Dysplasia News and Research

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Dysplasia is a term used in pathology to refer to an abnormality in maturation of cells within a tissue. This generally consists of an expansion of immature cells, with a corresponding decrease in the number and location of mature cells.

Combination of medications and light therapy effective against head and neck cancers

A combination of medications and a particular light therapy is effective at treating certain types of head and neck cancers in subtropical climates.

5 Oct 2009

Merck, QIAGEN to collaborate to increase access to HPV vaccination and HPV DNA testing in developing countries

Merck & Co., Inc. and QIAGEN N.V. today announced their intent to collaborate on a new program to increase access to HPV vaccination and HPV DNA testing in some of the most resource-poor areas of the world.

From QIAGEN Manchester Limited 24 Sep 2009

Center for Hip Pain and Preservation focuses on improved understanding of hip abnormalities

Recent improved understanding of hip abnormalities, combined with advances in diagnostic imaging techniques and minimally invasive surgical treatments are giving many patients new hope for relieving chronic, misdiagnosed hip pain.

21 Sep 2009

Multi-detector row computed tomography predicts malignancy of IPMNs

A clinical research article to be published on August 28, 2009 in the World Journal of Gastroenterology addresses the role of multi-detector row computed tomography (MDCT) in predicting malignancy of IPMNs preoperatively. The research team led by Prof. Wang DB from Ruijin Hospital of Shanghai Jiao Tong University School of Medicine recruited a total of 20 patients with pathologically-confirmed IPMNs in their study. Axial MDCT images combined with CT angiography (CTA) and multiplanar volume or curved reformations (MPVR or CR) were preoperatively acquired.

17 Sep 2009

Merck's GARDASIL receives approval from FDA Advisory Committee

Merck & Co., Inc. announced today that the U.S. Food and Drug Administration’s (FDA) Vaccines and Related Biological Products Advisory Committee agreed that efficacy, immunogenicity and safety data from clinical trials in males support the use of GARDASIL® [Human Papillomavirus Quadrivalent (Types 6, 11, 16 and 18) Vaccine, Recombinant] in boys and men 9 through 26 years of age for the prevention of genital warts caused by human papillomavirus (HPV) types 6 and 11.

10 Sep 2009

New method for neonatal icus reduces infection and lung distress in preemies

A new method for improving quality of care can reduce hospital-acquired infections and chronic respiratory distress with oxygen dependency in premature infants in neonatal ICUs, according to a new study in CMAJ (Canadian Medical Association Journal).

11 Aug 2009

Discovery of key gene for bone development that when mutated lead to dwarfism

Scientists have just discovered the gene behind Recessive Omodysplasia, a rare skeletal disease characterised by short-limbed dwarfism and craniofacial anomalies.

9 Jul 2009

New piece found in colorectal cancer puzzle

Prostasin, a relatively unknown protease enzyme expressed in most epithelial cells, may play a role in the genesis of colorectal cancer. Researchers writing in the open access journal BMC Cancer have associated a reduction in the expression of inhibitors of the enzyme with malignant cellular behavior.

24 Jun 2009

Potential new way to treat childhood epilepsy

Rutgers researchers have discovered a potential new way to treat childhood epilepsy using a widely available therapeutic drug.

10 Jun 2009

Radiofrequency ablation reverses Barrett's esophagus

Patients who have gastroesophageal reflux disease (GERD) for a prolonged period have an increased risk of developing Barrett's esophagus, a pre-cancerous condition where the tissue lining the esophagus becomes damaged by stomach acid and transformed into something like the inside of the stomach. New research finds that radiofrequency ablation -- an endoscopic procedure involving targeted thermal energy -- was very successful at restoring the esophagus and reducing risk for cancer.

2 Jun 2009

Radiofrequency ablation eradicates problems in most patients with Barrett's esophagus

A procedure that uses heat generated by radio waves to treat Barrett's esophagus, a condition caused by acid reflux (severe heartburn), can eliminate signs of the potentially cancer-causing disorder and reduce the risk that the disease will progress.

