Drug Discovery News and Research

RSS
The drug discovery process begins with recognizing a disease or clinical condition in which there is a lack of adequate medical treatment. Once a potential drug has been identified, pre-clinical research can begin. This process includes several stages; the first of which involves identifying and validating the prospective drug’s target through assay development, high throughput screening, hit identification and finally, lead optimization. Once the pre-clinical process is complete, the newly synthesized drug candidate is selected for future clinical development.
New fluorescent sensor can detect migrating cancer cells

New fluorescent sensor can detect migrating cancer cells

Southern Research team aims to discover new, safer antimalarial medicines

Southern Research team aims to discover new, safer antimalarial medicines

Electron microscopy project could revolutionize the search for new drugs

Electron microscopy project could revolutionize the search for new drugs

Marine natural compounds could be potential treatments for triple negative breast cancer

Marine natural compounds could be potential treatments for triple negative breast cancer

CRISPR uncovers which gene fusions are critical for growth of cancer cells

CRISPR uncovers which gene fusions are critical for growth of cancer cells

Big data helps determine better research models to fight the spread of breast cancer

Big data helps determine better research models to fight the spread of breast cancer

MDI Biological Laboratory receives $30,000 to support course in organoid technology

MDI Biological Laboratory receives $30,000 to support course in organoid technology

Six plants native to Southeast Asia show cancer-fighting properties

Six plants native to Southeast Asia show cancer-fighting properties

New drug targeting genetic weakness could become first treatment for childhood brain cancer

New drug targeting genetic weakness could become first treatment for childhood brain cancer

Aptamer Therapeutics collaborates with Cancer Research UK for drug development program

Aptamer Therapeutics collaborates with Cancer Research UK for drug development program

New HKBU method could lead to the production of higher quality medicinal drugs

New HKBU method could lead to the production of higher quality medicinal drugs

New chemical synthesis strategy leads to identification of novel, simpler derivatives

New chemical synthesis strategy leads to identification of novel, simpler derivatives

Uncovering the Structure of HIV Integrase to Inform Drug Discovery

Uncovering the Structure of HIV Integrase to Inform Drug Discovery

Scientists identify 104 high-risk genes for schizophrenia

Scientists identify 104 high-risk genes for schizophrenia

New discovery transforms conventional microfluidics into open-space microfluidics

New discovery transforms conventional microfluidics into open-space microfluidics

Scientists enter research collaboration to find a cure for cancer

Scientists enter research collaboration to find a cure for cancer

Researchers create new small molecules that may combat equine encephalitis viruses

Researchers create new small molecules that may combat equine encephalitis viruses

Using slime mold to produce accessible biosensors

Using slime mold to produce accessible biosensors

Biomolecular researcher provides comprehensive profile of B cells in rheumatoid arthritis

Biomolecular researcher provides comprehensive profile of B cells in rheumatoid arthritis

Study describes vulnerability shared by large subset of cancer cell lines

Study describes vulnerability shared by large subset of cancer cell lines