Drug Discovery News and Research

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The drug discovery process begins with recognizing a disease or clinical condition in which there is a lack of adequate medical treatment. Once a potential drug has been identified, pre-clinical research can begin. This process includes several stages; the first of which involves identifying and validating the prospective drug’s target through assay development, high throughput screening, hit identification and finally, lead optimization. Once the pre-clinical process is complete, the newly synthesized drug candidate is selected for future clinical development.
TARA's organ-on-a-chip technology can directly measure in vivo cardiac performance, study shows

TARA's organ-on-a-chip technology can directly measure in vivo cardiac performance, study shows

LUNAC announces spin out with £2.65 million funding to develop advanced anticoagulants

LUNAC announces spin out with £2.65 million funding to develop advanced anticoagulants

PhoreMost and Sentinel Oncology expand partnership to advance novel allosteric PLK1 inhibitor

PhoreMost and Sentinel Oncology expand partnership to advance novel allosteric PLK1 inhibitor

TACC announces role as key collaborator in NIH grant to study chronic pain and opioid dependence

TACC announces role as key collaborator in NIH grant to study chronic pain and opioid dependence

Dopamine D2 receptor modulates Wnt expression, controls cell proliferation

Dopamine D2 receptor modulates Wnt expression, controls cell proliferation

New computational model could help in the development of anti-cancer drugs

New computational model could help in the development of anti-cancer drugs

Turbine secures institutional financing of €3m to expand potential of simulation-first drug discovery

Turbine secures institutional financing of €3m to expand potential of simulation-first drug discovery

New biomarker discovered in cancer stem cells

New biomarker discovered in cancer stem cells

Horizon Discovery announces divestment of animal models business to Envigo

Horizon Discovery announces divestment of animal models business to Envigo

Thermo Scientific Aquilos 2 Cryo-FIB reduces sample preparation time

Thermo Scientific Aquilos 2 Cryo-FIB reduces sample preparation time

Glutamine-blocking compound slows cancer growth, unleashes anti-tumor immune response

Glutamine-blocking compound slows cancer growth, unleashes anti-tumor immune response

PromoCell now offers wide range of in vitro disease models for developing new therapies

PromoCell now offers wide range of in vitro disease models for developing new therapies

Fluidic Analytics announces 'Be the One-With a great idea' competition ahead of Fluidity One-W launch

Fluidic Analytics announces 'Be the One-With a great idea' competition ahead of Fluidity One-W launch

Sphere Fluidics and Peak Analysis and Automation introduce integrated micro-plate handling and single cell analysis capabilities

Sphere Fluidics and Peak Analysis and Automation introduce integrated micro-plate handling and single cell analysis capabilities

MD Anderson, Artios Pharma and ShangPharma collaborate for ATR inhibitor program

MD Anderson, Artios Pharma and ShangPharma collaborate for ATR inhibitor program

AnaBios receives IDIQ contract to assess drug safety related to cardiac function

AnaBios receives IDIQ contract to assess drug safety related to cardiac function

New stem cell transplant lowers complications for patients with acute blood cancers

New stem cell transplant lowers complications for patients with acute blood cancers

Researchers successfully treat pain using nanoparticles to deliver a non-opioid medication

Researchers successfully treat pain using nanoparticles to deliver a non-opioid medication

Nanoparticle drug delivery enhances and prolongs pain relief in animal models

Nanoparticle drug delivery enhances and prolongs pain relief in animal models

How venom from marine cone snails can be used in pain therapy

How venom from marine cone snails can be used in pain therapy