Dopaminergic News and Research

RSS

Administration of two proteins shown to counteract neurodegeneration in Parkinson's disease

A combination therapy made up of two neurotrophic factors can reduce the degenerative effects of Parkinson’s disease, shows new research.

15 Jan 2018

Synergy between two neurotrophic factors exerts beneficial effect in early phase of Parkinson’s disease

Parkinson's disease is currently the second most widespread neurogenerative pathology. Current therapies are mainly of a replacement type and pose problems in the long term, so the challenge is to establish an early diagnosis and develop neuroprotective and neurorestorative therapies that will allow the symptoms of the disease to be slowed down or even reversed.

12 Jan 2018

Study finds new brainstem changes in Parkinson’s disease

A pioneering study has found that patients with Parkinson's disease have more errors in the mitochondrial DNA within the brainstem, leading to increased cell death in that area.

4 Jan 2018

Combining virtual reality and treadmill training improves neuroplasticity in Parkinson's patients

A new Tel Aviv University study suggests that a therapy that combines Virtual Reality and treadmill exercise dramatically lowers the incidence of falling among Parkinson's patients by changing the brain's behavior and promoting beneficial brain plasticity, even in patients with neurodegenerative disease.

28 Nov 2017

Scientists find key that allows neural differentiation of microRNA-deficient pluripotent stem cells

The more than 200 different types of human cells have the same DNA but express different ensembles of genes. Each cell type was derived from embryonic stem cells, which are called pluripotent stem cells because they can differentiate to all those different cell fates.

15 Nov 2017

Research suggests possibility of preventing and treating Parkinson's disease using licorice extract

DGIST's research team led by Dr. Yun-Il Lee in Well-Aging Research Center has identified a new mechanism of inhibition of dopaminergic neuronal apoptosis and suggested the possibility of preventing and treating Parkinson's disease.

8 Nov 2017

ACADIA Pharmaceuticals announces results from Phase II study of antipsychotic in Alzheimer's disease psychosis

ACADIA Pharmaceuticals Inc., a biopharmaceutical company focused on the development and commercialization of innovative medicines to address unmet medical needs in central nervous system (CNS) disorders, today announced the presentation of data from the Phase II -019 Study of pimavanserin in Alzheimer's disease psychosis at the 10th Clinical Trials on Alzheimer's Disease meeting in Boston.

3 Nov 2017

Reprogrammed stem cell therapy shows promise in Parkinson's

Japanese investigators have found that their experimental stem cell therapy for Parkinson’s disease actually works. In their experimental therapy, the team of researchers “reprogrammed” stem cells to make them neurons and implanted them into the brain of monkeys with a version of Parkinson’s disease. Stem cell therapy showed improvement of symptoms in these patients and was found to be safe. The study was published yesterday, 30th August 2017 in Nature.

30 Aug 2017

Bacterial community in the gut of Parkinson's patients differs from that of healthy people

Parkinson's disease is an insidious disease: by the time it manifests as the typical motor dysfunctions such as tremors or muscle rigidity, portions of the brain have already been irreversibly destroyed.

29 Aug 2017

Traumatic brain injuries in kids could be risk-factor for alcohol abuse in later life

Researchers at Ohio State University have surveyed previous studies to investigate the relationship between traumatic brain injuries and alcohol abuse.

14 Aug 2017

Low-dose anxiolytics can ameliorate social disadvantage related to trait anxiety

Psychologists speak of anxiety in two forms: "state" anxiety, which refers to anxiety arising from a particular situation; and "trait" anxiety, which refers to anxiety as part of a person's overall personality.

18 Jul 2017

New approaches to early detection of Parkinson's disease on the horizon

Detecting Parkinson's disease before non-reversible symptoms occur: New approaches to early detection are meant to ensure just that. They are based on detection of alpha-synuclein in the skin or intestines.

24 Jun 2017

Cell cultures in petri dishes open new doors to brain research

The most complex organ in humans is the brain. Due to its complexity and, of course, for ethical reasons, it is extremely difficult to do scientific experiments on it - ones that could help us to understand neurodegenerative diseases like Parkinson's, for example.

13 Apr 2017

MPA approves Renishaw study into chronic drug delivery system in Parkinson's patients

The Medicines Agency of Sweden, MPA, has authorised Herantis Pharma Plc and Renishaw plc’s randomised, placebo-controlled Phase 1-2 clinical study, for the investigation of Cerebral Dopamine Neurotrophic Factor (CDNF) and Renishaw’s chronic drug delivery system, in Parkinson’s patients.

4 Apr 2017

Bowel cancer medication could help treat patients with early-onset Parkinson's disease, study suggests

People with certain forms of early-onset Parkinson's disease could potentially benefit from taking a medication used to treat certain forms of cancer, according to new research by University of Leicester scientists and funded by the Medical Research Council.

14 Mar 2017

Researchers identify potential alcoholism mechanisms linked to dynamical dopamine imbalance

Researchers from the Higher School of Economics, Ecole Normale Supérieure, Paris, Indiana University and the Russian Academy of Sciences Nizhny Novgorod Institute of Applied Physics have identified potential alcoholism mechanisms, associated with altered dopaminergic neuron response to complex dynamics of prefrontal cortex neurones affecting dopamine release.

9 Mar 2017

Dopaminergic News and Research

Administration of two proteins shown to counteract neurodegeneration in Parkinson's disease

Synergy between two neurotrophic factors exerts beneficial effect in early phase of Parkinson’s disease

Study finds new brainstem changes in Parkinson’s disease

Combining virtual reality and treadmill training improves neuroplasticity in Parkinson's patients

Scientists find key that allows neural differentiation of microRNA-deficient pluripotent stem cells

Research suggests possibility of preventing and treating Parkinson's disease using licorice extract

ACADIA Pharmaceuticals announces results from Phase II study of antipsychotic in Alzheimer's disease psychosis

Reprogrammed stem cell therapy shows promise in Parkinson's

Bacterial community in the gut of Parkinson's patients differs from that of healthy people

Traumatic brain injuries in kids could be risk-factor for alcohol abuse in later life

Low-dose anxiolytics can ameliorate social disadvantage related to trait anxiety

New approaches to early detection of Parkinson's disease on the horizon

Cell cultures in petri dishes open new doors to brain research

MPA approves Renishaw study into chronic drug delivery system in Parkinson's patients

Bowel cancer medication could help treat patients with early-onset Parkinson's disease, study suggests

Researchers identify potential alcoholism mechanisms linked to dynamical dopamine imbalance

Red hair-related gene variant may contribute to link between melanoma and Parkinson's disease

Neurotrophic factor GDNF regulates dopamine neurons in the brain, research shows

Study strengthens therapeutic potential for niacin-based diet in treatment of Parkinson's disease

Music may regulate mood, emotional responses at behavioral and neuronal level

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

Latest News