Drug delivery is a term that refers to the delivery of a pharmaceutical compound into the body. Most common methods of delivery include the preferred non-invasive oral (through the mouth), nasal, pneumonial (inhalation), and rectal routes. Much research is now focussing on nanotechnology as a drug delivery method.
Glioblastoma is the most aggressive cancer that originates in the brain. Current therapies can slow the disease, but more often than not can't cure it.
Fluence Analytics, a manufacturer of realtime, industrial and laboratory monitoring systems, today announced the launch of ARGEN, a patented protein and polymer stability monitoring product. By utilizing continuous light scattering measurements, ARGEN yields a unique information stream which reduces discovery and formulation and development times.
Stand Up To Cancer has awarded a $2.5 million SU2C CatalystR grant to the Translational Genomics Research Institute to investigate a revolutionary new method of treating pancreatic cancer, one of the most aggressive of all cancers.
DNA evolved to store genetic information, but in principle this special, chain-like molecule can also be adapted to make new materials. Chemists at The Scripps Research Institute have now published an important demonstration of this repurposing of DNA to create new substances with possible medical applications.
The Pittcon Program Committee is pleased to announce this year’s recipients of 13 prestigious awards honoring scientists who have made outstanding contributions to analytical chemistry and applied spectroscopy. Each award will be presented in a scheduled symposium during Pittcon 2018, the world’s leading conference and exposition for laboratory science, which will be held February 26-March 1, Orange County Convention Center, Orlando, Florida.
RCSI is leading an international team of scientists on a major research study that aims to train the next generation of brain cancer researchers.
Researchers in China who assessed self-monitoring of blood glucose behavior among nearly 19,000 patients with type 2 diabetes treated with oral medications reported very low SMBG rates both before and after the patients began treatment with basal insulin, although the data showed an increase in mean SMBG frequency after 6 months and the percentage of patients who never monitored their blood glucose decreased.
Scientists have helped provide a way to better understand how to enable drugs to enter the brain and how cancer cells make it past the blood brain barrier. The brain is protected by the near-impermeable blood brain barrier, a fortress which protects the brain but which also prevents the treatment of brain diseases, including brain tumors.
Bacteria release membrane-derived vesicles (MVs), which are small particles that can transport virulence factors to neighboring bacteria or to the cells of a mammalian host. This special MV-based system for delivering toxic proteins and nucleic acids in a protected manner to the target cells may have different specific functions depending on whether the bacterium acts as an extracellular or intracellular pathogen.
Engineers from MIT have devised a new method that could benefit millions by allowing delivery of more than one drug or vaccine with a single injection. They have designed a new type of drug-carrying particle that when injected could deliver the drugs or vaccines in blood over a period of time as desired.
For a cancer drug to be successful, it needs to reach the malignant tumor site. Researchers in Japan have now found a way for increasing the effectiveness of drug delivery to certain types of brain tumors, by packing epirubicin, a known antitumor agent, in specially designed polymeric micelles.
When environmental and soil chemist Baoshan Xing at the University of Massachusetts Amherst began reading in 2014 that a new, two-dimensional material known as layered black phosphorous (BP) was gaining the attention of biomedical researchers for use in drug delivery systems and tumor photothermal therapy, he was both intrigued and concerned.
Less than a decade ago, the U.S. Department of Defense established the Armed Forces Institute of Regenerative Medicine I with a multimillion dollar grant to focus research centered on regenerative medicine for the treatment of battlefield injuries and selected Rutgers University-New Brunswick to lead the civilian research program.
With increasing scientific and medical interest in communication with the nervous system, demand is growing for biomedical devices that can better record and stimulate the nervous system, as well as deliver drugs and biomolecules in precise dosages.
Nothing seemed to help the patient — and hospice staff didn't know why. They sent home more painkillers for weeks. But the elderly woman, who had severe dementia and incurable breast cancer, kept calling out in pain.
An article published in Experimental Biology and Medicine (Volume 242, Issue 14, August 2017) reports that a plant virus-based system can be used to deliver anti-cancer drugs.
Nanotechnology has made another breakthrough at the University of California San Diego. For the first time the researchers have shown that micromotors or microscopic robots could be used to treat a bacterial infection in the stomach in mice models win the laboratory.
Vijaya B. Kolachalama, PhD, assistant professor of medicine at Boston University School of Medicine, has received a Scientist Development grant from the American Heart Association.
Chapman University’s four-year-old School of Pharmacy continues its aggressive growth in federal grant awards.
According to latest research, gold particles can be effective in certain cancer therapy areas. Researchers at the Edinburgh University report in their new study that gold particles can help enhance the effectiveness of the agents used for lung cancer cells. The study is published in the scientific journal Angewandte Chemie.