Ductal Carcinoma in Situ (DCIS) News and Research

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Ductal Carcinoma in Situ (DCIS) is a condition where the cells lining the milk ducts (the channels in the breast that carry milk to the nipple) are cancerous, but stay contained within the ducts without growing through into the surrounding breast tissue. DCIS may affect just one area of the breast, but can be more widespread and affect different areas at the same time. Sometimes DCIS may be described as pre-cancerous, pre-invasive, non-invasive, or intraductal cancer.

New gene classifier can predict the risk of cancer cells recurring or progressing

A team of researchers mapping a molecular atlas for ductal carcinoma in situ (DCIS) has made a major advance toward distinguishing whether the early pre-cancers in the breast will develop into invasive cancers or remain stable.

20 Nov 2022

Celebrating 10 Years of Global Research with Breast Cancer Now Tissue Bank

Breast Cancer Now Tissue Bank have just celebrated 10 years of groundbreaking breast cancer research. We spoke to Professor Louise Jones to find out more about this achievement!

22 Aug 2022

Diagnostic mammograms' accuracy may differ across racial and ethnic groups

The accuracy of diagnostic mammograms differed across racial and ethnic groups, with variation in several measures of diagnostic performance.

17 Jun 2022

Insight into the Breast Cancer Landscape with Breast Cancer Now

In this interview, we speak with Dr. Simon Vincent, Director of Research, Support, and Influencing at Breast Cancer Now, about the current landscape of breast cancer.

12 Apr 2022

Many women experience confusion and distress after ductal carcinoma in situ diagnoses

Each year in the United States, nearly 50,000 women are diagnosed with ductal carcinoma in situ (DCIS), a non-invasive breast condition that cannot spread.

22 Feb 2022

Cavity shave margin resection reduces the rate of positive margins in patients with DCIS

According to the American Cancer Society, a noninvasive breast cancer called ductal carcinoma in situ (DCIS) accounts for approximately one of every four new breast cancer cases in the United States.

5 Apr 2021

Researchers successfully perform terahertz imaging of early-stage breast cancer without staining

A team of researchers at Osaka University, in collaboration with the University of Bordeaux and the Bergonié Institute in France, has succeeded in terahertz imaging of early-stage breast cancer less than 0.5 mm without staining, which is difficult to identify even by pathological diagnosis.

21 Oct 2020

Study: Radiotherapy and surgery offer better protection in treating abnormal breast tissue

A major study of women with ductal carcinoma in situ (DCIS) - a breast condition that can become invasive cancer - has shown that surgery to remove the tissue followed by radiotherapy offers better protection compared to surgery alone.

5 Oct 2020

New findings clarify the long-term risks for women with DCIS

5 Oct 2020

New approach uses AI to identify which early stage breast cancers will spread

About 1 in 5 new breast cancers are caught at their earliest stages, before they've spread from milk ducts into the surrounding breast tissue.

25 Sep 2020

DCIS surgical delays do not impact overall survival, shows study

Beginning in March, as COVID-19 cases surged in various states in the U.S., the COVID-19 Pandemic Breast Cancer Consortium released recommendations that operations for ductal carcinoma in situ (DCIS) be deferred due to the pandemic.

7 Aug 2020

Surgical delay does not lower overall survival of women with early-stage breast cancer

A new breast cancer study brings reassuring findings for women with early-stage breast cancer who were forced to delay their cancer operations because of the Coronavirus Disease 2019 (COVID-19) pandemic.

6 Aug 2020

Monoclonal antibody therapy achieves modest reduction in recurrence for patients with HER2-positive DCIS

The addition of the monoclonal antibody therapy Trastuzumab to radiotherapy did not reach the protocol objective of a 36% reduction in the ipsilateral breast tumor recurrence rate for women with HER2-positive ductal carcinoma in situ (DCIS) on the NRG Oncology clinical trial NSABP B-43.

29 May 2020

High-resolution imaging with elastography could accurately spot breast cancer in surgical margins

A high-resolution, three-dimensional imaging technique, when combined with quantitative measurement of tissue elasticity, could accurately detect cancer within the resected margins of surgical specimens taken from patients undergoing breast-conserving surgery.

15 Apr 2020

Radiation therapy alone found to be cost-effective for treatment of DCIS

Ductal carcinoma in-situ (DCIS) accounts for one-fifth of breast cancer cases in the United States, according to the American Cancer Society.

11 Dec 2019

New research could help better understand progress of breast cancer

New research at Case Western Reserve University could help better determine which patients diagnosed with the pre-malignant breast cancer commonly as stage 0 are likely to progress to invasive breast cancer and therefore might benefit from additional therapy over and above surgery alone.

29 Oct 2019

Older women with DCIS gain no benefit from sentinel lymph node biopsy

Older women with a very early, non-invasive breast cancer known as ductal carcinoma in situ (DCIS) gain no long-term benefit from undergoing a sentinel lymph node biopsy to see if the cancer has spread, new research by the Yale School of Public Health has found.

24 Oct 2019

Six factors associated with invasive breast cancer recurrence after DCIS diagnosis

Six factors were associated with invasive recurrence of breast cancer after a diagnosis of ductal carcinoma in situ (DCIS), according to data from a meta-analysis.

25 Apr 2019

Radiation therapy can lower risk of breast cancer recurrence in patients with ‘good risk’ DCIS

A subset of patients with low-risk breast cancer is highly unlikely to see cancer return following breast conservation surgery but can lower that risk even further with radiation therapy, finds a new long-term clinical trial report.

30 Oct 2018

Study identifies molecular switch that controls fate of milk-producing breast cells

A research team, led by investigators from Georgetown Lombardi Comprehensive Cancer Center, details how a natural and dramatic process -- changes in mammary glands to accommodate breastfeeding -- uses a molecular process believed to contribute to survival of pre-malignant breast cells.

15 Oct 2018