Drug Discovery News and Research

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The drug discovery process begins with recognizing a disease or clinical condition in which there is a lack of adequate medical treatment. Once a potential drug has been identified, pre-clinical research can begin. This process includes several stages; the first of which involves identifying and validating the prospective drug’s target through assay development, high throughput screening, hit identification and finally, lead optimization. Once the pre-clinical process is complete, the newly synthesized drug candidate is selected for future clinical development.

CLYD gene serves as crucial negative regulator in pulmonary fibrosis

An international team of researchers led by Georgia State University scientists have found a key component in the pathological process of pulmonary fibrosis, a fatal disease for which there is currently no cure.

11 Apr 2012

Mayo Clinic introduces Breast Cancer Genome Guided Therapy Study

The Breast Cancer Genome Guided Therapy Study (BEAUTY Project) will help physicians tailor chemotherapy to breast cancer patients based on their individual genomes and the genomes of their tumors.

10 Apr 2012

Chemotherapy based on individual genomes and genomes of tumors

The Breast Cancer Genome Guided Therapy Study (BEAUTY Project) will help physicians tailor chemotherapy to breast cancer patients based on their individual genomes and the genomes of their tumors.

9 Apr 2012

Label-Free Technologies Conference to be held in Amsterdam

Elsevier, a world-leading provider of scientific, technical and medical information products and services, announces the Label-Free Technologies Conference to be held in Amsterdam, the Netherlands, 1-3 November 2012.

6 Apr 2012

BioScale presents data on phospho-protein analysis of MAP kinase pathway activation state at 103rd AACR

BioScale, Inc. a life science company that develops ultrasensitive protein analysis technology, presented findings of recently completed research studies on phospho-protein analysis of the activation state of the MAP kinase pathway at the 103rd Annual Meeting of the American Association for Cancer Research (AACR), held at McCormick Place in Chicago, Illinois, March 31 - April 4, 2012.

3 Apr 2012

Organovo 2011 total revenues increase 61% to $968,513

Organovo Holdings, Inc., a three-dimensional biology company focused on delivering breakthrough 3D bioprinting technology, today reported the financial results for the year ended December 31, 2011.

3 Apr 2012

Cancer cells grow and proliferate more robustly when exposed to human cells

New research from the Technion-Israel Institute of Technology Rappaport Faculty of Medicine and Research Institute and the Rambam Medical Center may lead to the development of new methods for controlling the growth of cancer, and perhaps lead to treatments that will transform cancer from a lethal disease to a chronic, manageable one, similar to AIDS.

30 Mar 2012

Scientists identify potential drug target for mixed lineage leukaemia

Cancer Research UK scientists have discovered a promising new approach to treat a type of myeloid leukaemia - a cancer with limited treatment options and relatively poor survival, according to research published in Cancer Cell today.

30 Mar 2012

CRT, EIF create £50M Cancer Research Technology Pioneer Fund

Cancer Research Technology, (CRT) Cancer Research UK's commercial arm, and the European Investment Fund (EIF) have joined together to create a £50M investment fund to bridge the funding gap in the UK between cancer drug discovery and early development.

29 Mar 2012

BioSeek, Merck Serono sign new BioMAP collaboration agreement

BioSeek, LLC, a subsidiary of Asterand plc, a pioneer in the application of predictive human biology to drug discovery, announced today that it has signed a new, three-year collaboration agreement with Merck Serono, a division of Merck KGaA, Darmstadt, Germany.

29 Mar 2012

Pernix fourth quarter net revenues increase 74% to $21.4 million

Pernix Therapeutics Holdings, Inc., a specialty pharmaceutical company, today announced financial results for the quarter and year ended December 31, 2011.

29 Mar 2012

Therapy Finder - Colorectal Cancer app now available for patients

No one wants to hear the words, "you have colon cancer." For patients diagnosed with an advanced form of the disease, these words can be particularly devastating. The five-year survival rate can be a little as 6 percent. The top-of-mind question becomes, "Which treatment or clinical trial will work for me?"

28 Mar 2012

Top-line results from two Targacept TC-6987 Phase 2 studies on asthma, type 2 diabetes

Targacept, Inc., a clinical-stage biopharmaceutical company developing novel NNR Therapeutics, today announced top-line results from two separate exploratory Phase 2 studies of its product candidate TC-6987 conducted in the United States, one in asthma and one in type 2 diabetes.

28 Mar 2012

Researchers use skin cells from MND patient to create motor neurones

A breakthrough using cutting-edge stem cell research could speed up the discovery of new treatments for motor neurone disease (MND).

27 Mar 2012

BioLife fourth quarter total revenue increases 41% to $809,564

BioLife Solutions, Inc., a leading developer, manufacturer and marketer of proprietary clinical grade hypothermic storage and cryopreservation freeze media for cells and tissues, and contract aseptic media manufacturer, today announced record revenue for the fourth quarter and full year 2011, and for the first time, provided initial guidance on management's outlook for the full year 2012.

26 Mar 2012

UI receives three grants to hasten discovery of new TB therapeutics

Forty-five years. That's how long it's been since the last drug - rifampin - hit the market to treat tuberculosis, an infection that affects nearly one third of the world's population and causes 1.8 million deaths annually. The University of Illinois at Chicago College of Pharmacy has received three new federally-funded grants to hasten the discovery of new therapeutic treatments.

23 Mar 2012

Verapamil drug may reverse diabetes-related death of pancreatic beta cells

A common high-blood-pressure medication appears to reverse the diabetes-related death of pancreatic beta cells, according to a University of Alabama at Birmingham study published today in the journal Diabetes.

23 Mar 2012

Study shows gender gap in medication management

Women use more prescription drugs than men; yet they are not prescribed proper amounts. In a new study presented at Women's Health 2012: The 20th Annual Congress by Medco Health Solutions, Inc. and the Society for Women's Health Research (SWHR) women are prescribed more drugs than men, have poorer adherence rates to using the drugs than men, and, perhaps most surprisingly, lag behind men in receiving the appropriate drugs for their documented diseases.

22 Mar 2012

n3D releases new 24-well Bio-Assembler

Only days after Rainbow BioSciences closed a deal to acquire an equity interest in Nano3D Biosciences, n3D announced the release of its groundbreaking new 24-well Bio-Assembler.

20 Mar 2012

Chemists produce first high resolution structure of HCV viral RNA-inhibitor complex

Chemists at the University of California, San Diego have produced the first high resolution structure of a molecule that when attached to the genetic material of the hepatitis C virus prevents it from reproducing.

20 Mar 2012