Drug Discovery News and Research

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The drug discovery process begins with recognizing a disease or clinical condition in which there is a lack of adequate medical treatment. Once a potential drug has been identified, pre-clinical research can begin. This process includes several stages; the first of which involves identifying and validating the prospective drug’s target through assay development, high throughput screening, hit identification and finally, lead optimization. Once the pre-clinical process is complete, the newly synthesized drug candidate is selected for future clinical development.
Brain chemical anandamide work as antidepressant

Brain chemical anandamide work as antidepressant

Herb rosemary fights free radical damage in the brain

Herb rosemary fights free radical damage in the brain

Discovery of two genes linked to a disabling form of arthritis called ankylosing spondylitis

Discovery of two genes linked to a disabling form of arthritis called ankylosing spondylitis

Childhood epilepsy research offers new hope for seizure control

Childhood epilepsy research offers new hope for seizure control

Sugars, not proteins make bones tough

Sugars, not proteins make bones tough

Wyeth Pharmaceuticals to acquire Haptogen

Wyeth Pharmaceuticals to acquire Haptogen

40,000 computers used to tackle bird flu in search for new anti-viral drug discoveries

40,000 computers used to tackle bird flu in search for new anti-viral drug discoveries

Isis Pharmaceuticals awarded $1.5 million NIH grant to improve RNAi-based therapeutics

Isis Pharmaceuticals awarded $1.5 million NIH grant to improve RNAi-based therapeutics

Loss of TDP-43 gene found to be related to age-related neurological disorders

Loss of TDP-43 gene found to be related to age-related neurological disorders

Adnexus Therapeutics to become a subsidiary of Bristol-Myers Squibb

Adnexus Therapeutics to become a subsidiary of Bristol-Myers Squibb

Cell growth technology promises more successful drug development

Cell growth technology promises more successful drug development

Gates Foundation digs down deep for TB

Gates Foundation digs down deep for TB

Spinal Muscular Atrophy Foundation and BG Medicine collaborate

Spinal Muscular Atrophy Foundation and BG Medicine collaborate

GlaxoSmithKline to pursue novel antibacterial research program for DOD

GlaxoSmithKline to pursue novel antibacterial research program for DOD

New Rensselaer tools speed stem cell research

New Rensselaer tools speed stem cell research

Innovative liquid crystal technology offers promise of new drugs

Innovative liquid crystal technology offers promise of new drugs

Hamburg to become Europe's hub of drug discovery

Hamburg to become Europe's hub of drug discovery

Animal model for dengue research

Animal model for dengue research

Cancer Research Technology begins critical role in new Australian cancer research venture

Cancer Research Technology begins critical role in new Australian cancer research venture

Cause of major subtype of glaucoma discovered

Cause of major subtype of glaucoma discovered