Ductal Carcinoma in Situ (DCIS) News and Research

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Ductal Carcinoma in Situ (DCIS) is a condition where the cells lining the milk ducts (the channels in the breast that carry milk to the nipple) are cancerous, but stay contained within the ducts without growing through into the surrounding breast tissue. DCIS may affect just one area of the breast, but can be more widespread and affect different areas at the same time. Sometimes DCIS may be described as pre-cancerous, pre-invasive, non-invasive, or intraductal cancer.

Breast cancer cells have to learn to walk before they can run

Early-stage breast cancer that has not yet invaded the surrounding tissues may already contain highly motile cells, bringing the tumor one step closer to metastasis, report researchers at the Salk Institute for Biological Studies.

2 Jan 2008

Early results show promise in reducing side effects from anastrozole

A common osteoporosis drug can shield women against the loss of bone mineral density - a side effect of the drug anastrozole which is taken to prevent breast cancer in the IBIS-2 study - according to new data presented at the San Antonio Breast Cancer Symposium.

14 Dec 2007

Cell response to stress signals predicts tumors in women with common pre-breast cancer

A specific biological response to cellular stress may predict the likelihood of future tumor formation of the most common, non-invasive form of pre-malignant breast cancer-- ductal carcinoma in situ, or DCIS.

13 Nov 2007

Molecular markers predict risk for invasive breast cancer years before the tumor develops

A team of scientists from the University of California San Francisco has identified distinct molecular markers that predict whether or not a woman is likely to develop subsequent invasive cancer after initial diagnosis with a noninvasive form of early breast cancer.

13 Nov 2007

MRI could help prevent breast cancer progression

Using magnetic resonance imaging (MRI) to diagnose breast cancer in its intraductal stage could help prevent the development of invasive cancer, conclude authors of an Article in The Lancet.

13 Aug 2007

Almac Diagnostics announces major study analysing ductal carcinoma in situ tissue samples

Today Almac Diagnostics announced a major study analysing ductal carcinoma in situ tissue samples using its novel Breast Cancer DSA microarray.

9 Aug 2007

Computer-aided detection essential in preventing breast cancer

Computer-aided detection improves breast cancers in both screening and diagnostic patients according to a recent study done by a private practice radiologist in Santa Barbara, CA.

2 Aug 2006

Breast removal not the only treatment option for non-invasive breast cancer

Breast conserving surgery, long known to be successful at treating the more common invasive cancer, can also be effective for this pre-invasive condition, according to a new study from researchers at the University of Michigan Comprehensive Cancer Center.

8 May 2006

Breast conserving surgery is a good option for early breast cancer

For women diagnosed with a type of non-invasive breast cancer, removing the breast is not the only treatment option.

8 May 2006

Osteoporosis drug Raloxifene shown to be as effective as Tamoxifen in preventing invasive breast cancer

Initial results of the Study of Tamoxifen and Raloxifene, or STAR, show that the drug raloxifene, currently used to prevent and treat osteoporosis in postmenopausal women, works as well as tamoxifen in reducing breast cancer risk for postmenopausal women at increased risk of the disease.

18 Apr 2006

Researchers release results of (STAR) breast cancer prevention trial

Below are comments from Len Lichtenfeld, MD, American Cancer Society deputy chief medical officer, in response to the results of the STAR trial.

18 Apr 2006

New risks identified after early breast cancer

A new study of women with early stage, localized breast cancer identifies new patterns and risk factors for invasive disease that may influence how patients are treated.

13 Apr 2006

Risk of invasive breast carcinoma among women diagnosed with ductal carcinoma in situ and lobular carcinoma in situ

A new study of women with early stage, localized breast cancer identifies new patterns and risk factors for invasive disease that may influence how patients are treated.

10 Apr 2006

Inflammation cuts both ways

Inflammation cuts both ways. When invaded by an infectious agent, for example, the body calls on the forces of inflammation to fight and defeat the intruder.

6 Apr 2006

Papillary lesions of the breast should be surgically excised to avoid missing a cancer

Certain breast lesions diagnosed as benign on core needle biopsy have cancer at surgical excision and thus should be removed, according to a study appearing in the March issue of Radiology.

28 Feb 2006

MRI can detect breast disease missed by mammography

Researchers have found that mammography coupled with magnetic resonance imaging (MRI) is extremely sensitive in the detection of ductal carcinoma in situ (DCIS). DCIS, or early stage breast carcinoma, is a pre-invasive malignancy and MRI may help identify this type of disease, which may not be visible on a mammogram.

16 Feb 2006

Breast ducts - A new site for cancer treatment!

Johns Hopkins Kimmel Cancer Center researchers are studying whether delivering chemotherapy drugs directly to breast "plumbing" might make treatment of early breast cancer easier on the patient and at least as good as surgery or radiation.

26 Jan 2006

Gene that regulates normal embryonic development is found at high levels in virtually all forms of breast cancer

A gene that appears to help regulate normal embryonic development is found at high levels in virtually all forms of breast cancer, according to a new study led by Laszlo Radvanyi, Ph.D., associate professor of breast and melanoma medical oncology at The University of Texas M. D. Anderson Cancer Center.

25 Jul 2005

New search method could aid in the discovery of biomarkers for breast cancer

Using a super-efficient method they invented to search for a type of cancer-related change in all genes of a cell, Dana-Farber Cancer Institute researchers have discovered new evidence about how the "microenvironment" of breast cancers helps drive the cancers' growth and migration.

13 Jul 2005

Density of breast tissue can directly influence tumour development

New research suggests that there is a direct relationship between the density of breast tissue, and the risk of developing tumours in dense areas of the breast.

8 Jun 2005