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Spice herbs for diabetes treatment: A focus on Trachyspermum ammi and Pimpinella anisum

Announcing a new article publication for BIO Integration journal. Diabetes mellitus (DM) arises from a cascade of factors, primarily stemming from defective insulin secretion by the pancreas and emergence of insulin resistance.

25 Sep 2023

Researchers develop new method to deliver strong antibiotic drugs more safely

Antibiotic resistant bacteria are a threat to human lives, and yet the development of new drugs to treat bacterial infections is slow.

25 Sep 2023

Is the implementation of contact precautions crucial for preventing healthcare-associated MRSA?

The designation of contact precautions as an "essential practice" for MRSA prevention.

25 Sep 2023

Tirzepatide outshines other treatments in lowering blood sugar and weight for type 2 diabetes patients

Meta-analysis finds tirzepatide to be the most effective GLP-1 receptor agonist for glucose and weight control in type 2 diabetes patients. The study suggests tirzepatide could be preferable in initial stages of the disease, while other GLP-1 receptor agonists combined with insulin are equally effective for long-term diabetics.

25 Sep 2023

Could CaMKK2 enzyme be the key to treating bipolar disorder?

Researchers explore the role of the CaMKK2 signaling pathway in bipolar disorder, suggesting it as a new treatment target. By targeting this enzyme, scientists aim to develop more effective therapies for bipolar symptoms and metabolic dysfunction.

24 Sep 2023

Could metformin be a game changer for heart health in non-diabetics?

Using Mendelian randomization, researchers found that altering seven metformin targets led to improved blood pressure and BMI in non-diabetic individuals. The study suggests the potential for metformin's role in reducing cardiovascular risks in the general population, although more research is needed.

24 Sep 2023

Plant-based proteins boost muscle mass and cut fat in older adults

Plant-based proteins are just as effective as animal-based options in maintaining muscle mass and strength in older adults, a new meta-analysis finds. The study shows that plant proteins can even aid in reducing fat mass, offering a sustainable and healthful option for combating age-related muscle decline.

24 Sep 2023

Tirzepatide superior to semaglutide for blood sugar control and body weight loss

A new meta-analysis combining 22 studies, to be presented at this year's Annual Meeting of the European Association for the Study of Diabetes (EASD) in Hamburg, Germany (2-6 October), shows that tirzepatide is superior to semaglutide for both control of blood sugar and in terms of amount of body weight lost by patients.

22 Sep 2023

Peptide vaccine targets H3K27M mutation in midline gliomas, shows promise in early trials

Tumor vaccines can help the body fight cancer. These vaccines alert the patient's immune system to proteins that are carrying cancer-typical alterations.

22 Sep 2023

VAX-seq: the future of mRNA vaccine analysis and quality assurance?

Researchers proposed a simplified approach for analyzing mRNA vaccines using long-read sequencing.

22 Sep 2023

Inhaled fluticasone furoate falls flat in speeding up COVID-19 recovery, says ACTIV-6 trial

The ACTIV-6 trial investigated the effectiveness of inhaled fluticasone furoate on mild-to-moderate COVID-19 cases and found it did not accelerate recovery or prevent clinical progression compared to a placebo. Interestingly, vaccinated participants showed slightly faster recovery when treated with the drug, while unvaccinated participants did not.

21 Sep 2023

Pitt launches trial to test interventions for life-threatening bleeding in injured children

The No. 1 cause of death in children is trauma. There are an estimated 2,000 pediatric deaths from traumatic bleeding in the U.S. each year that are preventable with optimal care, yet there have been no large-scale clinical trials to guide the best way to resuscitate children with life-threatening bleeding from traumatic injury.

21 Sep 2023

Unlocking the power of mRNA vaccines: From COVID-19 to cancer and beyond

A comprehensive review in Signal Transduction and Targeted Therapy delves into the versatility and effectiveness of mRNA vaccines, from their game-changing role in COVID-19 to potential applications in cancer and rare diseases. Despite drawbacks like stability and high immunogenicity, advancements in vaccine technology have poised mRNA platforms as a robust tool for both preventive and therapeutic interventions.

21 Sep 2023

ACT and personalized cancer vaccine combo shows efficacy in ovarian cancer patients

A Ludwig Cancer Research study has shown that combining adoptive T cell therapy (ACT) with an innovative, personalized cancer vaccine under development at the Lausanne Branch of the Ludwig Institute for Cancer Research can benefit patients with late-stage, drug-resistant ovarian cancer.

21 Sep 2023

Efficacy News and Research

Spice herbs for diabetes treatment: A focus on Trachyspermum ammi and Pimpinella anisum

Researchers develop new method to deliver strong antibiotic drugs more safely

Is the implementation of contact precautions crucial for preventing healthcare-associated MRSA?

Tirzepatide outshines other treatments in lowering blood sugar and weight for type 2 diabetes patients

Could CaMKK2 enzyme be the key to treating bipolar disorder?

Could metformin be a game changer for heart health in non-diabetics?

Plant-based proteins boost muscle mass and cut fat in older adults

Tirzepatide superior to semaglutide for blood sugar control and body weight loss

Peptide vaccine targets H3K27M mutation in midline gliomas, shows promise in early trials

VAX-seq: the future of mRNA vaccine analysis and quality assurance?

Inhaled fluticasone furoate falls flat in speeding up COVID-19 recovery, says ACTIV-6 trial

Pitt launches trial to test interventions for life-threatening bleeding in injured children

Unlocking the power of mRNA vaccines: From COVID-19 to cancer and beyond

ACT and personalized cancer vaccine combo shows efficacy in ovarian cancer patients

Manipulating mitochondrial electron flow enhances immune response, reduces tumor growth

Brazilian fruits positively impact gut health and chronic disease prevention

USC develops innovative system for conducting preclinical research on potential stroke treatments

Creating CAR-T cells with enhanced immune memory to fight cancer

Doctors need better guidance on treating ADHD in over 50s

Study explores the efficacy of smoking interventions in new and expectant fathers

Arrayed CRISPR Screening for Revolutionizing Target Discovery

Innovations in baculovirus–insect cell expression systems

Compound Management and its Crucial Role in Early Pharmaceutical Research

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