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Matrix metalloproteinase-assisted triggered release of liposomal contents

Cancer cells display a variety of proteins on their outer membranes that are not present on the surface of normal cells.

16 Jan 2008

New technique could dramatically lower costs of DNA sequencing

Using computer simulations, researchers at the University of Illinois have demonstrated a strategy for sequencing DNA by driving the molecule back and forth through a nanopore capacitor in a semiconductor chip.

16 Jan 2008

Viroporins, membrane-permeabilizing proteins of the poliomyelitis virus

A research team from the Universidad Autonoma de Madrid directed by Professor Luís Carrasco has published new discoveries concerning the membrane permeabilizing proteins of the polio virus.

16 Jan 2008

Bisphosphonates - osteoporosis drugs triple risk of bone necrosis

A University of British Columbia and Vancouver Coastal Health Research Institute study has found that a popular class of osteoporosis drugs nearly triples the risk of developing bone necrosis, a condition that can lead to disfigurement and incapacitating pain.

16 Jan 2008

New research may shed light on how proteins interact with drugs and other small molecules

Proteins, the biological molecules involved in virtually every action of every organism, may themselves move in surprising ways, according to a recent study from the U.S. Department of Energy's Argonne National Laboratory that may shed new light on how proteins interact with drugs and other small molecules.

16 Jan 2008

Molecules might identify high-risk acute-leukemia patients

New research suggests that certain small molecules used by cells to control the proteins they make might also help doctors identify adult acute-leukemia patients who are likely to respond poorly to therapy.

16 Jan 2008

Lack of training in prescribing medicines for children

Current training and assessment for curbing common pitfalls in medicines prescribing for children is inadequate, suggests research published ahead of print in Archives of Disease in Childhood.

16 Jan 2008

Hormonal nutritional supplements might speed prostate cancer progression

Hormonal components in over-the-counter dietary supplements may promote the progression of prostate cancer and decrease the effectiveness of anti-cancer drugs, researchers at UT Southwestern Medical Center have discovered.

16 Jan 2008

Trust between doctors and patients is culprit in efforts to cross racial divide in medical research

More than three decades after the shutdown of the notorious Tuskegee study, a team of Johns Hopkins physicians has found that Tuskegee's legacy of blacks' mistrust of physicians and deep-seated fear of harm from medical research persists and is largely to blame for keeping much-needed African Americans from taking part in clinical trials.

16 Jan 2008

FDA says meat from cloned animals is safe but not everyone agrees

The Food and Drug Administration (FDA) in the United States has announced that meat from cloned animals is safe for human consumption.

16 Jan 2008

Probiotic drinks work - but who knows how or why?

New research from Imperial College London and the Nestlé Research Center, Lausanne, Switzerland, says that probiotic drinks and yoghurts help the gut but it is unclear how or why.

16 Jan 2008

OIG report confirms dangerously thin margins for community pharmacy

The Office of the Inspector General of the Department of Health and Human Services released a "Review of the Relationship Between Medicare Part D Payments to Local, Community Pharmacies and the Pharmacies' Drug Acquisition Costs."

15 Jan 2008

Hormonal components in over-the-counter dietary supplements might promote prostate cancer progression

15 Jan 2008

Sickle cell disease pain study

A new prospective study of pain in adults with sickle cell disease finds that daily pain is far more prevalent and severe than previous large studies have indicated.

15 Jan 2008

Selective restraints and reduced medication could reduce nursing home falls

Selectively restraining elderly residents and giving them fewer sleeping pills could significantly reduce falls, according to a survey of 21 nursing home units published in the January issue of Journal of Clinical Nursing.

15 Jan 2008

Potential new treatment for inflammatory bowel disease

Irish scientists have discovered a new potential therapeutic approach to Inflammatory Bowel Disease (IBD), a chronic debilitating disease involving inflammation of the intestine which affects more than 15,000 people in Ireland and millions of people worldwide.

15 Jan 2008

Researchers find new way to block destructive rush of immune cells

Researchers have found a way to selectively block the ability of white blood cells to "crawl" toward the sites of injury and infection when such mobility drives disease, according to a study published today in The Journal of Experimental Medicine.

15 Jan 2008

Psychotherapies are under-regulated in the UK, experts say

Psychotherapies such as cognitive behaviour therapy (CBT) are under-regulated in the UK and should be subject to the same standards of evidence as drugs, assert two experts in psychological medicine writing in the Journal of Psychopharmacology (January issue published by SAGE).

15 Jan 2008

Mouse model shows potential efficacy of HIV prevention strategy

A new kind of laboratory mouse can be used to test the efficacy of much-needed methods to prevent transmission of HIV, the virus that causes AIDS, according to research by J. Victor Garcia and colleagues at the University of Texas Southwestern Medical Center in Dallas.

15 Jan 2008