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Study reveals shocking rise in opioid deaths among Canadian youth

Premature deaths related to opioids doubled between 2019 and 2021 across Canada, with more than 1 in 4 deaths among young adults aged 20–39 years attributable to opioids, according to new research published in CMAJ.

15 Apr 2024

Swap funds or add services? Use of opioid settlement cash sparks strong disagreements

State and local governments are receiving billions of dollars in opioid settlements to address the drug crisis that has ravaged America for decades.

15 Apr 2024

Study unlocks genetic secrets in APOEε4 carriers that could defend against Alzheimer's

Researchers utilized whole-genome sequencing and pathway analysis to uncover protective genetic variations against Alzheimer's disease in APOEε4 carriers, revealing a crucial role for extracellular matrix-related genes in mitigating the disease's progression.

15 Apr 2024

Esketamine after childbirth cuts risk of postnatal depression by three-quarters

Low-dose esketamine administered post-labor significantly reduced depressive symptoms in women with prenatal depression within 42 days, despite an increase in short-lived neuropsychiatric side effects.

14 Apr 2024

Study reveals high prevalence of menstrual migraines in U.S. women

A third of the nearly 20 million women who participated in a national health survey report migraines during menstruation, and of them, 11.8 million, or 52.5%, were premenopausal.

13 Apr 2024

U-M study reveals potential pathway to reverse lung fibrosis

The most common type of lung fibrosis -; scarring of the lungs -- is idiopathic, meaning of unknown cause.

13 Apr 2024

Deciphering the molecular interactions of opioid receptors: Implications for drug design

Drugs that target opioid receptors sometimes have severe side effects. Thousands of people around the world die every day from overdoses involving opioids such as fentanyl.

13 Apr 2024

Breakthrough study reveals melanoma's resistance tactics to targeted therapy

Melanoma is the deadliest form of skin cancer. With global incidence rates rising, new, more effective treatments are necessary to alleviate the health burden of the disease. Important advances in recent years include doctors using genetic tests to look for specific mutations they can target for more personalised, effective treatment.

13 Apr 2024

Soft tumor environments prime cancer cells for survival during metastasis

Researchers have discovered how the mechanical properties of tumors can prime cancer cells to better survive their spread to other organs.

13 Apr 2024

Insilico Medicine's AI-driven approach yields promising PTPN2/N1 inhibitor for cancer immunotherapy

In recent years, cancer immunotherapy, exemplified by PD-1 and its ligand PD-L1 blockade, has made remarkable advances.

13 Apr 2024

Women predominantly treated for anxiety and depression at psychiatric outpatient clinics

More than 75% of the patients treated at the psychiatric outpatient clinic of Hospital de Base in São José do Rio Preto, São Paulo state (Brazil), are women with a mean age of 45 and suffering from sadness, anxiety and irritability, according to a study reported in the journal Frontiers in Psychiatry.

13 Apr 2024

Restoring insulin sensitivity without TZD side effects

Thiazolidinediones (TZDs) are a class of drug that can be used to treat type 2 diabetes by reversing insulin resistance, one of the main hallmarks of the disease.

13 Apr 2024

NCCN 2024 Annual Conference focuses on practical applications for improving cancer care

The National Comprehensive Cancer Network (NCCN)-;an alliance of leading cancer centers-;hosted more than 1,700 oncology professionals during the NCCN 2024 Annual Conference on April 5-7.

13 Apr 2024

Innovative cancer treatment approach yields promising results in pediatric patients

Researchers have developed a functional precision medicine approach that targets cancer by combining genetic testing with a new way to test individual drugs on tumor samples.

12 Apr 2024

Unveiling the key role of RNA modification in HIV-1 survival and replication

A chemical modification in the HIV-1 RNA genome whose function has been a matter of scientific debate is now confirmed to be key to the virus's ability to survive and thrive after infecting host cells, a new study has found.

12 Apr 2024

Study reveals how DNA gyrase resolves DNA entanglements

Picture in your mind a traditional "landline" telephone with a coiled cord connecting the handset to the phone.

12 Apr 2024

Nanopore sequencing unveils novel telomere length patterns

We depend on our cells being able to divide and multiply, whether it's to replace sunburnt skin or replenish our blood supply and recover from injury.

12 Apr 2024

Robotic lung transplantation: A paradigm shift in surgical approach

While debating the pros and cons of robotically assisted lung transplantation, Albert Jauregui, MD, PhD told attendees at the Annual Meeting and Scientific Sessions of the International Society for Heart and Lung Transplantation (ISHLT), today in Prague that the time for robotic surgery is now.

12 Apr 2024

Rising antibiotic resistance prompts shift to ecological research strategies in infection control

The need to enhance research on the interactions between bacterial pathogens and commensals within human microbiomes.

12 Apr 2024

Geraniol alleviates cognitive decline in D-galactose-induced aging mice

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 6, entitled, "Geraniol attenuates oxidative stress and neuroinflammation-mediated cognitive impairment in D galactose-induced mouse aging model."

12 Apr 2024

Drugs News and Research

Study reveals shocking rise in opioid deaths among Canadian youth

Swap funds or add services? Use of opioid settlement cash sparks strong disagreements

Study unlocks genetic secrets in APOEε4 carriers that could defend against Alzheimer's

Esketamine after childbirth cuts risk of postnatal depression by three-quarters

Study reveals high prevalence of menstrual migraines in U.S. women

U-M study reveals potential pathway to reverse lung fibrosis

Deciphering the molecular interactions of opioid receptors: Implications for drug design

Breakthrough study reveals melanoma's resistance tactics to targeted therapy

Soft tumor environments prime cancer cells for survival during metastasis

Insilico Medicine's AI-driven approach yields promising PTPN2/N1 inhibitor for cancer immunotherapy

Women predominantly treated for anxiety and depression at psychiatric outpatient clinics

Restoring insulin sensitivity without TZD side effects

NCCN 2024 Annual Conference focuses on practical applications for improving cancer care

Innovative cancer treatment approach yields promising results in pediatric patients

Unveiling the key role of RNA modification in HIV-1 survival and replication

Study reveals how DNA gyrase resolves DNA entanglements

Nanopore sequencing unveils novel telomere length patterns

Robotic lung transplantation: A paradigm shift in surgical approach

Rising antibiotic resistance prompts shift to ecological research strategies in infection control

Geraniol alleviates cognitive decline in D-galactose-induced aging mice

Drug Discovery - Second Edition eBook

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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