Dysplasia News and Research

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Dysplasia is a term used in pathology to refer to an abnormality in maturation of cells within a tissue. This generally consists of an expansion of immature cells, with a corresponding decrease in the number and location of mature cells.

International studies show high efficacy for Gardasil

A new vaccine aimed at preventing cervical cancer is nearly 100 percent effective against the two types of the human papillomavirus (HPV) responsible for most cases of cervical cancer, strains 16 and 18.

1 Jun 2007

Advances in epilepsy treatment

Epilepsy and seizures affect 2.5 million Americans, 181,000 new cases of epilepsy are diagnosed every year, and the disorder incurs an estimated $12.5 billion in annual direct and indirect costs.

1 Jun 2007

Concentrated radio waves proide new approach to treating precancerous esophagus condition

The use of concentrated radio waves appears to be a safe and effective way to "burn" away abnormal cell growth in the esophagus that can be a precursor of cancer.

24 May 2007

Eating well still one of the best ways to prevent cancer and promote good health

We all know that eating fruits, vegetables and soy products provides essential nutrition for a healthy lifestyle, while obesity leads to the opposite.

16 Apr 2007

TGF-beta found to be a major player in causing bronchopulmonary dysplasia

Researchers from Massachusetts General Hospital, in collaboration with scientists from the Genzyme Corporation, have identified a potential treatment for a chronic lung disease affecting premature infants.

4 Apr 2007

Sheep gene research sheds light on human condition - ectodermal dysplasia

Sheep gene research at the University of Adelaide's Roseworthy Campus aimed at helping maximise wool production for Australian producers, has shed light on a human genetic hair and skin disorder.

4 Apr 2007

Optical biopsy finds cancers in first tests on human tissue

In its first laboratory tests on human tissue, a light-based probe built by researchers at Duke University's Pratt School of Engineering almost instantly detected the earliest signs of cancer in cells that line internal organs.

2 Apr 2007

Takeda acquires rights for drug to treat cervical dysplasia, HPV

Japanese pharmaceutical company Takeda on Friday announced that it has acquired from 3M the rights for a drug, called R-851, to treat cervical dysplasia and "high-risk" human papillomavirus infection, Reuters reports.

2 Apr 2007

Preemie lung treatments turn out to be safe

Preemies between 28 and 32 weeks are not harmed by a treatment no longer used to help their lungs mature before birth, according to findings of a study in this month's Pediatrics.

5 Mar 2007

Aspirin offers help for Barrett's esophagus

Researchers at Fred Hutchinson Cancer Research Center have found that people with the most-aggressive form of Barrett's esophagus, a precancerous condition that can lead to esophageal cancer, may benefit the most from preventive therapy with aspirin, ibuprofen and other nonsteroidal anti-inflammatory drugs, or NSAIDs.

27 Feb 2007

Investigational treatment for cervical dysplasia

Temple University Hospital's Center For Women's Health is participating in a national study to determine the safety and effectiveness of an investigational treatment for cervical dysplasia.

30 Jan 2007

Closing in on lethal arrhythmogenic right ventricular dysplasia in young athletes

Johns Hopkins experts on the genetics of a potentially lethal heart rhythm defect that runs in families and targets young athletes report they have greatly narrowed the hunt for the specific genetic mutations that contribute to the problem.

7 Sep 2006

Permanent renal parenchymal defects after febrile UTI are closely associated with vesicoureteric reflux

This study from Italy investigated the association of vesicoureteral reflux (VUR) and renal scarring.

5 Sep 2006

Renal transplantation in children with posterior uUrethral valves

The first description of posterior urethral valves (PUV) was made more than 80 years ago by Hugh Hampton Young and represents a spectrum of severity, ranging from disease incompatible with postnatal life to minimal symptoms that may not manifest until later in life.

17 Aug 2006

Nitric oxide reduces lung disease in premature, very-low-birth-weight infants

Delivering nitric oxide to the lungs of premature, very-low-birth-weight infants during their second week of life improves their chances of surviving without chronic lung disease, according to a national study of nearly 600 babies.

26 Jul 2006

Loss of Matrilin-3 gene leads to osteoarthritis

A gene that is associated with osteoarthritis and skeletal deformities in people has been shown to be responsible for preventing the onset of osteoarthritis in adult mice, according to a recent study led by Rhode Island Hospital.

24 Jul 2006

Researchers identify new disorder called cortical dysplasia-focal epilepsy syndrome

Researchers from the Translational Genomics Research Institute (TGen) and the Clinic for Special Children (CSC) in Strasburg, PA, have described a new childhood-onset disorder characterized by severe epilepsy and autistic traits, and identified its genetic basis.

11 Apr 2006

Photodynamic therapy may become the first line of treatment for Barrett's esophagus

When you think of heartburn, you probably think of greasy food, not cancer. You may not know that chronic heartburn is linked to esophageal cancer.

7 Apr 2006

Primary vesicoureteral reflux detected in neonates with a history of fetal renal pelvis dilatation

Fetal renal pelvis dilatation is a common abnormality, observed in 4.5% of pregnancies but surrounded by controversy regarding its significance. Working up renal pelvis dilation has become a standard of care regardless of the presence or absence of symptoms with vesicoureteral reflux (VUR) being one of the primary concerns.

8 Mar 2006

C-reactive protein helps identify progressive precancerous lesions in the lung

C-reactive protein (CRP), a biomarker for inflammation in the blood, can help to identify individuals whose abnormal precancerous lesions will advance closer to invasive lung cancer.

1 Mar 2006