVA scientists find potential explanation for mysterious cell death in Alzheimer’s, Parkinson’s

Scientists at the University of Virginia School of Medicine have identified a potential explanation for the mysterious death of specific brain cells seen in Alzheimer’s, Parkinson’s and other neurodegenerative diseases.

15 Feb 2019

Researchers identify blood-based biomarkers of Parkinson's disease

Researchers at University of California San Diego School of Medicine and Arizona State University have received funding from The Michael J. Fox Foundation for Parkinson's Research to launch a multi-year, $1.7-million effort to identify blood-based biomarkers of Parkinson's disease, which could improve care and accelerate new treatments for the neurodegenerative disorder, which affects nearly 1 million Americans, with 60,000 new cases diagnosed annually.

5 Feb 2019

Study reveals link between dopamine and reward responses in humans when listening to music

A new study published in Proceedings of the National Academy of Sciences (PNAS), reveals a causal link between dopamine and the reward responses in humans when listening to music.

25 Jan 2019

Study suggests key role for glial cells in Parkinson's disease

A team of scientists led by Prof. Antonella Consiglio from the IDIBELL and the University of Barcelona, and Prof. Angel Raya from the Center of Regenerative Medicine of Barcelona have discovered that defective versions of human brain cells called astrocytes are linked to the buildup of a toxic protein that is one the hallmarks of Parkinson's disease.

16 Jan 2019

New study describes various gene therapy strategies for treating Parkinson's disease

Parkinson's disease is a neurodegenerative disorder characterized by motor and nonmotor deficits majorly caused by the loss of dopaminergic cells in the Substantia Nigra pars compacta as well as the destruction of nigrostriatal pathway.

28 Dec 2018

Study suggests dopamine release in the brain occurs twice per meal

We know a good meal can stimulate the release of the feel-good hormone dopamine, and now a study in humans from the Max Planck Institute for Metabolism Research in Germany suggests that dopamine release in the brain occurs at two different times: at the time the food is first ingested and another once the food reaches the stomach.

28 Dec 2018

GABA cells help fight alcohol dependence, study finds

Scientists of the Higher School of Economics, Indiana University, and École normale supérieure clarified how alcohol influences the dopamine and inhibitory cells in the midbrain that are involved in the reward system and the formation of dependency on addictive drugs.

19 Dec 2018

International study of ADHD at genomic scale

An international study, focused on the analysis of the genome of more than 50,000 people worldwide, has identified twelve specific fragments of DNA related to the vulnerability of the attention deficit hyperactivity disorder.

26 Nov 2018

Smokers at greater risk of schizophrenia and psychotic disorders

A team of researchers from University of Queensland have found that tobacco use is associated with an increased risk of psychotic disorders including schizophrenia.

21 Nov 2018

First fully personalized tissue implant engineered from patient's own materials and cells

In a new study, Tel Aviv University researchers reveal how they invented the first fully personalized tissue implant, engineered from a patient's own materials and cells. The new technology makes it possible to engineer any kind of tissue implant from one small fatty tissue biopsy.

13 Nov 2018

Study of gaze fixation in monkeys reveals role of dopamine neurons in response inhibition

A University of Tsukuba-led study of gaze fixation in monkeys and their refusal to redirect the gaze onto a target in return for a reward reveals that dopamine neurons are key to inhibiting preplanned actions.

8 Nov 2018

Newly discovered compound shows potential for treating Parkinson's disease

A joint research group centered around Professor Hideyuki Okano and Associate Professor Jun Kohyama, Department of Physiology of the Keio University School of Medicine, together with a research group of Eisai Co., Ltd. has identified a compound that has the potential to be a treatment for Parkinson's disease by using dopaminergic neurons differentiated from induced pluripotent stem (iPS) cells from patients with familial Parkinson's disease.

19 Oct 2018

Study: Alterations in genes encoding proteins contribute to ADHD development

A team from I.M. Sechenov First Moscow State Medical University together with foreign colleagues analyzed the genomes of several families that have members with ADHD.

12 Oct 2018

Dopaminergic News and Research

Scientists identify new therapeutic target for depression

Southern Research team aims to discover new, safer antimalarial medicines

Neonatal exposure to nicotine alters neurons, predisposes brain to addiction in adulthood

Fruit fly study shows role of unexplored neural circuit in modulating memory strength

Damaged mitochondria use 'eat me' signals for mitophagy

Researchers discover several genes linked to increased use of alcohol and tobacco

Study finds neuromelanin-sensitive MRI as potential biomarker for psychosis

UVA scientists find potential explanation for mysterious cell death in Alzheimer’s, Parkinson’s

Researchers identify blood-based biomarkers of Parkinson's disease

Study reveals link between dopamine and reward responses in humans when listening to music

Study suggests key role for glial cells in Parkinson's disease

New study describes various gene therapy strategies for treating Parkinson's disease

Study suggests dopamine release in the brain occurs twice per meal

GABA cells help fight alcohol dependence, study finds

International study of ADHD at genomic scale

Smokers at greater risk of schizophrenia and psychotic disorders

First fully personalized tissue implant engineered from patient's own materials and cells

Study of gaze fixation in monkeys reveals role of dopamine neurons in response inhibition

Newly discovered compound shows potential for treating Parkinson's disease

Study: Alterations in genes encoding proteins contribute to ADHD development

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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