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Could infants' robust immune responses reshape future vaccination strategies?

Utilizing next-gen sequencing techniques, researchers analyzed infants' immune responses to infections, uncovering a predominant innate immune activation unlike adults and older children. This insight could steer child vaccination research and pediatric infection management strategies, potentially revolutionizing infant healthcare.

3 Oct 2023

Zoonotic spillover safeguarding: computationally designed antigen targets range of coronaviruses

Researchers used an interdisciplinary approach incorporating phylogenetics, 3D protein modeling, and plasmid design to identify and computationally design an antigen representing the core of most currently known sarbecoviruses.

27 Sep 2023

Monkeypox mimics smallpox vaccine's immune response, new study reveals

The study in Nature Communications reveals that MPOX infection triggers an anti-viral antibody response akin to that from smallpox vaccination. Utilizing a comprehensive array of ELISAs, scientists found a high level of specificity and sensitivity in detecting antibodies against both MPOX and smallpox, offering a new, accurate way to measure immune responses.

26 Sep 2023

Intranasal vaccine shows promise against COVID variants in hamsters

Intranasal mRNA-LNP vaccines show promise in Syrian golden hamsters, effectively reducing SARS-CoV-2 viral loads and lung pathology. The study suggests potential efficacy against new variants, setting the stage for future research in human applications.

25 Sep 2023

Is sucralose the safer sweetener for your gut health?

The study found that consuming a beverage sweetened with sucrose significantly increased bacterial endotoxin levels in the blood, a marker for inflammation and gut barrier dysfunction, while no such effect was observed with sucralose-sweetened drinks. The findings suggest that sucralose may be a safer alternative to sucrose in terms of intestinal health and inflammation.

19 Sep 2023

Introducing Meteor™ chips on the IsoSpark™ platform: Advancing handsfree quantitative proteomics

We are pleased to introduce Meteor™ chips on the IsoSpark™ platform.

From Bruker Cellular Analysis 18 Sep 2023

Past infections may shape your COVID booster's punch against Omicron

This in-depth study examines how previous immunity impacts the effectiveness of COVID-19 booster vaccinations and susceptibility to Omicron breakthrough infections. The research highlights the significant role of individual immune histories in shaping both humoral and cellular responses to SARS-CoV-2, urging for more tailored vaccine strategies.

14 Sep 2023

HNP-1 may be a promising therapeutic agent for hypertensive left ventricular hypertrophy

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Human neutrophil peptide-1 (HNP-1) is a commonly investigated therapeutic agent.

14 Sep 2023

COVID-19 doubles risk of early type 1 diabetes signs in high-risk children

New research in JAMA finds a temporal association between SARS-CoV-2 infections and the onset of islet autoimmunity, a precursor to type 1 diabetes, in genetically predisposed infants. The study underscores COVID-19 as a potential risk factor for the development of this form of diabetes in young children.

13 Sep 2023

New class of iron-targeting compounds found to hamper proliferation of cancer cells

Researchers at the University of Arizona Cancer Center discovered a new class of iron-targeting compounds that hamper the proliferation of cultured malignant cells in a laboratory setting.

12 Sep 2023

Psoriasis vs. atopic dermatitis: New study reveals surprising inflammatory differences in age-specific groups

The hematological parameters and serum biomarkers of inflammation and immunity in patients with atopic dermatitis and psoriasis.

12 Sep 2023

How did COVID-19 pandemic restrictions impact invasive meningococcal disease trends?

The impact of COVID-19 pandemic restrictions on the incidence and strain distribution of meningococcus.

11 Sep 2023

Wearable technology emerges as a potential game-changer in early detection of COVID-19 among athletes

In a groundbreaking study conducted by Florida State University, wearable technology has emerged as a potential game-changer in the early detection of COVID-19 among NCAA Division I female student-athletes.

8 Sep 2023

Early viral exposure in mice weakens vaccine response, raising questions for human studies

Researchers at Washington University have demonstrated that early life exposure to multiple viruses in house mice dampens the immune response to SARS-CoV-2 vaccinations later in life. The study raises concerns about the applicability of common mouse models in immunological research, suggesting that prior pathogen exposure could be a significant variable in predicting vaccine efficacy.

5 Sep 2023

Study reports highly pathogenic avian influenza A infection in pet dogs and cat on a rural poultry farm in Italy

Researchers presented serological evidence of highly pathogenic avian influenza (HPAI) H5N1 virus infection in a pet cat and five dogs on a rural poultry farm in Italy.

4 Sep 2023

Intensive fasting boosts red blood cells' immune powers against COVID-19, study finds

Researchers found that short-term intensive fasting enhances the immune function of red blood cells, including their ability to combat SARS-CoV-2, without affecting their oxygen-carrying capacity. The study reveals that this fasting regimen popular in Asia could offer a multifaceted benefit by amplifying the body's defenses without compromising essential functions.

4 Sep 2023

Boosters slow antibody waning but hit a ceiling: Long-term COVID study reveals limits of immunity

The study tracks the long-term kinetics of antibody responses to SARS-CoV-2 after vaccination and infections in New York healthcare workers from 2020 to 2023. It reveals that antibody waning is slower after booster shots, but there's an upper limit to antibody levels, which gradually lowers with repeated SARS-CoV-2 exposures and vaccinations.

31 Aug 2023

Study finds evidence of SARS-CoV-2 exposure in many patients with postviral syndrome

Researchers investigated immunologic and clinical findings indicative of SARS-CoV-2 exposure among individuals with postviral syndrome.

29 Aug 2023

Small molecule inhibitor of the NLRP3 inflammasome for treating autoinflammatory diseases

Researchers described the preclinical profile of JT002, a novel and orally bioavailable small molecule inhibitor of the NLRP3 inflammasome.

24 Aug 2023

New method to assess the status of immune responses to specific antigens in detail

A new method to assess the status of immune responses to specific antigens in detail by analysis using the B cell receptor (BCR) repertoire has been developed by a research group, consisting of Assistant Professor Yohei Funakoshi, Associate Professor Kimikazu Yakushijin, Professor Hironobu Minami (Kobe University Graduate School of Medicine), Associate Professor Goh Ohji (Kobe University Hospital), and Researcher Takaji Matsutani (Repertoire Genesis Inc.).

18 Aug 2023