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Profound alterations in the brain mechanisms that regulate motivated behavior with addiction

Rats that have a strong craving for cocaine have a different biochemical response to the drug than their less-addicted counterparts, researchers at UT Southwestern Medical Center have found.

15 Mar 2006

Impact of a scientific presentation on community treatment patterns for primary breast cancer

The oral presentation of data from a single study at a national scientific conference can have an important impact on patient treatment, even before study publication or Food and Drug Administration (FDA) approval

15 Mar 2006

Hospitalized schizophrenics more likely to have complications

A Johns Hopkins study of more than 1,700 patients with schizophrenia hospitalized for medical or surgical care unrelated to their mental disorder shows they are at least twice as likely as similar patients without schizophrenia to suffer dangerous and expensive adverse events.

15 Mar 2006

The transcription factor MEF/ELF4 regulates the quiescence of primitive hematopoietic cells

Scientists have uncovered new information about what orchestrates the complex balance between blood stem cells and mature blood cells, a relationship that is often disrupted in leukemia.

15 Mar 2006

Scientists gain better understanding of the behavior of leukemic cells

Scientists have uncovered new information about what orchestrates the complex balance between blood stem cells and mature blood cells, a relationship that is often disrupted in leukemia.

15 Mar 2006

Driving times and distances to hospitals with percutaneous coronary intervention in the United States

Diverting ambulances with patients suffering a heart to a hospital providing emergency angioplasty rather than a closer hospital with no ability to provide this specialized care, may be feasible for the majority of Americans

15 Mar 2006

Man-made chemical compound targets and kills tumor cells

A man-made chemical compound called ARC causes tumor cells to die but leaves normal cells unharmed, researchers at the University of Illinois at Chicago report in a study highlighted in the March 15 issue of Cancer Research.

15 Mar 2006

Cells have a natural defense against HIV

Scientists here have discovered a previously unknown mechanism that cells use to fight off the human immunodeficiency virus (HIV), the cause of AIDS.

14 Mar 2006

Decitabine improves myelodysplastic syndrome treatment

A potent member of a new class of drugs increases survival in some patients with myelodysplastic syndrome (MDS), and may become the new standard of therapy for this group of pre-cancer disorders

14 Mar 2006

Yale researchers identifiy a gene that protects the body against kidney stones

The research identifies a transporter, encoded by the gene, as a potential target for drugs to boost oxalate secretion in the gut and help prevent kidney stones, said Peter Aronson, M.D., professor of internal medicine and physiology and senior author of the research.

14 Mar 2006

Antiretroviral therapy (ART) drugs unlikely to stop HIV spread

Researchers believe antiretroviral therapy (ART) will not be effective in stopping HIV epidemics even if it is made universally available in poorer countries, and that widespread use could even lead to an increase in the numbers infected with HIV.

14 Mar 2006

Intensive cholesterol lowering with a statins can partially reverse the buildup of plaque in the coronary arteries

A study presented at the American College of Cardiology's 55th Annual Scientific Session demonstrates, for the first time, that very intensive cholesterol lowering with a statin drug can regress (partially reverse) the buildup of plaque in the coronary arteries.

14 Mar 2006