27 May 2009

TV series brings dwarfism into the spotlight

A popular cable reality television show, Little People, Big World, focuses on the daily lives of short stature individuals.

1 Apr 2009

Paradigm shift in the regulation of immune response

Over the past decade various pieces of the puzzle how signal transmission controls immunity have been coming together.

20 Mar 2009

Cause of severe pediatric epilepsy disorder discovered

Researchers at the University of California, San Diego School of Medicine have discovered that convulsive seizures in a form of severe epilepsy are generated, not on the brain's surface as expected, but from within the memory-forming hippocampus.

16 Mar 2009

Helix BioPharma receives approval to start phase II study of topical interferon alpha-2b in low-grade cervical lesions

Helix BioPharma Corp. announced that it has received the necessary regulatory approvals in Germany to initiate its planned Phase II pharmacokinetic study of Topical Interferon Alpha-2b in patients with low-grade cervical lesions.

16 Mar 2009

Better health and prosperity in Europe via improved clinical research

Improved patient-oriented research in Europe will benefit European citizens and the European medical industry and facilitate the transfer of scientific discoveries from the laboratory bench to the bedside. For Europe and for the rest of the world this effort will be of great importance for the quality of life of individuals and the wellbeing of society as a whole.

12 Mar 2009

Estrogen activates critical lung genes to improve lung function following preterm birth

Estrogen may be a new postnatal therapy to improve lung function and other outcomes in preterm infants, researchers at UT Southwestern Medical Center have found in an animal study.

12 Mar 2009

Estrogen may be a new postnatal therapy to improve lung function and other outcomes in preterm infants

"Ironically, a hormone that has received great attention as a potential means to optimize the health of older women may be a beneficial treatment for humans during the earliest stages of life," said Dr. Philip Shaul, professor of pediatrics at UT Southwestern and the study's senior author.

12 Mar 2009

Difluoromethylornithine may affect Barrett's esophagus

"While there was a suggestion that difluoromethylornithine (DFMO) may influence the extent of Barrett's dysplasia, this finding is very preliminary and further study of this agent in a larger number of patients is needed," said Frank A. Sinicrope, M.D., professor of medicine and oncology at the Mayo Clinic, Rochester, MN.

16 Nov 2008

Adalimumab therapy may reduce health-care costs for Crohn's disease patients

Inflammatory bowel disease (IBD) is a term that refers to both ulcerative colitis (UC) and Crohn's disease (CD).

12 Nov 2008

Dysplasia News and Research

Combination of medications and light therapy effective against head and neck cancers

Merck, QIAGEN to collaborate to increase access to HPV vaccination and HPV DNA testing in developing countries

Center for Hip Pain and Preservation focuses on improved understanding of hip abnormalities

Multi-detector row computed tomography predicts malignancy of IPMNs

Merck's GARDASIL receives approval from FDA Advisory Committee

New method for neonatal icus reduces infection and lung distress in preemies

Discovery of key gene for bone development that when mutated lead to dwarfism

New piece found in colorectal cancer puzzle

Potential new way to treat childhood epilepsy

Radiofrequency ablation reverses Barrett's esophagus

Radiofrequency ablation eradicates problems in most patients with Barrett's esophagus

TV series brings dwarfism into the spotlight

Paradigm shift in the regulation of immune response

Cause of severe pediatric epilepsy disorder discovered

Helix BioPharma receives approval to start phase II study of topical interferon alpha-2b in low-grade cervical lesions

Better health and prosperity in Europe via improved clinical research

Estrogen activates critical lung genes to improve lung function following preterm birth

Estrogen may be a new postnatal therapy to improve lung function and other outcomes in preterm infants

Difluoromethylornithine may affect Barrett's esophagus

Adalimumab therapy may reduce health-care costs for Crohn's disease patients

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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