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New target for Hepatocellular carcinoma therapy

Hepatocellular carcinoma (HCC) is a major health problem worldwide. Currently, the only chance for obtaining a cure in patients with HCC is by either a surgical resection or liver transplantation.

25 Oct 2007

Positive results for novel anti-cancer drug ECO-4601

Researchers report positive results from a Phase I/II clinical trial of a novel anti-cancer drug which offers two modes of action.

24 Oct 2007

New type of biodegradable nanoparticle for drug delivery

The spherical structures can encapsulate various fat-soluble medicines, which makes it easier to target tumour tissue. These nanoballs are highly promising carriers for the controlled release of anticancer drugs. Rijcken recently gained her doctorate for this research from Utrecht University.

24 Oct 2007

HIV combination antiretroviral drug therapy key to saving the lives of African children

Letting nurses and other trained health care workers deliver that therapy and monitor patients, especially when doctors are in short supply, is just as important to saving lives, according to a new study by the University of Alabama at Birmingham (UAB).

24 Oct 2007

Potential new ways to treat ulcers

The alarming truth is more than 14.5 million people suffer from ulcers worldwide due to factors such as stress and the use of non-steroidal anti-inflammatory drugs (NSAIDS).

24 Oct 2007

Most parents ignorant to teenager's substance use

New research results from the University at Buffalo's Research Institute on Addictions (RIA) suggest that most parents are aware of and accurately evaluate the extent of their teenager's cigarette smoking, marijuana use, drinking and overall substance use.

24 Oct 2007

Carbamazepine and valproate may cause sexual disorders

The use of antiepileptic drugs (AEDs) can lead to decreased fertility and increased incidence of reproductive endocrine disorders in both men and women.

24 Oct 2007

New understanding of vagus nerve's role in regulating inflammation

It used to be dogma that the brain was shut away from the actions of the immune system, shielded from the outside forces of nature.

24 Oct 2007

Combination targets offer new hope in fight against cancer

While some targeted therapies - drugs developed to attack specific molecules in the critical chemical pathways occurring within cancer cells - work well by themselves, increasingly researchers are finding that they work better when teamed with other targeted and conventional therapies.

24 Oct 2007

Alcoholism in the family linked to greater sweet preferences among women

More than 250 million women worldwide smoke tobacco. Compared to men, women have a greater risk of smoking-related diseases, and also have more difficulty quitting. A new study, the first of its kind, has found that cigarette smoking and having a family history of alcoholism have different effects on sweet-taste perception and food cravings.

24 Oct 2007

Synthetic form of THC is an effective anti-depressant at low doses

A new neurobiological study has found that a synthetic form of THC, the active ingredient in cannabis, is an effective anti-depressant at low doses.

24 Oct 2007

Orexigen presents findings on obesity drug candidates

Orexigen Therapeutics, Inc., a biopharmaceutical company focused on the treatment of central nervous system (CNS) disorders including obesity, has presented the results of a preclinical study that further supports the Company's understanding of an aspect of the mechanism of action of Contrave, one of its two late-stage obesity drug candidates.

24 Oct 2007

Exercise and counseling could ease cancer-related fatigue

Cancer patients suffering from symptoms of fatigue might find some relief through regular exercise and psychological counseling to deal with stress, according to a new review.

24 Oct 2007

Advances in drug screening

With the discovery of suitable molecular targets - cellular molecules along pathways crucial for sustaining the life of cancer cells - comes the perplexing dilemma of where to find the next therapeutics that will bind to and disable those targets.

23 Oct 2007

Anti-tuberculosis program in South Africa may have inadvertently helped create new strain of XDR TB

In a new study published in the December 1 issue of Clinical Infectious Diseases, currently available online, researchers tracked the developing drug resistance of one particular strain of Mycobacterium tuberculosis over 12 years.

22 Oct 2007

Gold-like drugs to treat arthritis

Scientists at Duke University Medical Center may have solved the mystery surrounding the healing properties of gold - a discovery they say may renew interest in gold salts as a treatment for rheumatoid arthritis and other inflammatory diseases.

22 Oct 2007

Heparanase shows potential as cancer drug

Laboratory experiments have previously shown that cancer cells overproduce an enzyme, heparanase, which splits the body's own polysaccharide heparan sulfate into shorter fragments.

22 Oct 2007

Hispanics and African Americans are less likely to use commercial weight loss programs

A new analysis of a landmark weight loss survey suggests that Hispanics and African Americans are more likely than whites to use unproven dietary supplements for weight loss.

22 Oct 2007

Microbix Biosystems granted U.S. patent for its influenza vaccine

Microbix Biosystems Inc. has been granted a patent by the U.S. Patent Office for its technology - VIRUSMAX - which enables vaccine manufacturers to double the amount of influenza vaccine they produce each year.

22 Oct 2007

High-risk individuals less likely to follow through on HIV testing plans

One-fourth of individuals at high risk for contracting HIV report planning to be tested for the virus in the next year, but fewer appear to follow through on that intention than individuals who are at lower risk, according to a report in the October 22 issue of Archives of Internal Medicine.

22 Oct 2007