Drug Discovery News and Research

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The drug discovery process begins with recognizing a disease or clinical condition in which there is a lack of adequate medical treatment. Once a potential drug has been identified, pre-clinical research can begin. This process includes several stages; the first of which involves identifying and validating the prospective drug’s target through assay development, high throughput screening, hit identification and finally, lead optimization. Once the pre-clinical process is complete, the newly synthesized drug candidate is selected for future clinical development.
Physicist creates technology that may enhance pharma industry's early drug discovery capabilities

Physicist creates technology that may enhance pharma industry's early drug discovery capabilities

Targacept initiates TC-6987 Phase 2 study in patients with asthma, Type 2 diabetes

Targacept initiates TC-6987 Phase 2 study in patients with asthma, Type 2 diabetes

Evotec signs definitive agreement to acquire all shares in Kinaxo

Evotec signs definitive agreement to acquire all shares in Kinaxo

Protect Pharma completes sale of two patents and patents-applications to Grunenthal

Protect Pharma completes sale of two patents and patents-applications to Grunenthal

Single molecule imaging movies of living cell membranes clarify enigma surrounding receptor molecule behaviors

Single molecule imaging movies of living cell membranes clarify enigma surrounding receptor molecule behaviors

Ansaris receives milestone payment for identification of kinase-related compound for cancer, autoimmune diseases

Ansaris receives milestone payment for identification of kinase-related compound for cancer, autoimmune diseases

Elan 2010 total revenue increases 5% to $1,169.7 million

Elan 2010 total revenue increases 5% to $1,169.7 million

Researchers develop new method for drug discovery using math to combat HIV, other diseases

Researchers develop new method for drug discovery using math to combat HIV, other diseases

Tufts announces public launch of Institute for Biomedical Partnerships, HUB website

Tufts announces public launch of Institute for Biomedical Partnerships, HUB website

AMRI fourth quarter total revenue increases 12% to $48.6 million

AMRI fourth quarter total revenue increases 12% to $48.6 million

JDRF, Eli Lilly sign agreement to fund type 1 diabetes research for re-generative medicine

JDRF, Eli Lilly sign agreement to fund type 1 diabetes research for re-generative medicine

Isis commences ISIS-FXIRx Phase 1 study for treatment of clotting disorders

Isis commences ISIS-FXIRx Phase 1 study for treatment of clotting disorders

Five young scientists receive Damon Runyon-Rachleff Innovation Award for cancer research

Five young scientists receive Damon Runyon-Rachleff Innovation Award for cancer research

Aphios enters subcontract with SAIC-Frederick to develop phospholipid nanoencapsulated camptothecin

Aphios enters subcontract with SAIC-Frederick to develop phospholipid nanoencapsulated camptothecin

First blood-based diagnostic test for LAM

First blood-based diagnostic test for LAM

FDA, Optivia collaborate to examine effect of dietary supplements in drug-induced liver injury

FDA, Optivia collaborate to examine effect of dietary supplements in drug-induced liver injury

Venture philanthropist invests $3.5 million to thwart Alzheimer's disease

Venture philanthropist invests $3.5 million to thwart Alzheimer's disease

ALS Biopharma receives ADDF grant to develop therapeutics against Alzheimer's disease

ALS Biopharma receives ADDF grant to develop therapeutics against Alzheimer's disease

H3 Biomedicine introduces cancer research and development operations in Cambridge

H3 Biomedicine introduces cancer research and development operations in Cambridge

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