Dynamic Light Scattering News and Research

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Stability Testing of Therapeutic Proteins using DLS and Machine Learning

PIPPI scientists from different fields are developing methodologies, tools, and databases to guide the rational formulation of robust protein-based therapeutics. Their overall goal is to develop a database to guide product formulation development.

From Waters | Wyatt Technology 26 Jun 2019

Uncovering the Structure of HIV Integrase to Inform Drug Discovery

In this interview Dr Kushol Gupta, Research Assistant Professor in the Department of Biochemistry and Biophysics at the Perelman School of Medicine, University of Pennsylvania talks to News-Medical and Life Sciences about the importance of light scattering techniques for investigating structure and mechanism of action in his ongoing research into HIV integrase and the development of HIV therapeutics.

From Waters | Wyatt Technology 24 Apr 2019

Probing Submicron Protein Aggregation using Asymmetrical Flow Field-Flow Fractionation, AF4, and Light Scattering

The most recent developments by Wyatt in their instrumentation and software have made the full potential of FFF accessible to a wider user base. In this interview, Kim R. Williams and Christoph Johann talk to News-Medical and Life Sciences about the technologies and their research.

From Waters | Wyatt Technology 27 Mar 2019

Postnova Analytics AF4 system improves characterization of nanoformulated medicines

Postnova Analytics reports on a recent independent review which details how Asymmetric Flow Field Flow Fractionation is a valuable technique to improve the quality of nanoformulated medicines.

From Postnova Analytics 25 Feb 2019

Measuring nanocrystal length and thickness in just 40 minutes analysis time

Postnova Analytics reports on how Asymmetrical Flow Field Flow Fractionation coupled to Multi Angle Light Scattering (AF4-MALS) has been successfully used to characterize a polydisperse cellulose nanocrystal for size and thickness in just 40 minutes analysis time.

From Postnova Analytics 11 Sep 2018

Exosomes: Are They All Alike and Why Does it Matter?

In this interview, Haiying Zhang, Assistant Professor of Cell and Development Biology from the Department of Pediatrics at Weill Cornell Medicine talks to News – Medical about the importance of Exosomes.

From Waters | Wyatt Technology 1 Aug 2018

High Throughput Biophysical Screening for Development and Formulation of Biologics

In this interview, John Champagne, Ph.D. Senior Applications Scientist and Northeast Regional Manager for Wyatt Technology, talks to News-Medical about

From Waters | Wyatt Technology 1 Aug 2018

Engineer patents cost-effective method to remove endotoxins from fluids

By some estimates, 18 million people die each year from sepsis triggered by endotoxins – fragments of the outer membranes of bacteria.

13 Jul 2018

Comparing analytical techniques to detect and quantify silver nanoparticles

Postnova Analytics report on how researchers from the Institute for Health and Consumer Protection at the European Commission Joint Research Centre and the University of Ferrara have used AF2000 Asymmetric Flow Field Flow Fractionation system and Model S101 Sedimentation Flow Field Fractionation systems in some ground-breaking research.

From Postnova Analytics 27 Jun 2018

miniDAWN TREOS II SEC-MALS Detector for Essential Protein and Polymer Characterization

Wyatt Technology, the world leader in instrumentation for absolute macromolecular and nanoparticle characterization, announces the launch of its next generation multi-angle light scattering (MALS) detector for SEC/GPC, the miniDAWN® TREOS® II. The TREOS II is the only SEC-MALS detector for size exclusion or gel permeation chromatography that offers full field serviceability, extended ease-of-use, and a built-in upgrade path from HPLC to UHPLC technology.

From Waters | Wyatt Technology 3 May 2017

Particle Works offers wide range of nano- and microparticle materials with exceptional precision

Particle Works – a Blacktrace Holdings brand – is a world leader in the synthesis of nano- and microparticles. Combining state-of-the-art facilities with precision manufacturing expertise, the company can offer a wide range of bespoke services, including high throughput material discovery, process optimization and synthesis scale-up.

10 Feb 2017

Postnova Analytics announces 1-day seminar on advanced separation techniques

Postnova Analytics has announced a 1-day seminar examining the latest advanced separation techniques for the characterisation of nanoparticles, polymers and proteins.

19 Oct 2016

Could nanotechnology turn the cancer cell suicide switch back on? An interview with Professor Dipanjan Pan

Before I explain the discovery, I would take a step back and explain an interesting event that takes place in the cancer cells. Normal cells follow a rapid and irreversible process to efficiently eradicate dysfunctional cells. This is a natural process by which damaged cells commit ‘suicide’. This process is known as apoptosis or programmed cell death.

15 Aug 2016

Unique Postnova CF2000 system allows separation of complex particulate samples

The CF2000 Centrifugal Field Flow Fractionation (CF3) system from Postnova Analytics sets a new standard for high resolution separation and fractionation of nanoparticles.

From Postnova Analytics 19 May 2016

Extracellular Vesicle Isolation and Characterization

In this interview, News Medical talks to Dr. Carly Ross, from Beckman Coulter Life sciences about extracellular vesicle isolation and characterization.

From Beckman Coulter Life Sciences - Flow Cytometry 23 Mar 2016

Advances in the field of MPI: an interview with Professor Kannan Krishnan

In around 2004, there was a Phillips paper that discussed a new imaging technique called MPI. At that time, I had an eager, promising graduate student named Matt Ferguson who wanted a project, so I asked him to take a look.

From Bruker BioSpin - NMR, EPR and Imaging 1 Mar 2016

Dynamic light scattering technique may help detect people at risk of cataracts and presbyopia

As we age, proteins in the lenses of our eyes start misbehaving: They unfold and congregate in clusters that block, scatter and distort light as it passes through the lens. A cloudy area, or cataract, forms. In a new study, scientists found that throughout our lifetime, levels of a key protein decline, and may be an early warning sign of a developing cataract.

23 Dec 2015

Liposomal sizing and the Coulter principle: an interview with Professor Melvin E. Klegerman

For about the last 25 years, the cardiology group here have been developing a platform technology for both the diagnosis and treatment of atherosclerosis.

From Beckman Coulter Life Sciences - Particle Counting and Characterization 28 Oct 2015

Simple test outperforms current standard test for early-stage prostate cancer

A test that costs less than a $1 and yields results in minutes has been shown in newly published studies to be more sensitive and more exact than the current standard test for early-stage prostate cancer.

6 Apr 2015

Wyatt Technology highlights protein-protein interactions study investigated by dynamic light scattering

Wyatt Technology Corporation, the world leader in absolute macromolecular characterization instrumentation, is pleased to highlight a study recently authored by Martin Skov Neergaard from the Faculty of Health and Medical Sciences at the University of Copenhagen, “Protein-Protein Interactions Investigated by DLS: Determination at High and Low Protein Concentration.”

From Waters | Wyatt Technology 1 Jul 2014